Notch signaling is involved in human articular chondrocytes de-differentiation during osteoarthritis

Autor: Moncef Hamdoun, Nadia Gadgadi, Slaheddine Sellami, Behrouz Zandieh-Doulabi, Jenneke Klein Nulend, Mohamed Allouche, Nadia Sassi, Slim Mourali, Lilia Laadhar, Sondes Makni

Publikováno v: Sassi, N, Gadgadi, N, Laadhar, L, Allouche, M, Mourali, S, Zandieh-Doulabi, B, Hamdoun, M, Klein Nulend, J, Makni, S & Sellami, S 2014, ' Notch signaling is involved in human articular chondrocytes de-differentiation during osteoarthritis ', Journal of Receptors and Signal Transduction Research, vol. 34, no. 1, pp. 48-57 . https://doi.org/10.3109/10799893.2013.856920
Journal of Receptors and Signal Transduction Research, 34(1), 48-57. Informa Healthcare

Context: During osteoarthritis (OA), chondrocytes undergo de-differentiation, resulting in the acquisition of a fibroblast-like morphology, decreased expression of collagen type II (colII) and aggrecan, and increased expression of collagen type I (co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c906aa89f4cda343ab8e97c66ff1ca5d
https://doi.org/10.3109/10799893.2013.856920