Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nadhi Thekkek"'
Publikováno v:
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine. 78:894-904
Esophageal adenocarcinoma carries a poor prognosis, as it typically presents at a late stage. Thus, a major research priority is the development of novel diagnostic-imaging strategies that can detect neoplastic lesions earlier and more accurately tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a108f867bfe2ad5d8f21fec2450b216d
https://doi.org/10.1002/msj.20304
https://doi.org/10.1002/msj.20304
Autor:
Rebecca Richards-Kortum, Nadhi Thekkek
Publikováno v:
Nature Reviews Cancer. 8:725-731
Cervical cancer is the leading cause of cancer death for women in developing countries1. Optical technologies can improve the accuracy and availability of cervical cancer screening. For example, battery-powered digital cameras can obtain multi-spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d1e5499698b6d174f2138cb14e3ea9
https://doi.org/10.1038/nrc2462
https://doi.org/10.1038/nrc2462
Publikováno v:
Small. 2:1412-1417
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e519b129c128d2f061268cf4c6ca91
https://doi.org/10.1002/smll.200600218
https://doi.org/10.1002/smll.200600218
Autor:
Paul Peng, Neil Parikh, Rebecca Richards-Kortum, Alexandros D. Polydorides, Sharmila Anandasabapathy, Michelle H. Lee, Daniel P. Perl, Shannon Chang, Nadhi Thekkek, Josephine Mitcham
Publikováno v:
Journal of Visualized Experiments.
The ability to differentiate benign metaplasia in Barrett’s Esophagus (BE) from neoplasia in vivo remains difficult as both tissue types can be flat and indistinguishable with white light imaging alone. As a result, a modality that highlights gland
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d780774d14d69f6ed16d34920300a86
https://doi.org/10.3791/50992
https://doi.org/10.3791/50992
Autor:
Mark C. Pierce, Michelle H. Lee, Alexandros D. Polydorides, Raja M. Flores, Sharmila Anandasabapathy, Rebecca Richards-Kortum, Nadhi Thekkek
A modular video endoscope is developed and tested to allow imaging in different modalities. This system incorporates white light imaging (WLI), cross-polarized imaging (CPI), and vital-dye fluorescence imaging (VFI), using interchangeable filter modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa794ff306cd823f07223148d7ae13e
https://europepmc.org/articles/PMC3561596/
https://europepmc.org/articles/PMC3561596/
Autor:
Sharmila Anandasabapathy, Alexandros D. Polydorides, Manoop S. Bhutani, Rebecca Richards-Kortum, Dipen M. Maru, Nadhi Thekkek
Publikováno v:
Technology in Cancer Research & Treatment
The availability of confocal endomicroscopy motivates the development of optical contrast agents that can delineate the morphologic and metabolic features of gastrointestinal neoplasia. This study evaluates 2-NBDG, a fluorescent deoxyglucose, the upt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b133571ecd785c1703581262fae1e517
https://pubmed.ncbi.nlm.nih.gov/21895028
https://pubmed.ncbi.nlm.nih.gov/21895028
Autor:
Noam Harpaz, Michael T. Harris, Dipen M. Maru, Alexandros D. Polydorides, Sanghyun A. Kim, Timothy J. Muldoon, Sharmila Anandasabapathy, Spiros P. Hiotis, Rebecca Richards-Kortum, Wayne Hofstettor, Nadhi Thekkek, Alex J. Ky
Publikováno v:
Gastrointestinal endoscopy. 75(4)
Background Confocal endomicroscopy has revolutionized endoscopy by offering subcellular images of the GI epithelium; however, the field of view is limited. Multiscale endoscopy platforms that use widefield imaging are needed to better direct the plac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f90b9858e89fcc76ff827896020962
https://pubmed.ncbi.nlm.nih.gov/22301343
https://pubmed.ncbi.nlm.nih.gov/22301343
Autor:
Sharmila Anandasabapathy, Mark C. Pierce, Peter K Thompson, Kelsey Rosbach, Rebecca Richards-Kortum, Nadhi Thekkek, Ann M. Gillenwater, Raymond Kaufman
Publikováno v:
Biomedical Optics and 3-D Imaging.
We have developed a high-resolution fluorescence microendoscope capable of imaging sub-cellular morphology in vivo, in real-time. We report our latest results in clinical studies for early cancer detection in the cervix, oral cavity, and esophagus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a2f699832511724f9634286a4102d50
https://doi.org/10.1364/biomed.2010.btud93
https://doi.org/10.1364/biomed.2010.btud93
Autor:
Noam Harpaz, Timothy J. Muldoon, Alexandros D. Polydorides, Rebecca Richards-Kortum, Sharmila Anandasabapathy, Dipen M. Maru, Nadhi Thekkek
Publikováno v:
Biomedical Optics and 3-D Imaging.
This ex vivo study evaluates widefield and high-resolution fluorescence imaging with vital-dye enhancement to improve endoscopic evaluation of metaplasia, dysplasia, and cancer in the gastrointestinal tract. Differences in epithelial features were ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d79b55e03f9278b61803eb9182894bef
https://doi.org/10.1364/biomed.2010.btud61
https://doi.org/10.1364/biomed.2010.btud61
Autor:
Bertha Valle, Rebecca Richards-Kortum, Dipen M. Maru, Sharmila Anandasabapathy, Nadhi Thekkek
Publikováno v:
Biomedical Optics.
Esophageal pre-cancer biomarkers can be optically detected in tissue using confocal microscopy and specific stains. Developing and characterizing these optical biomarkers ex vivo is necessary to be able to detect them in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d7c4afdb46c6e36d05ac7df9785ff74
https://doi.org/10.1364/biomed.2008.btud3
https://doi.org/10.1364/biomed.2008.btud3