Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Nadhim, Bayatti"'
Autor:
Rawshan Choudhury, Nadhim Bayatti, Richard Scharff, Ewa Szula, Viranga Tilakaratna, Maja Søberg Udsen, Selina McHarg, Janet A. Askari, Martin J. Humphries, Paul N. Bishop, Simon J. Clark
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Retinal pigment epithelial (RPE) cells that underlie the neurosensory retina are essential for the maintenance of photoreceptor cells and hence vision. Interactions between the RPE and their basement membrane, i.e. the inner layer of Bruch
Externí odkaz:
https://doaj.org/article/744e5ccb41c64bcf9d0d0a1eaadb8a8c
Autor:
Valentina Cipriani, Laura Lorés-Motta, Fan He, Dina Fathalla, Viranga Tilakaratna, Selina McHarg, Nadhim Bayatti, İlhan E. Acar, Carel B. Hoyng, Sascha Fauser, Anthony T. Moore, John R. W. Yates, Eiko K. de Jong, B. Paul Morgan, Anneke I. den Hollander, Paul N. Bishop, Simon J. Clark
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
A locus on chromosome 1 encompassing the CFHR genes is highly associated with AMD risk. Here, Cipriani and colleagues investigate the role of CFHR4, encoding FHR-4, and demonstrate a relationship between AMD risk, circulating FHR-4 levels and genetic
Externí odkaz:
https://doaj.org/article/0b0f1261bc8d49669412ef574f2fe536
Autor:
Selina Mcharg, Laura Booth, Rahat Perveen, Isabel Riba Garcia, Nicole Brace, Nadhim Bayatti, Panagiotis I. Sergouniotis, Alexander M. Phillips, Anthony J. Day, Graeme C. M. Black, Simon J. Clark, Andrew W. Dowsey, Richard D. Unwin, Paul N. Bishop
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Age-related macular degeneration (AMD) is a leading cause of visual loss. It has a strong genetic basis, and common haplotypes on chromosome (Chr) 1 (CFH Y402H variant) and on Chr10 (near HTRA1/ARMS2) contribute the most risk. Little is known about t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9974eae92af93fc4602c96f95d27da5f
http://livrepository.liverpool.ac.uk/3156385/1/547377_2_merged_1650304113.pdf
http://livrepository.liverpool.ac.uk/3156385/1/547377_2_merged_1650304113.pdf
Autor:
Nadhim Bayatti, Johnathan Cooper-Knock, Joanna J Bury, Matthew Wyles, Paul R Heath, Janine Kirby, Pamela J Shaw
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87508 (2014)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes death within a mean of 2-3 years from symptom onset. There is no diagnostic test and the delay from symptom onset to diagnosis averages 12 months. The identification of pr
Externí odkaz:
https://doaj.org/article/7fcadda720654c26bd2a01d5ec6231cc
Autor:
Paul R. Heath, Cecilia Garlanda, Andrea Malaspina, P. Nigel Leigh, William Camu, Henrik Zetterberg, Christophe Masseguin, Gilbert Bensimon, Ilaria Giovannelli, Jean-Luc Veyrune, Abigail Brown, Ulf Andreasson, Dennis Wang, Nadhim Bayatti, Pamela J. Shaw, Massimo Locati, Ammar Al-Chalabi, Christine Payan, Safa Saker, Janine Kirby, Nicolas Pageot, John De Vos, Carey M. Suehs, Marius Mickunas, Raul Juntas-Morales, Timothy Tree
Publikováno v:
Brain Communications
Brain Communications, Oxford University Press on behalf of the Guarantors of Brain, 2021, 3 (3), ⟨10.1093/braincomms/fcab141⟩
Brain Communications, Oxford University Press on behalf of the Guarantors of Brain, 2021, 3 (3), ⟨10.1093/braincomms/fcab141⟩
Amyotrophic lateral sclerosis is a fatal neurodegenerative disease causing upper and lower motor neuron loss and currently no effective disease-modifying treatment is available. A pathological feature of this disease is neuroinflammation, a mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac2b5c9bc7df7be6fbd4be0a5b6e9d3
https://pubmed.ncbi.nlm.nih.gov/34409288
https://pubmed.ncbi.nlm.nih.gov/34409288
Autor:
Martin J. Humphries, Paul N. Bishop, Nadhim Bayatti, Maja Søberg Udsen, Rawshan Choudhury, Viranga Tilakaratna, Selina McHarg, Richard Scharff, Ewa Szula, Simon J. Clark, Janet A. Askari
Publikováno v:
Scientific Reports
Choudhury, R, Bayatti, N, Scharff, R, Szula, E, Tilakaratna, V, Udsen, M, Mcharg, S, Askari, J, Humphries, M J, Bishop, P & Clark, S 2021, ' FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress ', Scientific Reports, vol. 11, no. 1, 14175 . https://doi.org/10.1038/s41598-021-93708-5
Choudhury, R, Bayatti, N, Scharff, R, Szula, E, Tilakaratna, V, Udsen, M S, McHarg, S, Askari, J A, Humphries, M J, Bishop, P N & Clark, S J 2021, ' FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress ', Scientific Reports, vol. 11, 14175 . https://doi.org/10.1038/s41598-021-93708-5
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Choudhury, R, Bayatti, N, Scharff, R, Szula, E, Tilakaratna, V, Udsen, M, Mcharg, S, Askari, J, Humphries, M J, Bishop, P & Clark, S 2021, ' FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress ', Scientific Reports, vol. 11, no. 1, 14175 . https://doi.org/10.1038/s41598-021-93708-5
Choudhury, R, Bayatti, N, Scharff, R, Szula, E, Tilakaratna, V, Udsen, M S, McHarg, S, Askari, J A, Humphries, M J, Bishop, P N & Clark, S J 2021, ' FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress ', Scientific Reports, vol. 11, 14175 . https://doi.org/10.1038/s41598-021-93708-5
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Retinal pigment epithelial (RPE) cells that underlie the neurosensory retina are essential for the maintenance of photoreceptor cells and hence vision. Interactions between the RPE and their basement membrane, i.e. the inner layer of Bruch’s membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd44c6c515f5cf3e410767874f2acb8
https://pubmed.ncbi.nlm.nih.gov/34239032
https://pubmed.ncbi.nlm.nih.gov/34239032
Autor:
Fan He, Eiko K. de Jong, Laura Lorés-Motta, John R.W. Yates, Sascha Fauser, Anthony T. Moore, B. Paul Morgan, Nadhim Bayatti, Selina McHarg, Ilhan Erkin Acar, Simon J. Clark, Anneke I. den Hollander, Carel B. Hoyng, Paul N. Bishop, Valentina Cipriani, Dina Fathalla, Viranga Tilakaratna
Publikováno v:
Nature Communications
Nature Communications, 11
Cipriani, V, Lores-Motta, L, He, F, Fathalla, D, Tilakaratna, V, Mcharg, S, Bayatti, N, Acar, I E, Hyong, C B, Fauser, S, Moore, A T, Yates, J R W, de Jong, E K, Morgan, B P, den Hollander, A I, Bishop, P & Clark, S 2020, ' Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration ', Nature Communications, vol. 11, no. 1, 778, pp. 778 . https://doi.org/10.1038/s41467-020-14499-3
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature communications, vol 11, iss 1
Nature Communications, 11, 1
Nature Communications, 11
Cipriani, V, Lores-Motta, L, He, F, Fathalla, D, Tilakaratna, V, Mcharg, S, Bayatti, N, Acar, I E, Hyong, C B, Fauser, S, Moore, A T, Yates, J R W, de Jong, E K, Morgan, B P, den Hollander, A I, Bishop, P & Clark, S 2020, ' Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration ', Nature Communications, vol. 11, no. 1, 778, pp. 778 . https://doi.org/10.1038/s41467-020-14499-3
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature communications, vol 11, iss 1
Nature Communications, 11, 1
Age-related macular degeneration (AMD) is a leading cause of blindness. Genetic variants at the chromosome 1q31.3 encompassing the complement factor H (CFH, FH) and CFH related genes (CFHR1-5) are major determinants of AMD susceptibility, but their m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cc8d9a95cdbfac23be641800dac97a
http://europepmc.org/articles/PMC7005798
http://europepmc.org/articles/PMC7005798
Publikováno v:
Journal of Neurochemistry. 133:352-367
Oxidative stress is an early hallmark in neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. However, the critical biochemical effector mechanisms of oxidative neurotoxicity have remained surprisingly elusive. In screening vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb8a66dd3b117581052908df8f18b70
https://doi.org/10.1111/jnc.12987
https://doi.org/10.1111/jnc.12987
Publikováno v:
Cerebral Cortex (New York, NY)
GABAergic interneurons are crucial to controlling the excitability and responsiveness of cortical circuitry. Their developmental origin may differ between rodents and human. We have demonstrated the expression of 12 GABAergic interneuron-associated g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bb30c6314961860a804b1fc2c2fb88
https://doi.org/10.1093/cercor/bht254
https://doi.org/10.1093/cercor/bht254
Autor:
Susan Lindsay, Gavin J. Clowry, Hamad Ali, Andrew J. Trevelyan, Nadhim Bayatti, Nicolas Forraz, Christina Basford, Bui Kar Ip, Marcin Jurga, Colin McGuckin, Saba Habibollah, Sajjad Ahmad
Publikováno v:
Stem Cell Reviews and Reports. 8:210-223
Neurogenesis of excitatory neurons in the developing human cerebral neocortex is a complex and dynamic set of processes and the exact mechanisms controlling the specification of human neocortical neuron subtypes are poorly understood due to lack of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f4fd1b17e23ad6535baccde4c4e754
https://doi.org/10.1007/s12015-011-9287-x
https://doi.org/10.1007/s12015-011-9287-x