Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nadia B. Hassounah"'
Autor:
Kerry Anne Rogers, Pearlly Yan, Ian W. Flinn, Deborah M. Stephens, Thomas J. Kipps, Sarah M. Larson, Laura Martz, Xi Chen, Huabao Wang, Ethan Hopping, Ralf Bundschuh, Alexandra Acosta, Daniela Baldoni, Anwesha Chaudhury, Jeanne Whalen, Nadia B. Hassounah, Nina Orwitz, Janghee Woo, John C. Byrd
Publikováno v:
Cancer Research, vol 83, iss 8_Supplement
Introduction VAY736 is an afucosylated, human monoclonal antibody engineered to enhance antibody-dependent cellular cytotoxicity that targets BAFF-R+ B cells for elimination. In preclinical CLL models, VAY736 showed antileukemic activity and, when co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b058004b09c48b907cbfd85a4f211f3
https://escholarship.org/uc/item/7hp9q9d7
https://escholarship.org/uc/item/7hp9q9d7
Autor:
Kimberly M. McDermott, Thomas Bunch, Ray Nagle, Denise Roe, Colleen Fordyce, Martha Nunez, Nadia B. Hassounah
Supplemental Table S3. Hedgehog, PI3KIAKT and RAS/MAPK pathway gene signatures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac361dd69d025e3412f303955acf49b
https://doi.org/10.1158/1541-7786.22515997
https://doi.org/10.1158/1541-7786.22515997
Autor:
Kimberly M. McDermott, Thomas Bunch, Ray Nagle, Denise Roe, Colleen Fordyce, Martha Nunez, Nadia B. Hassounah
Supplemental Table S2. Descriptive Statistics for Progression-free Survival Times for the Ift20/PyMT+ Tumor Growth Study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6afc23e279fcd19d06d03451e81eaa
https://doi.org/10.1158/1541-7786.22516000.v1
https://doi.org/10.1158/1541-7786.22516000.v1
Autor:
Kimberly M. McDermott, Thomas Bunch, Ray Nagle, Denise Roe, Colleen Fordyce, Martha Nunez, Nadia B. Hassounah
Fig. 81. Inhibition of ciliogenesis is not sufficient to initiate mammary tumorigenesis. Fig. 82. Inhibition of ciliogenesis in lft20fl/fi/PyMT +glands. Fig. S3 Inhibition of ciliogenesis does not result in increased frequency of pre-malignant lesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d83616ae8abf6860b3299dcdf2b463d
https://doi.org/10.1158/1541-7786.22516006.v1
https://doi.org/10.1158/1541-7786.22516006.v1
Autor:
Kimberly M. McDermott, Thomas Bunch, Ray Nagle, Denise Roe, Colleen Fordyce, Martha Nunez, Nadia B. Hassounah
Supplemental Table S1. Descriptive Statistics for Progression-free Survival Times for the Ift88/PyMT+ Tumor Growth Study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039404ed545b9b59ecced00c2013d07f
https://doi.org/10.1158/1541-7786.22516003.v1
https://doi.org/10.1158/1541-7786.22516003.v1
Autor:
Kimberly M. McDermott, Thomas Bunch, Ray Nagle, Denise Roe, Colleen Fordyce, Martha Nunez, Nadia B. Hassounah
Primary cilia are chemosensors that play a dual role to either activate or repress Hedgehog signaling, depending on presence or absence of ligand, respectively. While inhibition of ciliogenesis has been shown to be characteristic of breast cancers, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfe950eeac487f7302202651605defc0
https://doi.org/10.1158/1541-7786.c.6541246
https://doi.org/10.1158/1541-7786.c.6541246
Autor:
Nadia B Hassounah, Ray Nagle, Kathylynn Saboda, Denise J Roe, Bruce L Dalkin, Kimberly M McDermott
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68521 (2013)
Prostate cancer is the second most commonly diagnosed cancer in men worldwide. Little is known about the role of primary cilia in preinvasive and invasive prostate cancer. However, reduced cilia expression has been observed in human cancers including
Externí odkaz:
https://doaj.org/article/24af2b32984b44aba747269cee448520
Autor:
Martha Nunez, Nadia B. Hassounah, Denise J. Roe, Kimberly M. McDermott, Colleen A. Fordyce, Thomas A. Bunch, Raymond B. Nagle
Publikováno v:
Mol Cancer Res
Primary cilia are chemosensors that play a dual role to either activate or repress Hedgehog signaling, depending on presence or absence of ligand, respectively. While inhibition of ciliogenesis has been shown to be characteristic of breast cancers, t
Autor:
Peter S. Hammerman, Ellen M. Beauchamp, Kwok-Kin Wong, Shohei Koyama, Samuel S. Freeman, Esra A. Akbay, Chandra Sekhar Pedamallu, Gordon J. Freeman, Sunil Martin, Glenn Dranoff, Nadia B. Hassounah, Nicholas C. Souders
Publikováno v:
Cancer Immunology Research. 5:A56-A56
Cancer immunotherapy has been demonstrated to be an effective strategy for the treatment of numerous tumor types. Antibodies targeting the PD1 receptor and its ligands, PDL1 and PDL2, have recently been FDA approved for multiple tumor types. Although
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 18(9)
Abnormal Hedgehog (Hh) pathway activity has been reported in many cancers, including basal cell carcinomas, medulloblastomas, rhabdomyosarcomas, glioblastomas, and breast and prostate cancers. For this reason, the Hh pathway is a flourishing area for