Výsledky vyhledávání - "Nadia Cristina Gomes de Morais"

The role of platelets in hemostasis and the effects of snake venom toxins on platelet function

Autor: Bruna Barbosa de Sousa, Fábio Luiz de Oliveira, Júnia de Oliveira Costa, Déborah Fernanda da Cunha Pereira, Carla Cristine Neves Mamede, Mariana Santos Matias, Nadia Cristina Gomes de Morais, Mayara Ribeiro de Queiroz

Publikováno v: Toxicon. 133:33-47

The human body has a set of physiological processes, known as hemostasis, which keeps the blood fluid and free of clots in normal vessels; in the case of vascular injury, this process induces the local formation of a hemostatic plug, preventing hemor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba54d345b998155ee92bfe60d88013e8
https://doi.org/10.1016/j.toxicon.2017.04.013

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Biochemical and functional characterization of BmooSP, a new serine protease from Bothrops moojeni snake venom

Autor: Mayara Ribeiro de Queiroz, Déborah Fernanda da Cunha Pereira, Maria Inês Homi Brandeburgo, Carla Cristine Neves Mamede, Nadia Cristina Gomes de Morais, Fábio Luiz de Oliveira, Mariana Santos Matias, Bruna Barbosa de Sousa

Publikováno v: Toxicon. 111:130-138

In this work, we describe the purification and characterization of a new serine protease enzyme from Bothrops moojeni snake venom (BmooSP). On SDS-PAGE, BmooSP was found to be a single-chain protein with an apparent molecular mass of 36,000 and 32,00

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78335889882e8f6afe5a969271fd230
https://doi.org/10.1016/j.toxicon.2016.01.055

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Isolation and characterization of moojenin, an acid-active, anticoagulant metalloproteinase from Bothrops moojeni venom

Autor: Karla de Castro Figueiredo Bordon, Fábio Luiz de Oliveira, Mayara Ribeiro de Queiroz, Carla Cristine Neves Mamede, Marcelo Emílio Beletti, Nadia Cristina Gomes de Morais, Norival A. Santos-Filho, Saulo A. Gomes-Filho, Suely Vilela Sampaio, Eliane Candiani Arantes, Kelly Cortes Fonseca

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

A fibrinogenolytic metalloproteinase from Bothrops moojeni venom, named moojenin, was purified by a combination of ion-exchange chromatography on DEAE-Sephacel and gel filtration on Sephacryl S-300. SDS-PAGE analysis indicated that moojenin consists

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58d5b500f29f01b2ed6965bf78068a1

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Comparative analysis of local effects caused by Bothrops alternatus and Bothrops moojeni snake venoms: enzymatic contributions and inflammatory modulations

Autor: Leonilda Stanziola, Déborah Fernanda da Cunha Pereira, Mariana Santos Matias, S. A. Vieira, Mayara Ribeiro de Queiroz, Bruna Barbosa de Sousa, Nadia Cristina Gomes de Morais, Carla Cristine Neves Mamede, Fábio Luiz de Oliveira

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 117

Bothropic envenomation is characterised by severe local damage caused by the toxic action of venom components and aggravated by induced inflammation. In this comparative study, the local inflammatory effects caused by the venoms of Bothrops alternatu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbcdedd6eec625e828199e15a5711ef
https://pubmed.ncbi.nlm.nih.gov/26975252

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Purification and Characterization of BmooAi: A New Toxin from Bothrops moojeni Snake Venom That Inhibits Platelet Aggregation

Autor: Rodrigo Simões-Silva, Fábio Luiz de Oliveira, Déborah Fernanda da Cunha Pereira, Carla Cristine Neves Mamede, Thaís M. Migliorini, Kelly Cortes Fonseca, Andreimar M. Soares, Mayara Ribeiro de Queiroz, Leonilda Stanziola, Leonardo A. Calderon, Nadia Cristina Gomes de Morais, Bruna Barbosa de Sousa

Publikováno v: BioMed Research International
BioMed Research International, Vol 2014 (2014)

In this paper, we describe the purification/characterization of BmooAi, a new toxin fromBothrops moojenithat inhibits platelet aggregation. The purification of BmooAi was carried out through three chromatographic steps (ion-exchange on a DEAE-Sephace

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91029f20b384b801a91ec9bb98c79dd3
http://europepmc.org/articles/PMC4058135

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Histological and ultrastructural analyses of muscle damage induced by a myotoxin isolated from Bothrops alternatus snake venom

Autor: Marcelo Emílio Beletti, Mayara Ribeiro de Queiroz, Carla Cristine Neves Mamede, Leonilda Stanziola, Fábio Luiz de Oliveira, Kelly Cortes Fonseca, Saulo Antonio Gomes Filho, Nadia Cristina Gomes de Morais

Publikováno v: Protein and peptide letters. 20(2)

Muscular necrosis is a serious consequence of Bothrops snake bites that may lead to permanent loss of tissue or function. Myonecrosis may be due to injury to blood vessels, destabilization and/or rupture of plasma membrane, and inflammatory mechanism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c628b8be2ec288713964f0aad57f8f
https://pubmed.ncbi.nlm.nih.gov/22894157

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