Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nadia Choma"'
Autor:
Raul Limjuco, Diane R. Mould, Tina Marie DeFeo, Indravadan H. Patel, Theodore Crews, Grace Milla, Nadia Choma, Stots B. Reele
Publikováno v:
Clinical Pharmacology & Therapeutics. 58:35-43
The pharmacokinetics and pharmacodynamics of midazolam and diazepam were compared after intravenous infusions of 0.03 and 0.07 mg/kg midazolam and 0.1 and 0.2 mg/kg diazepam on four separate occasions in 12 healthy male subjects in a randomized four-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a6cf470c4b778953c69ce128dcd635
https://doi.org/10.1016/0009-9236(95)90070-5
https://doi.org/10.1016/0009-9236(95)90070-5
Publikováno v:
Biomedical chromatography : BMC. 6(1)
A gas chromatographic/mass spectrometric procedure has been developed for the quantitation in human plasma of the enantiomers of rimantadine and its three hydroxylated metabolites. The assay utilized derivatization of all analytes with the optically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106528f7e9fb3070e0889199ac6964e1
https://pubmed.ncbi.nlm.nih.gov/1600368
https://pubmed.ncbi.nlm.nih.gov/1600368
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 497:147-157
A gas chromatographic-mass spectrometric procedure has been developed for the quantitation of the antiviral agent rimantadine and its meta - and para -hydroxylated metabolites in human plasma and urine. The assay utilizes an extractive pentafluoroben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3238ccb92fd887813027e2ad2d95218f
https://doi.org/10.1016/0378-4347(89)80014-3
https://doi.org/10.1016/0378-4347(89)80014-3
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 431:343-352
A gas chromatographic-mass spectrometric procedure has been developed for the quantitation in plasma and urine of the enantiomers of rimantadine, an antiviral drug effective against type A influenza. The assay utilizes derivatization with an opticall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a756c8816ca94546115d479ea867997
https://doi.org/10.1016/s0378-4347(00)83102-3
https://doi.org/10.1016/s0378-4347(00)83102-3
Publikováno v:
Journal of Pharmaceutical Sciences. 76:886-888
Twenty healthy male subjects completed an open-label randomized crossover design to assess the bioavailability of 100 mg of rimantadine HCl in tablet and syrup forms relative to an oral solution. Blood samples were drawn and rimantadine plasma concen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c87bc460c9c8978ebdc6ac09253d89
https://doi.org/10.1002/jps.2600761208
https://doi.org/10.1002/jps.2600761208
Publikováno v:
Antimicrobial Agents and Chemotherapy. 31:826-828
Twenty-four healthy adult male volunteers were randomly assigned to one of two rimantadine regimens. The 12 volunteers assigned to regimen 1 orally received a single 100-mg rimantadine tablet followed 5 days later by 100 mg of rimantadine twice a day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ce50157222e1ce01065556a236c452
https://doi.org/10.1128/aac.31.5.826
https://doi.org/10.1128/aac.31.5.826
Publikováno v:
Antimicrobial agents and chemotherapy. 33(6)
Twenty-three healthy male and female subjects received single 100-mg oral doses of rimantadine hydrochloride on two occasions in an open-label, sequential design with a 6-day washout between doses. The first dose of rimantadine was administered alone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48308f90f1cd762852d0477b23c6dbe
https://pubmed.ncbi.nlm.nih.gov/2764530
https://pubmed.ncbi.nlm.nih.gov/2764530
Autor:
Nadia Choma, Elaine K. Fukuda, W.A. Garland, Lolita C. Rodriguez, Nancy Keigher, Francis De Grazia
Publikováno v:
Biomedicalenvironmental mass spectrometry. 14(10)
A GC-MS procedure has been developed for the quantitation in plasma and urine of rimantadine, an antiviral drug effective against type A influenza. The assay utilizes selective ion monitoring, methane negative ion chemical ionization (NCI) and stable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f9f227e88130fc0153c3fd59c2f764
https://pubmed.ncbi.nlm.nih.gov/2962655
https://pubmed.ncbi.nlm.nih.gov/2962655
Publikováno v:
Journal of clinical pharmacology. 27(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af200a86336e1bb09eeecaeb9f6dcfae
https://pubmed.ncbi.nlm.nih.gov/3429689
https://pubmed.ncbi.nlm.nih.gov/3429689