Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nadia Garman"'
Autor:
Heide Stirnadel-Farrant, Mahesh Kudari, Nadia Garman, Jessica Imrie, Bikramjit Chopra, Stefania Giannelli, Michela Gabaldo, Ambra Corti, Stefano Zancan, Alessandro Aiuti, Maria Pia Cicalese, Rohit Batta, Jonathan Appleby, Mario Davinelli, Pauline Ng
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-10 (2018)
Abstract Background Strimvelis (autologous CD34+ cells transduced to express adenosine deaminase [ADA]) is the first ex vivo stem cell gene therapy approved by the European Medicines Agency (EMA), indicated as a single treatment for patients with ADA
Externí odkaz:
https://doaj.org/article/a8893f1115da49d982593a6f5bd7315f
Autor:
Toby M. Maher, Arthur R. Kang’ombe, Allan Listanco, Azeem Saleem, Richard P. Marshall, Joaquim Ramada-Magalhaes, Gisli Jenkins, Maria Costa, Christopher Coello, Pauline T. Lukey, James Davies, Sara Moz, Stuart Kendrick, Roger N. Gunn, Nadia Garman, Christine A. Parker, William A. Fahy, Mayca Onega, Jan Passchier, Frederick J. Wilson
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
PurposeThe RGD-integrin, αvβ6, plays a role in the pathogenesis of pulmonary fibrosis through activation of transforming growth factor beta (TGFβ). This study sought to quantify expression of αvβ6 in the lungs of healthy humans and subjects with
Autor:
R. Thomas Lumbers, Pauline T. Lukey, Jan Passchier, Nadia Garman, Nicholas Keat, Robert J. Slack, Mayca Onega, Azeem Saleem, Keguan Chen, Julia Kenny, William A. Hallett, Christine A. Parker
Publikováno v:
Journal of Nuclear Medicine Technology. 46:136-143
The αvβ6 integrin is involved in the pathogenesis of cancer and fibrosis. A radiolabeled 20-amino-acid αvβ6-binding peptide, derived from the foot and mouth virus (NAVPNLRGDLQVLAQKVART [A20FMDV2]), has been developed to image αvβ6 levels precli
Autor:
Richard P. Marshall, David Fairman, Simon Parry, Pauline T. Lukey, Stuart Kendrick, Juliet Kay Simpson, Nadia Garman, Maria J. Costa, William A. Fahy, Robert J. Slack, Charlotte H. Maden, Michelle Chalker, Tim Mant
Publikováno v:
European Journal of Clinical Pharmacology
Purpose Inhaled drug delivery is an attractive route by which to deliver drugs to lungs of patients with idiopathic pulmonary fibrosis (IPF). GSK3008348 is a potent and selective small molecule being developed as the first inhaled inhibitor of the α
Autor:
Nicholas, Keat, Julia, Kenny, Keguan, Chen, Mayca, Onega, Nadia, Garman, Robert J, Slack, Christine A, Parker, R Thomas, Lumbers, Will, Hallett, Azeem, Saleem, Jan, Passchier, Pauline T, Lukey
Publikováno v:
Journal of nuclear medicine technology. 46(2)
The α
Autor:
Diederick E. Grobbee, Rutger van den Bor, Veronica Walsh, Catherine Harvey, Elaine A. Irving, Rafael Alfonso-Cristancho, Nadia Garman, Paco M J Welsing
Publikováno v:
Journal of Clinical Epidemiology, 91, 6. Elsevier USA
Pragmatic trials offer the opportunity to obtain real-life data on the relative effectiveness and safety of a treatment before or after market authorisation. This is the penultimate paper in a series of eight, describing the impact of design choices