Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nadezhda Zhigalova"'
Autor:
Artem V. Artemov, Nadezhda Zhigalova, Svetlana Zhenilo, Alexander M. Mazur, Egor B. Prokhortchouk
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract VHL inactivation is a key oncogenic event for renal carcinomas. In normoxia, VHL suppresses HIF1a-mediated transcriptional response, which is characteristic to hypoxia. It has previously been shown that hypoxic conditions inhibit TET-depende
Externí odkaz:
https://doaj.org/article/15befa2463bd4422a26c6f55bc7ff062
Publikováno v:
F1000Research, Vol 4 (2015)
Human cancer cells are subjected to hypoxic conditions in many tumours. Hypoxia causes alterations in the glycolytic pathway activation through stabilization of hypoxia-inducible factor 1. Currently, two approaches are commonly used to model hypoxia:
Externí odkaz:
https://doaj.org/article/1300d6cc51d9486e844728b9e98ae75c
Cytoskeletal Protein Zyxin Inhibits the Activity of Genes Responsible for Embryonic Stem Cell Status
Autor:
Nadezhda Zhigalova, Fatima K. Gyoeva, Dmitry B. Staroverov, Eugeny E. Оrlov, Natalia Y. Martynova, Andrey G. Zaraisky, Arina G. Shokhina, Fedor M. Eroshkin, Elena A. Parshina, Vsevolod V. Belousov, Egor Prokhortchouk
Publikováno v:
Cell Reports, Vol 33, Iss 7, Pp 108396-(2020)
Summary: Zyxin is a cytoskeletal LIM-domain protein that regulates actin cytoskeleton assembly and gene expression. In the present work, we find that zyxin downregulation in Xenopus laevis embryos reduces the expression of numerous genes that regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528db41d6a3e393957bcbc6ae617fc94
https://doi.org/10.2139/ssrn.3554017
https://doi.org/10.2139/ssrn.3554017
Autor:
Alexey Starshin, Svetlana Zhenilo, Egor Prokhortchouk, Alexander Mazur, Fedor S. Sharko, Nadezhda Zhigalova, Galina Filonova, Darya Kaplun, Kristina Gainova
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7587, p 7587 (2021)
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7587, p 7587 (2021)
Volume 22
Issue 14
Gain and loss of DNA methylation in cells is a dynamic process that tends to achieve an equilibrium. Many factors are involved in maintaining the balance between DNA methylation and demethylation. Previously, it was shown that methyl-DNA protein Kais
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c886b4d68dfdd7fac25515fac653a8f
https://doi.org/10.3390/ijms22147587
https://doi.org/10.3390/ijms22147587
Publikováno v:
Молекулярная биология. :836-840
Uncontrolled growth in the cell mass of malignant tumors induces intensive angiogenesis. However, the demands of the cancer cells for nutrients and oxygen remain only partially met. Hypoxia is a process that accompanies malignant transformation and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04166940011e89fadee5e6481dc157f6
https://doi.org/10.7868/s0026898417050111
https://doi.org/10.7868/s0026898417050111
Autor:
Ekaterina A. Litvinova, Daria Kaplun, I. E. Deyev, Egor Prokhortchouk, Svetlana Zhenilo, Nadezhda Zhigalova, Alexander Mazur, Alexey E. Sokolov
Kaiso is a member of the BTB/POZ zinc finger family, which is involved in cancer progression, cell cycle control, apoptosis, and WNT signaling. Depending on promoter context, it may function as either a transcriptional repressor or activator. Previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073e4824be6d3f0d3f33af63a1612f80
https://europepmc.org/articles/PMC6219498/
https://europepmc.org/articles/PMC6219498/
Publikováno v:
Molecular Biology. 49:322-325
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcca25b8ba516de93a18dc753ab4460d
https://doi.org/10.1134/s002689331502017x
https://doi.org/10.1134/s002689331502017x
Autor:
Egor Borisovich Prokhorchouk, Valeriya Sergeevna Shumskaya, Nadezhda Zhigalova, Anna Valerievna Prokhorchouk
Publikováno v:
Histochemistry and Cell Biology. 143:29-43
The Kaiso protein was originally described as a BTB/POZ zinc-finger transcription factor and a p120-catenin-binding partner. It is a DNA methylation-dependent transcriptional repressor, but its biological role in mice is still unknown. Here, we chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb6776fad06b5af3d6b8d2533140b70
https://doi.org/10.1007/s00418-014-1261-7
https://doi.org/10.1007/s00418-014-1261-7
Autor:
Nadezhda Zhigalova, Alexander M. Mazur, Egor Prokhortchouk, Svetlana Zhenilo, Artem V. Artemov
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
VHL inactivation is a key oncogenic event for renal carcinomas. In normoxia, VHL suppresses HIF1a-mediated transcriptional response, which is characteristic to hypoxia. It has previously been shown that hypoxic conditions inhibit TET-dependent hydrox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d98795eb110ec1580336330bbc59ca1
Autor:
A. A. Ovsepyan, G. B. Telegin, T E Sviridova, Egor Prokhortchouk, U I Buziashvili, D N Panchenkov, Matskeplishvili St, Nadezhda Zhigalova, E P Golubev, Konstantin G. Skryabin
Publikováno v:
Acta Naturae
Myocardial infarction is one of the most serious and widespread diseases in the world. In this work, a minimally invasive method for simulating myocardial infarction in mice is described in the Russian Federation for the very first time; the procedur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237d49b6876c3c34755282dd03b98888
https://doi.org/10.32607/20758251-2011-3-1-107-115
https://doi.org/10.32607/20758251-2011-3-1-107-115