Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nadia Leloup"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Type-I transmembrane proteins represent a large group of 1,412 proteins in humans with a multitude of functions in cells and tissues. They are characterized by an extracellular, or luminal, N-terminus followed by a single transmembrane helix and a cy
Externí odkaz:
https://doaj.org/article/3939649fae2e4a37bdc8f156f7725dbe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The Sortilin-related CNS-expressed receptor 2 (SorCS2)–proneurotrophin signaling system regulates neuronal plasticity and its dysfunction is linked to schizophrenia. Here the authors present the structures of the SorCS2 ectodomain alone and in comp
Externí odkaz:
https://doaj.org/article/a272131e31ee4e99a1f0ca5d3e9dd5cb
Autor:
Nadia Leloup, Philip Lössl, Dimphna H. Meijer, Martha Brennich, Albert J. R. Heck, Dominique M. E. Thies-Weesie, Bert J. C. Janssen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Sortilin is an endocytosis receptor with a luminal β-propeller domain. Here the authors present the structures of the β-propeller domain at neutral and acidic pH, which reveal that sortilin dimerises and undergoes conformational changes at low pH a
Externí odkaz:
https://doaj.org/article/6012de2c7ca2445a89156e52dab21cee
Autor:
Alexis D. Corrado, Akiko Koide, Wei Zhang, Nadia Leloup, Gayatri Ketavarapu, Takamitsu Hattori, Julien Oury, Steven J. Burden, Shohei Koide
Publikováno v:
Nature. 595:404-408
Congenital myasthenia (CM) is a devastating neuromuscular disease, and mutations in DOK7, an adaptor protein that is crucial for forming and maintaining neuromuscular synapses, are a major cause of CM1,2. The most common disease-causing mutation (DOK
Autor:
Waldemar Vollmer, Eefjan Breukink, Alexander J. F. Egan, Bert J. C. Janssen, Nathaniel I. Martin, Inge L. van't Veer, Nadia Leloup
Publikováno v:
ChemBioChem. 17:2207-2207
Autor:
Davies, Christopher W., Vidal, Simon E., Phu, Lilian, Sudhamsu, Jawahar, Hinkle, Trent B., Chan Rosenberg, Scott, Schumacher, Frances-Rose, Zeng, Yi Jimmy, Schwerdtfeger, Carsten, Peterson, Andrew S., Lill, Jennie R., Rose, Christopher M., Shaw, Andrey S., Wertz, Ingrid E., Kirkpatrick, Donald S., Koerber, James T.
Publikováno v:
Nature Communications; 7/29/2021, Vol. 12 Issue 1, p1-19, 19p
Autor:
Zeronian, Matthieu R., Klykov, Oleg, i de Montserrat, Júlia Portell, Konijnenberg, Maria J., Gaur, Anamika, Scheltema, Richard A., Janssen, Bert J. C.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/27/2021, Vol. 118 Issue 30, p1-12, 12p
Autor:
Leloup, Nadia, Meijer, Dimphna H., Janssen, Bert J. C., Lössl, Philip, Heck, Albert J. R., Brennich, Martha, Thies-Weesie, Dominique M. E.
Publikováno v:
Nature Communications; 11/22/2017, Vol. 8 Issue 1, p1-16, 16p
Autor:
PR Newswire
Publikováno v:
PR Newswire US. 06/23/2021.
Autor:
Birkinshaw, Richard W., Gong, Jia-nan, Luo, Cindy S., Lio, Daisy, White, Christine A., Anderson, Mary Ann, Blombery, Piers, Lessene, Guillaume, Majewski, Ian J., Thijssen, Rachel, Roberts, Andrew W., Huang, David C. S., Colman, Peter M., Czabotar, Peter E.
Publikováno v:
Nature Communications; 6/3/2019, Vol. 10 Issue 1, pN.PAG-N.PAG, 1p