Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Nadia Messaddeq"'
Autor:
Kamar Ghaibour, Mélanie Schuh, Sirine Souali‐Crespo, Céline Chambon, Anouk Charlot, Joe Rizk, Daniela Rovito, Anna‐Isavella Rerra, Qingshuang Cai, Nadia Messaddeq, Joffrey Zoll, Delphine Duteil, Daniel Metzger
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1707-1720 (2023)
Abstract Background Androgens are anabolic steroid hormones that exert their function by binding to the androgen receptor (AR). We have previously established that AR deficiency in limb muscles impairs sarcomere myofibrillar organization and decrease
Externí odkaz:
https://doaj.org/article/f4c9e5d5274241379cf451254cce573e
Autor:
Alphonse Rodrigue DJIBOUNE, Nicolas Anton, Sidy Mouhamed Dieng, Papa Mady Sy, Diouf Diouf, Gora Mbaye, Mamadou Soumboundou, Said Ennahar, Nadia Messaddeq, Thierry Vandamme, Mounibe Diarra
Publikováno v:
Journal Africain de Technologie Pharmaceutique et Biopharmacie, Vol 2, Iss 3 (2023)
Introduction : Le but de l’étude était de développer des hydrogels oraux à base de chitosane pH- sensibles, capables de libérer le phénobarbital dans l'intestin grêle du nouveau-né. Ces hydrogels amélioreraient sa biodisponibilité et son
Externí odkaz:
https://doaj.org/article/2c917983d70d47f4aba81f2b2a0be3ed
Autor:
Anna Niewiadomska-Cimicka, Antoine Hache, Stéphanie Le Gras, Céline Keime, Tao Ye, Aurelie Eisenmann, Imen Harichane, Michel J. Roux, Nadia Messaddeq, Emmanuelle Clérin, Thierry Léveillard, Yvon Trottier
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-23 (2022)
Abstract Background Spinocerebellar ataxia type 7 (SCA7) is a neurodegenerative disorder that primarily affects the cerebellum and retina. SCA7 is caused by a polyglutamine expansion in the ATXN7 protein, a subunit of the transcriptional coactivator
Externí odkaz:
https://doaj.org/article/fe31de53419248fabcb1c3dfd9b45723
Autor:
Raquel Gómez-Oca, Evelina Edelweiss, Sarah Djeddi, Mathias Gerbier, Xènia Massana-Muñoz, Mustapha Oulad-Abdelghani, Corinne Crucifix, Coralie Spiegelhalter, Nadia Messaddeq, Pierre Poussin-Courmontagne, Pascale Koebel, Belinda S. Cowling, Jocelyn Laporte
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Dynamin 2 is a large GTPase linked to several human diseases. Here, Gómez-Oca et al. investigate the functions of muscle dynamin 2 isoforms and provide insights into their differential implication in centronuclear myopathy pathogenesis and treatment
Externí odkaz:
https://doaj.org/article/684832f01d92429ca6b407420e59785d
Autor:
Soumajit Mukherjee, Zuzana Bytesnikova, Sophie Martin, Pavel Svec, Andrea Ridoskova, Jana Pekarkova, Cendrine Seguin, Jean‐Luc Weickert, Nadia Messaddeq, Yves Mély, Lukas Richtera, Halina Anton, Vojtech Adam
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 6, Pp n/a-n/a (2023)
Abstract Graphene‐based 2D nanomaterials exhibit unique physicochemical, electric, and optical properties that facilitate applications in a wide range of fields including material science, electronics, and biotechnology. Recent studies have shown t
Externí odkaz:
https://doaj.org/article/23d7cc83003744078f6110284795e51d
Autor:
Marion Ferren, Valérie Favède, Didier Decimo, Mathieu Iampietro, Nicole A. P. Lieberman, Jean-Luc Weickert, Rodolphe Pelissier, Magalie Mazelier, Olivier Terrier, Anne Moscona, Matteo Porotto, Alexander L. Greninger, Nadia Messaddeq, Branka Horvat, Cyrille Mathieu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Here, Ferren et al. isolate Syrian hamster brainstem and lung tissue to establish ex vivo culture systems to study SARS-CoV-2 local viral tropism, immune response and tissue pathology. Further, they provide evidence that these systems can be used for
Externí odkaz:
https://doaj.org/article/d0f36ce0ff77494588238708b9573bc8
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 120-138 (2020)
Friedreich ataxia (FA) is currently an incurable inherited mitochondrial disease caused by reduced levels of frataxin (FXN). Cardiac dysfunction is the main cause of premature death in FA. Adeno-associated virus (AAV)-mediated gene therapy constitute
Externí odkaz:
https://doaj.org/article/fa54e2a198ec448e8bab56a06c3b3146
Autor:
Renee Wei-Yan Chow, Hajime Fukui, Wei Xuan Chan, Kok Soon Justin Tan, Stéphane Roth, Anne-Laure Duchemin, Nadia Messaddeq, Hiroyuki Nakajima, Fei Liu, Nathalie Faggianelli-Conrozier, Andrey S Klymchenko, Yap Choon Hwai, Naoki Mochizuki, Julien Vermot
Publikováno v:
PLoS Biology, Vol 20, Iss 1, p e3001505 (2022)
In the clinic, most cases of congenital heart valve defects are thought to arise through errors that occur after the endothelial-mesenchymal transition (EndoMT) stage of valve development. Although mechanical forces caused by heartbeat are essential
Externí odkaz:
https://doaj.org/article/f8b10f232dab4b68966608ab62009b85
Autor:
Hichem Tasfaout, Suzie Buono, Shuling Guo, Christine Kretz, Nadia Messaddeq, Sheri Booten, Sarah Greenlee, Brett P. Monia, Belinda S. Cowling, Jocelyn Laporte
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
X-linked myotubular myopathy is caused by mutations in the gene coding for myotubularin 1, and is characterized by overexpression of dynamin 2. Here the authors develop antisense oligonucleotides to dynamin 2, and show that systemic injection leads t
Externí odkaz:
https://doaj.org/article/ea5ef61a87bf47839d28720d6a64f759
Autor:
Lena Kristina Beilschmidt, Sandrine Ollagnier de Choudens, Marjorie Fournier, Ioannis Sanakis, Marc-André Hograindleur, Martin Clémancey, Geneviève Blondin, Stéphane Schmucker, Aurélie Eisenmann, Amélie Weiss, Pascale Koebel, Nadia Messaddeq, Hélène Puccio, Alain Martelli
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The mitochondrial proteins ISCA1 and ISCA2 form a complex that is involved in the biogenesis of Fe–S clusters. Here the authors report that ISCA1 and ISCA2 interact differently with proteins of the Fe–S machinery and that under certain conditions
Externí odkaz:
https://doaj.org/article/067e79be2eb44b3496a3b8fba496a36b