Characterization of hyperlipidemia secondary to mitotane in adrenocortical carcinoma

Autor: Nadia Gagnon, Sophie Bernard, Martine Paquette, Catherine Alguire, André Lacroix, Pierre-Olivier Hétu, Harold J Olney, Isabelle Bourdeau

Publikováno v: Endocrine Oncology, Vol 2, Iss 1, Pp 1-8 (2023)

Background: This study examined the magnitude of changes and the time required to observe maximal changes in LDL-c, HDL-c, triglycerides (Tg) and non-HDL-c after the introduction of mitotane. Methods: Retrospective study of 45 patients with adrenocor

Externí odkaz: https://doaj.org/article/75e3f356ce144307ac6c7eb046486f27

Small adrenal incidentaloma becoming an aggressive adrenocortical carcinoma in a patient carrying a germline APC variant

Autor: Harold J. Olney, Catherine Beauregard, Mathieu Latour, Isabelle Bourdeau, Fred Saad, Catherine Alguire, Zaki El Haffaf, Irina Bancos, Gilles Corbeil, Katia Caceres, Pascale Boily, Nadia Gagnon

Publikováno v: Endocrine. 68:203-209

Recent guidelines on adrenal incidentalomas suggested in patients with an indeterminate adrenal mass and no significant hormone excess that follow up with a repeat noncontrast CT or MRI after 6–12 months may be an option. We report the case of a 32

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8fcc7f7e7156994e73419dbf42f1529
https://doi.org/10.1007/s12020-020-02209-4

Recovery of adrenal insufficiency is frequent after adjuvant mitotane therapy in patients with adrenocortical carcinoma

Autor: Jonathan Poirier, Isabelle Bourdeau, Massimo Terzolo, Nada El Ghorayeb, André Lacroix, Nadia Gagnon, Anna Calabrese, Soraya Puglisi

Publikováno v: Cancers, Vol 12, Iss 3, p 639 (2020)
Cancers
Volume 12
Issue 3

Mitotane is a steroidogenesis inhibitor and adrenolytic drug used for treatment of adrenocortical cancer (ACC). Mitotane therapy causes adrenal insufficiency requiring glucocorticoid replacement in all patients. However, it is unclear whether chronic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe0aa42ee285fc16971e6e32319a1ce
http://hdl.handle.net/2318/1743741

Genetic Characterization of GnRH/LH-Responsive Primary Aldosteronism

Autor: Natasha Ludwig, Nada El Ghoyareb, Gilles Corbeil, Nadia Gagnon, Mathieu Latour, Katia Y Cáceres-Gorriti, Isabelle Bourdeau, André Lacroix

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 103:2926-2935

Background Recently, somatic β-catenin mutations (CTNNB1) identified in aldosterone-producing adenomas (APAs) from three women were suggested to be responsible for the aberrant overexpression of luteinizing hormone/choriogonadotropin receptor and go

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d838257184233ca59562abc57d103aa
https://doi.org/10.1210/jc.2018-00087

Response to Letter to the Editor: 'CT Characteristics of Pheochromocytoma: Relevance for the Evaluation of Adrenal Incidentaloma'

Autor: Vasileios Chortis, Corin Badiu, Anneke Visser, Wiebke Arlt, Massimo Mannelli, Urszula Ambroziak, Aakanksha Khanna, Irina Bancos, William F. Young, Michiel N. Kerstens, Letizia Canu, Laurent Vroonen, Marcin Motyka, Ewelina Rzepka, Marie Buchy, Henri J L M Timmers, Felix Beuschlein, Cristina Lamas, Darko Kastelan, Françoise Borson-Chazot, Ariadni Spyroglou, Benjamin G. Challis, Robert P. Hartman, Magalie Haissaguerre, Ruth T Casey, Isabelle Bourdeau, Antoine Tabarin, Edward Buitenwerf, Alicja Hubalewska-Dydejczyk, Nadia Gagnon, Martin Fassnacht, Timo Deutschbein, Marcus Quinkler, Ivana Kraljević, Janna A W Van Hemert

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 105
Journal of Clinical Endocrinology and Metabolism, 105(10):472. ENDOCRINE SOC
Journal of Clinical Endocrinology and Metabolism, 105, 10

Contains fulltext : 225780.pdf (Publisher’s version ) (Closed access)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87b9d0c69f6ff3c99070b3efac43b7d
https://doi.org/10.1210/clinem/dgaa472