The pneumococcal two-component system SirRH is linked to enhanced intracellular survival of Streptococcus pneumoniae in influenza-infected pulmonary cells.

Autor: Nicolás M Reinoso-Vizcaíno, Melina B Cian, Paulo R Cortes, Nadia B Olivero, Mirelys Hernandez-Morfa, Germán E Piñas, Chandan Badapanda, Ankita Rathore, Daniel R Perez, José Echenique

Publikováno v: PLoS Pathogens, Vol 16, Iss 8, p e1008761 (2020)

The virus-bacterial synergism implicated in secondary bacterial infections caused by Streptococcus pneumoniae following infection with epidemic or pandemic influenza A virus (IAV) is well documented. However, the molecular mechanisms behind such syne

Externí odkaz: https://doaj.org/article/ab734bcf423d4b4196a38de2df195b73

Intracellular Streptococcus pneumoniae develops enhanced fluoroquinolone persistence during influenza A coinfection

Autor: Mirelys Hernandez-Morfa, Nicolas M. Reinoso-Vizcaino, Victoria E. Zappia, Nadia B. Olivero, Paulo R. Cortes, Cinthia C. Stempin, Daniel R. Perez, Jose Echenique

Publikováno v: Frontiers in Microbiology, Vol 15 (2024)

Streptococcus pneumoniae is a major pathogen responsible for severe complications in patients with prior influenza A virus (IAV) infection. We have previously demonstrated that S. pneumoniae exhibits increased intracellular survival within IAV-infect

Externí odkaz: https://doaj.org/article/b778ec33e640461a9f765373544bfdf1

Phylogenetic analysis and comparative genomics of SARS-CoV-2 from survivor and non-survivor COVID-19 patients in Cordoba, Argentina

Autor: Nadia B. Olivero, Ana S. Gonzalez-Reiche, Viviana E. Re, Gonzalo M. Castro, María B. Pisano, Paola Sicilia, María G. Barbas, Zenab Khan, Adriana van de Guchte, Jayeeta Dutta, Paulo R. Cortes, Mirelys Hernandez-Morfa, Victoria E. Zappia, Lucia Ortiz, Ginger Geiger, Daniela Rajao, Daniel R. Perez, Harm van Bakel, Jose Echenique

Publikováno v: BMC Genomics, Vol 23, Iss 1, Pp 1-11 (2022)

Abstract Background The SARS-CoV-2 virus is responsible for the COVID-19 pandemic. To better understand the evolution of SARS-CoV-2 early in the pandemic in the Province of Cordoba, Argentina, we performed a comparative genomic analysis of SARS-CoV-2

Externí odkaz: https://doaj.org/article/5315684f75fb4593b31fad858e3dc35a

The pneumococcal two-component system SirRH is linked to enhanced intracellular survival of Streptococcus pneumoniae in influenza-infected pulmonary cells

Autor: Germán E. Piñas, Ankita Rathore, Daniel R. Perez, Paulo R. Cortes, Nicolás M. Reinoso-Vizcaíno, Melina B. Cian, Chandan Badapanda, Mirelys Hernandez-Morfa, Nadia B. Olivero, José Echenique

Publikováno v: PLoS Pathogens
Repositorio Digital Universitario (UNC)
Universidad Nacional de Córdoba
instacron:UNC
PLoS Pathogens, Vol 16, Iss 8, p e1008761 (2020)

The virus-bacterial synergism implicated in secondary bacterial infections caused by Streptococcus pneumoniae following infection with epidemic or pandemic influenza A virus (IAV) is well documented. However, the molecular mechanisms behind such syne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3ef8e7723888417ca3cf7f2ac2c3b5
https://pubmed.ncbi.nlm.nih.gov/32790758

Crosstalk between the serine/threonine kinase StkP and the response regulator ComE controls the stress response and intracellular survival of Streptococcus pneumoniae

Autor: Melina B. Cian, Chandan Badapanda, Dario R. Bichara, Nubia Y. Yandar Barahona, Paulo R. Cortes, Rosario Durán, Daniel R. Perez, Nadia B. Olivero, Germán E. Piñas, Ankita Rathore, Nicolás M. Reinoso-Vizcaíno, José Echenique

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 6, p e1007118 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Streptococcus pneumoniae is an opportunistic human bacterial pathogen that usually colonizes the upper respiratory tract, but the invasion and survival mechanism in respiratory epithelial cells remains elusive. Previously, we described that acidic st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1309b1f21b2266b2bbb5a15ce25641fb
https://pubmed.ncbi.nlm.nih.gov/29883472