Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nadia Dubé"'
Autor:
Zhen-Yuan Lin, Anne-Claude Gingras, Viviane Tran, Jonathan Boulais, Halil Bagci, Islam E. Elkholi, Amélie Robert, David R. Hipfner, Marie-Pier Thibault, Nadia Dubé, Neera Sriskandarajah, Jean-François Côté, Denis Faubert
Publikováno v:
Nature Cell Biology. 22:120-134
Guanine nucleotide exchange factors (RhoGEFs) and GTPase-activating proteins (RhoGAPs) coordinate the activation state of the Rho family of GTPases for binding to effectors. Here, we exploited proximity-dependent biotinylation to systematically defin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e380dbe8893cb96faabbd1bcfc920bdf
https://doi.org/10.1038/s41556-019-0438-7
https://doi.org/10.1038/s41556-019-0438-7
Autor:
Halil, Bagci, Neera, Sriskandarajah, Amélie, Robert, Jonathan, Boulais, Islam E, Elkholi, Viviane, Tran, Zhen-Yuan, Lin, Marie-Pier, Thibault, Nadia, Dubé, Denis, Faubert, David R, Hipfner, Anne-Claude, Gingras, Jean-François, Côté
Publikováno v:
Nature cell biology. 22(1)
Guanine nucleotide exchange factors (RhoGEFs) and GTPase-activating proteins (RhoGAPs) coordinate the activation state of the Rho family of GTPases for binding to effectors. Here, we exploited proximity-dependent biotinylation to systematically defin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa6a72c8699f005faae6de5c1562a71b
https://pubmed.ncbi.nlm.nih.gov/32042180
https://pubmed.ncbi.nlm.nih.gov/32042180
Autor:
Anne-Claude Gingras, Amélie Robert, Nadia Dubé, David R. Hipfner, Neera Sriskandarajah, Viviane Tran, Denis Faubert, Islam E. Elkholi, Zhen-Yuan Lin, Jean-François Côté, Marie-Pier Thibault, Jonathan Boulais, Halil Bagci
Publikováno v:
Nature Cell Biology. 22:353-353
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa9c838fb1846aac9a6d63e73cded74
https://doi.org/10.1038/s41556-020-0479-y
https://doi.org/10.1038/s41556-020-0479-y
Autor:
Daniel Sinnett, Emile Levy, Ernest G. Seidman, Alain Montoudis, Moise Bendayan, Edgard Delvin, Nadia Dubé, Jean-François Beaulieu, Geneviève Mailhot, Daniel Ménard
Publikováno v:
Histochemistry and Cell Biology. 132:351-367
Although intestinal (I) and liver (L) fatty acid binding proteins (FABP) have been widely studied, the physiological significance of the presence of the two FABP forms (I- and L-FABP) in absorptive cells remains unknown as do the differences related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0087df867fbcd9acf9d481515ed1e6
https://doi.org/10.1007/s00418-009-0608-y
https://doi.org/10.1007/s00418-009-0608-y
Autor:
Veena Sangwan, Michel L. Tremblay, Anie Monast, Morag Park, Nadia Dubé, Grigorios N. Paliouras, Jasmine V. Abella
Publikováno v:
Journal of Biological Chemistry. 283:34374-34383
The non-receptor protein-tyrosine phosphatases (PTPs) 1B and T-cell phosphatase (TCPTP) have been implicated as negative regulators of multiple signaling pathways including receptor-tyrosine kinases. We have identified PTP1B and TCPTP as negative reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c76aae9f1d0e7483e68d0402466e85
https://doi.org/10.1074/jbc.m805916200
https://doi.org/10.1074/jbc.m805916200
Autor:
Judith Klumperman, Nadia Dubé, Johannes L. Bos, Marjolein J. Vliem, Willem-Jan Pannekoek, Viola Oorschot, Holger Rehmann, Matthijs R.H. Kooistra
Publikováno v:
Cellular Signalling. 20:1608-1615
The small G-protein Rap1 is a critical regulator of cell–cell contacts and is activated by the remodeling of adherens junctions. Here we identify the Rap1 guanine nucleotide exchange factor PDZ-GEF2 as an upstream activator of Rap1 required for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2a94511fa6a9ed915d11a1b5b315e0
https://doi.org/10.1016/j.cellsig.2008.05.006
https://doi.org/10.1016/j.cellsig.2008.05.006
Autor:
Sofi G. Julien, Yongxin Han, Brian P. Kennedy, Marilène Paquet, Nadia Dubé, Michel L. Tremblay, Michelle Read, Janice Penney, William J. Muller
Publikováno v:
Nature Genetics. 39:338-346
We investigated the role of protein tyrosine phosphatase 1B (PTP1B) in mammary tumorigenesis using both genetic and pharmacological approaches. It has been previously shown that transgenic mice with a deletion mutation in the region of Erbb2 encoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c76fd39ede1b5129e3292931c77e36b
https://doi.org/10.1038/ng1963
https://doi.org/10.1038/ng1963
Autor:
Alan Cheng, Nadia Dubé, Veena Sangwan, Grigorios N. Paliouras, Michel L. Tremblay, Morag Park
Publikováno v:
Journal of Biological Chemistry. 281:221-228
Genetic disruption of protein-tyrosine phosphatase 1B (PTP1B) in mice leads to increased insulin sensitivity and resistance to weight gain. Although PTP1B has been implicated as a regulator of multiple signals, its function in other physiological res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1583d2179977bfcc58cf6a3d9f4fa38
https://doi.org/10.1074/jbc.m507858200
https://doi.org/10.1074/jbc.m507858200
Autor:
Nadia Dubé, Michel L. Tremblay
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1754:108-117
As in other fields of biomedical research, the use of gene-targeted mice by homologous recombination in embryonic stem cells has provided important findings on the function of several members of the protein tyrosine phosphatase (PTP) family. For inst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9c892ed0653369061dbebd7133f8a2
https://doi.org/10.1016/j.bbapap.2005.07.030
https://doi.org/10.1016/j.bbapap.2005.07.030
Autor:
Nadia Dubé, Alan Cheng, Annie Bourdeau, Ailsa Lee Loy, Krista M. Heinonen, Michel L. Tremblay
Publikováno v:
Cancer Research. 65:10088-10095
Protein tyrosine phosphatase 1B (PTP1B) is involved in multiple signaling pathways by down-regulating several tyrosine kinases. For example, gene-targeting studies in mice have established PTP1B as a critical physiologic regulator of metabolism by at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e417176bd25d65e17c459dc8bb4cd8
https://doi.org/10.1158/0008-5472.can-05-1353
https://doi.org/10.1158/0008-5472.can-05-1353