Výsledky vyhledávání - "Nadia Bucurenci"

Sugar specificity of bacterial CMP kinases as revealed by crystal structures and mutagenesis of Escherichia coli enzyme

Autor: Pierre Briozzo, Thomas Bertrand, Augustin Ofiteru, Béatrice Golinelli-Pimpaneau, Nadia Bucurenci, Anne-Marie Gilles, Octavian Bârzu, Liliane Assairi, Hélène Munier-Lehmann

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2002, 315 (5), pp.1099-110. ⟨10.1006/jmbi.2001.5286⟩
Journal of Molecular Biology, 2002, 315 (5), pp.1099-110. ⟨10.1006/jmbi.2001.5286⟩

International audience; Bacterial cytidine monophosphate (CMP) kinases are characterised by an insert enlarging their CMP binding domain, and by their particular substrate specificity. Thus, both CMP and 2'-deoxy-CMP (dCMP) are good phosphate accepto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ac4d444cbef836fb829e8bc3e8aa96
https://doi.org/10.1006/jmbi.2001.5286

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Adenylate cyclases involvement in pathogenicity, a minireview

Autor: Adriana Costache, Nadia Bucurenci, Adrian Onu

Publikováno v: ResearcherID
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Cyclic AMP (cAMP), one of the most important secondary messengers, is produced by adenylate cyclase (AC) from adenosine triphosphate (ATP). AC is a widespread enzyme, being present both in prokaryotes and eukaryotes. Although they have the same enzym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::829287f7c8bb88427ee5530651dd5299
https://pubmed.ncbi.nlm.nih.gov/23947014

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Use of recombinant purified protein derivative (PPD) antigens as specific skin test for tuberculosis

Autor: Henriette, Stavri, Nadia, Bucurenci, Irina, Ulea, Adriana, Costache, Loredana, Popa, Mircea Ioan, Popa

Publikováno v: The Indian Journal of Medical Research

Background & objectives: Purified protein derivative (PPD) is currently the only available skin test reagent used worldwide for the diagnosis of tuberculosis (TB). The aim of this study was to develop a Mycobacterium tuberculosis specific skin test r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::009bb7eaf78ecc2afd5defb410685bb5
https://pubmed.ncbi.nlm.nih.gov/23287127

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Structural Properties of UMP-Kinase from Escherichia coli: Modulation of Protein Solubility by pH and UTP

Autor: Gerard Batelier, Ioan Petrescu, Octavian Bârzu, Henry H. Mantsch, Heinz Fabian, Anne-Marie Gilles, Nadia Bucurenci, Masayuki Takahashi, Lidia Serina, Witold K. Surewicz

Publikováno v: Biochemistry. 35:7003-7011

UMP-kinase from Escherichia coli, unlike the analogous enzyme from eukaryotic organisms, is an oligomeric protein subjected to complex regulatory mechanisms in which UTP and GTP act as allosteric effectors. While the enzyme has an unusually low solub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0efea8118805df2450092b3b8331ba9
https://doi.org/10.1021/bi960062v

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Regulatory mechanisms differ in UMP kinases from gram-negative and gram-positive bacteria

Autor: Adrian Onu, Octavian Bârzu, Monica Straut, Anne-Marie Gilles, Nicolae Palibroda, Nadia Bucurenci, Cécile Evrin, Neli Slavova-Azmanova, Liliane Assairi, Mihaela Ileana Ionescu

Publikováno v: The Journal of biological chemistry. 282(10)

In this work, we examined the regulation by GTP and UTP of the UMP kinases from eight bacterial species. The enzyme from Gram-positive organisms exhibited cooperative kinetics with ATP as substrate. GTP decreased this cooperativity and increased the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2491d1eea6473a4908254afadfe78f74
https://pubmed.ncbi.nlm.nih.gov/17210578

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Substitution of an Alanine Residue for Glycine 146 in TMP Kinase from Escherichia coli Is Responsible for Bacterial Hypersensitivity to Bromodeoxyuridine

Autor: Anne-Marie Gilles, Ioan Lascu, Gilbert Briand, Lise Tourneux, Nadia Bucurenci, Hiroshi Sakamoto

Publikováno v: Journal of Bacteriology. 180:4291-4293

The wild-type TMP kinases from Escherichia coli and from a strain hypersensitive to 5-bromo-2′-deoxyuridine were characterized comparatively. The mutation at codon 146 causes the substitution of an alanine residue for glycine in the enzyme, which i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb042fdc03144d037f418709541cfa8e
https://doi.org/10.1128/jb.180.16.4291-4293.1998

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Comparative study of different methods for detection of toxic and other enzymatic factors in Vibrio cholerae strains

Autor: Anca, Israil, Carmen, Balotescu, Maria, Damian, Cristina, Dinu, Nadia, Bucurenci

Publikováno v: Roumanian archives of microbiology and immunology. 63(1-2)

The purpose of this work was to characterize the toxin profile and the presence of other virulence factors involved in the pathogenesis and biology of 13 V. cholerae O1 (11 clinical cases and 2 waters) and 6 V. cholerae non O1 strains (4 clinical cas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1c6d174fa062ceaa388503a3373e945
https://pubmed.ncbi.nlm.nih.gov/16295321

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Factors associated with virulence and survival in environmental and clinical isolates of Vibrio cholerae O1 and non O1 in Romania

Autor: Anca, Israil, Carmen, Balotescu, Nadia, Bucurenci, Nadia, Năcescu, Claudia, Cedru, Cornelia, Popa, C, Ciufecu

Publikováno v: Roumanian archives of microbiology and immunology. 62(3-4)

Four hundred ninety seven strains of Vibrio cholerae selected from isolates in Romania in the last decade 1990-1999 were investigated for antibiotic resistance and for classical and putative virulence factors. V. cholerae O1 strains predominated in c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::84ffba9dab437936a6453d3cf3129e74
https://pubmed.ncbi.nlm.nih.gov/16008141

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