Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nadia Ayat"'
Autor:
Yajuan Li, Songqi Gao, Hongfa Jiang, Nadia Ayat, Victoria Laney, Calin Nicolescu, Wenyu Sun, Michael F. Tweedle, Zheng-Rong Lu
Publikováno v:
Investigative Radiology. 57:639-654
Preclinical assessments were performed according to the US Food and Drug Administration guidelines to determine the physicochemical properties, pharmacokinetics, clearance, safety, and tumor-specific magnetic resonance (MR) imaging of MT218, a peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3b5e24c179e4c8001df0482c60d713
https://doi.org/10.1097/rli.0000000000000881
https://doi.org/10.1097/rli.0000000000000881
Publikováno v:
ACS Applied Bio Materials. 5:451-458
MRI is increasingly utilized for the diagnosis of liver disease and focal liver lesions. Although liver-targeted gadolinium-based contrast agents (GBCAs) have high efficacy, there continue to be safety concerns regarding release of toxic Gd(III) ions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c212edfb2965c094abdbdfb6380a788
https://doi.org/10.1021/acsabm.1c01259
https://doi.org/10.1021/acsabm.1c01259
Autor:
Amita M. Vaidya, Ryan C. W. Hall, Ramamurthy Gopalakrishnan, Zheng-Rong Lu, Nadia Ayat, Zhanhu Sun, Da Sun, Laura M Hertz, Josef H Scheidt, Andrew L Schilb
Publikováno v:
Pharmaceutical Research. 38:1405-1418
To investigate the effectiveness of targeted ECO/miR-200c in modulating tumor microenvironment and treating triple negative breast cancer (TNBC) using non-invasive magnetic resonance molecular imaging (MRMI) of extradomain B fibronectin (EDB-FN) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e8cc7449b8f6f92de2e83187100c1af
https://doi.org/10.1007/s11095-021-03083-z
https://doi.org/10.1007/s11095-021-03083-z
Autor:
Yiqing Zhao, Zhenghe Wang, Zheng-Rong Lu, Amita M. Vaidya, Megan N. Buford, Nadia Ayat, Hannah Gilmore, Aman Shankardass, Helen Wang
Publikováno v:
Theranostics
Antineoplastic resistance represents a multifaceted challenge for cancer therapy and diagnostics. Extensive molecular heterogeneity, even within neoplasms of the same type, can elicit distinct outcomes of administering therapeutic pressures, frequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006ecb4bb8c683d0db974a1fc321eb39
http://europepmc.org/articles/PMC7532678
http://europepmc.org/articles/PMC7532678
Publikováno v:
Cancer Communications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d145df209f1c1300c893bb84ac1400
https://doi.org/10.1002/cac2.12011
https://doi.org/10.1002/cac2.12011
Autor:
Da Sun, Andrew L Schilb, Ryan C. W. Hall, Michelle Yin, Zheng-Rong Lu, Josef H Scheidt, X. Liu, Nadia Ayat, Zhanhu Sun, Amita M. Vaidya
Publikováno v:
Nucleic Acid Ther
Nanoparticle based siRNA formulations often suffer from aggregation and loss of function during storage. We in this study report a frozen targeted RGD-polyethylene glycol (PEG)-ECO/siβ3 nanoparticle formulation with a prolonged shelf life and preser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0134b57a72294bfd33eacb2978b416
https://doi.org/10.1089/nat.2019.0784
https://doi.org/10.1089/nat.2019.0784
Publikováno v:
Cancers
Cancers, Vol 12, Iss 3260, p 3260 (2020)
Volume 12
Issue 11
Cancers, Vol 12, Iss 3260, p 3260 (2020)
Volume 12
Issue 11
Radiation therapy is a mainstay in the standard of care for glioblastoma (GBM), thus inhibiting the DNA damage response (DDR) is a major strategy to improve radiation response and therapeutic outcomes. Small interfering RNA (siRNA) therapy holds imme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4507959a1b29c570c0a9cc08b7f25f9a
http://europepmc.org/articles/PMC7694254
http://europepmc.org/articles/PMC7694254
Publikováno v:
Advanced healthcare materials. 10(5)
RNA interference (RNAi) is a promising technology to regulate oncogenes for treating cancer. The primary limitation of siRNA for clinical application is the safe and efficacious delivery of therapeutic siRNA into target cells. Lipid-based delivery sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f82e2f6acce0a115567f5a515116c7
https://pubmed.ncbi.nlm.nih.gov/33615743
https://pubmed.ncbi.nlm.nih.gov/33615743
Autor:
Ivan J. Stojanov, Dan Ma, Ryan C. W. Hall, Zheng-Rong Lu, Nadia Ayat, Amita M. Vaidya, Anita Aminoshariae, Peter Qiao
Publikováno v:
Mol Imaging Biol
PURPOSE: Oral squamous cell carcinoma (OSCC) has not seen a substantial improvement in patient survival despite therapeutic advances, making accurate detection and characterization of the disease a clinical priority. Here, we aim to demonstrate the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ef76da3654058b2e507fe99174fc47
https://pubmed.ncbi.nlm.nih.gov/32789648
https://pubmed.ncbi.nlm.nih.gov/32789648
Autor:
Da Sun, Zheng Han, Rui Xin, Hongfa Jiang, Amirreza Naderi, Zhanhu Sun, Nadia Ayat, Zheng-Rong Lu, Andrew L Schilb, Peter Qiao, Amita M. Vaidya
Publikováno v:
Bioconjugate Chemistry
CRISPR/Cas9 system is a promising approach for gene editing in gene therapy. Effective gene editing requires safe and efficient delivery of CRISPR/Cas9 system in target cells. Several new multifunctional pH-sensitive amino lipids were designed and sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ce8a4457b0382d1d751b3333dc4fbd
http://europepmc.org/articles/PMC6429435
http://europepmc.org/articles/PMC6429435