A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data.

Autor: Shauna D O'Donovan, Michael Lenz, Roel G Vink, Nadia J T Roumans, Theo M C M de Kok, Edwin C M Mariman, Ralf L M Peeters, Natal A W van Riel, Marleen A van Baak, Ilja C W Arts

Publikováno v: PLoS Computational Biology, Vol 15, Iss 10, p e1007400 (2019)

Given the association of disturbances in non-esterified fatty acid (NEFA) metabolism with the development of Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease, computational models of glucose-insulin dynamics have been extended to account for the

Externí odkaz: https://doaj.org/article/410efcecc5b248518df708c5720dcd97

Biomimetic Mechanically Strong One-Dimensional Hydroxyapatite/Poly(d,l-lactide) Composite Inducing Formation of Anisotropic Collagen Matrix

Autor: Yonggang Zhang, Lorenzo Moroni, Jiaping Li, Nadia J. T. Roumans, Vivian Hilda Maria Mouser, Pamela Habibovic

Publikováno v: ACS Nano
ACS Nano, 15(11), 17480-17498. American Chemical Society

Natural bone is a complex composite, consisting predominantly of collagen and hydroxyapatite (HA), which form a highly organized, hierarchical structure from the nano- to the macroscale. Because of its biphasic, anisotropic, ultrafine structural desi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf9ecc5cb60ea22926742c4514d24c8
http://europepmc.org/articles/PMC8613905

Expanding Biomaterial Surface Topographical Design Space through Natural Surface Reproduction

Autor: Jan de Boer, Steven Vermeulen, Morgan R. Alexander, Paul Williams, Jorge Alfredo Uquillas, Floris Honig, Manuel Romero, Aurélie Carlier, Aysegul Dede Eren, Urnaa Tuvshindorj, Aliaksei S Vasilevich, Nadia J. T. Roumans

Publikováno v: Advanced Materials, 33(31):2102084. Wiley-VCH Verlag

Surface topography is a tool to endow biomaterials with bioactive properties. However, the large number of possible designs makes it challenging to find the optimal surface structure to induce a specific cell response. The TopoChip platform is curren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba163e5a2984ad480de687a59952f4f
https://research.tue.nl/nl/publications/824a2bdf-14c7-4788-bf32-db346b586735

Diet Composition, Glucose Homeostasis, and Weight Regain in the YoYo Study

Autor: Marleen A. van Baak, Edwin C. M. Mariman, Nadia J. T. Roumans

Publikováno v: Nutrients, Vol 13, Iss 2257, p 2257 (2021)
Nutrients, 13(7):2257. Multidisciplinary Digital Publishing Institute (MDPI)
Nutrients
Volume 13
Issue 7

Based on several randomized clinical trials, it has been suggested that baseline glucose homeostasis interacts with the influence of diet composition on weight loss and weight loss maintenance. In this secondary analysis of the YoYo study, a study in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797d317c0118f884df9f158e5f9ec79a
https://cris.maastrichtuniversity.nl/en/publications/8e2bc3f6-90d0-4a1d-990b-449bc8ca24ee

Identification of topographical architectures supporting the phenotype of rat tenocytes

Autor: Dimitrios Tsiapalis, Nadia J. T. Roumans, Aliaksei Vasilevich, Nick R.M. Beijer, Steven Vermeulen, Aysegul Dede Eren, Jan de Boer, Dimitrios I. Zeugolis, Pascal Vroemen

Publikováno v: Acta Biomaterialia, 83, 277-290. Elsevier / Bunge
Acta Biomaterialia, 83, 277-290. Elsevier
Acta Biomaterialia

Tenocytes, the main cell type of the tendon, require mechanical stimuli for their proper function. When the tenocyte environment changes due to tissue damage or by transferring tenocytes from their native environment into cell culture, the signals fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380bab1155fe01dae67bba093b3b8a3a
https://doi.org/10.1016/j.actbio.2018.10.041