Cerebellar contributions across behavioural timescales: a review from the perspective of cerebro-cerebellar interactions

Autor: Ellen Boven, Nadia L. Cerminara

Publikováno v: Frontiers in Systems Neuroscience, Vol 17 (2023)

Performing successful adaptive behaviour relies on our ability to process a wide range of temporal intervals with certain precision. Studies on the role of the cerebellum in temporal information processing have adopted the dogma that the cerebellum i

Externí odkaz: https://doaj.org/article/b31a478082714549971644ac1d55917b

Cerebello-Thalamo-Cortical Network Dynamics in the Harmaline Rodent Model of Essential Tremor

Autor: Kathryn Woodward, Richard Apps, Marc Goodfellow, Nadia L. Cerminara

Publikováno v: Frontiers in Systems Neuroscience, Vol 16 (2022)

Essential Tremor (ET) is a common movement disorder, characterised by a posture or movement-related tremor of the upper limbs. Abnormalities within cerebellar circuits are thought to underlie the pathogenesis of ET, resulting in aberrant synchronous

Externí odkaz: https://doaj.org/article/431ea5b3587c423e8090427939f36679

Neuronal activity patterns in microcircuits of the cerebellar cortical C3 zone during reaching

Autor: Nadia L. Cerminara, Martin Garwicz, Henry Darch, Conor Houghton, Dilwyn E. Marple‐Horvat, Richard Apps

Publikováno v: Cerminara, N L, Garwicz, M, Darch, H, Houghton, C, Marple-Horvat, D E & Apps, R 2022, ' Neuronal activity patterns in microcircuits of the cerebellar cortical C3 zone during reaching ', Journal of Physiology, vol. 600, no. 23, pp. 5077-5099 . https://doi.org/10.1113/JP282928

KEY POINTS: A defining feature of cerebellar organization is its division into a series of zones and smaller subunits termed microzones. Much of how zones and microzones are organized has been determined in anaesthetized preparations, and little is k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94851b5bdd86e662ff3d81e1932e4fd
https://research-information.bris.ac.uk/en/publications/50882402-fb0c-41db-89df-e99f544c2ccb

Sensory and Motor Electrophysiological Mapping of the Cerebellum in Humans

Autor: Reiko Ashida, Nadia L Cerminara, Richard Apps, Jonathan C W Brooks, Richard J. Edwards, Peter Walsh

Publikováno v: Ashida, R, Walsh, P, Brooks, J C W, Cerminara, N L, Apps, R & Edwards, R J 2022, ' Sensory and motor electrophysiological mapping of the cerebellum in humans ', Scientific Reports, vol. 12, no. 1, 177, pp. 177 . https://doi.org/10.1038/s41598-021-04220-9
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Scientific Reports

Damage to the cerebellum during posterior fossa surgery can lead to ataxia and in paediatric cases, the risk of cerebellar mutism syndrome. Animal electrophysiological and human imaging studies have shown compartmentalisation of sensorimotor and cogn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc459f397da4bdf6bbff180fc1ef154
https://doi.org/10.21203/rs.3.rs-537226/v1

A Purkinje cell model that simulates complex spikes

Autor: Richard Apps, Amelia Burroughs, Conor J. Houghton, Nadia L Cerminara

Purkinje cells are the principal neurons of the cerebellar cortex. One of their distinguishing features is that they fire two distinct types of action potential, called simple and complex spikes, which interact with one another. Simple spikes are ste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09556fdb4818c5ab7127fb045d548728
https://doi.org/10.1101/2020.05.18.102236