Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Nadezhda T, Doncheva"'
Autor:
Tanveer Singh Batth, Marie Locard-Paulet, Nadezhda T. Doncheva, Blanca Lopez Mendez, Lars Juhl Jensen, Jesper Velgaard Olsen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Proteins are the primary targets of almost all small molecule drugs. However, even the most selectively designed drugs can potentially target several unknown proteins. Identification of potential drug targets can facilitate design of new dru
Externí odkaz:
https://doaj.org/article/596874fe32fc4c529293f9473a9ae2e0
Autor:
Giulia I. Corsi, Veerendra P. Gadekar, Henriette Haukedal, Nadezhda T. Doncheva, Christian Anthon, Sheetal Ambardar, Dasaradhi Palakodeti, Poul Hyttel, Kristine Freude, Stefan E. Seemann, Jan Gorodkin
Publikováno v:
Neurobiology of Disease, Vol 178, Iss , Pp 105980- (2023)
Alzheimer's disease (AD) is a progressive and irreversible brain disorder, which can occur either sporadically, due to a complex combination of environmental, genetic, and epigenetic factors, or because of rare genetic variants in specific genes (fam
Externí odkaz:
https://doaj.org/article/ee81fe4b9b794196a8c7ff4609458c32
Autor:
Henriette Haukedal, Giulia I. Corsi, Veerendra P. Gadekar, Nadezhda T. Doncheva, Shekhar Kedia, Noortje de Haan, Abinaya Chandrasekaran, Pia Jensen, Pernille Schiønning, Sarah Vallin, Frederik Ravnkilde Marlet, Anna Poon, Carlota Pires, Fawzi Khoder Agha, Hans H. Wandall, Susanna Cirera, Anja Hviid Simonsen, Troels Tolstrup Nielsen, Jørgen Erik Nielsen, Poul Hyttel, Ravi Muddashetty, Blanca I. Aldana, Jan Gorodkin, Deepak Nair, Morten Meyer, Martin Røssel Larsen, Kristine Freude
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Alzheimer’s disease (AD) is the most common cause of dementia, with no current cure. Consequently, alternative approaches focusing on early pathological events in specific neuronal populations, besides targeting the well-studied amyloid beta (Aβ)
Externí odkaz:
https://doaj.org/article/4d6bdc2e3ad742debbe8defab51f61f4
Autor:
Reza Yarani, Oana Palasca, Nadezhda T. Doncheva, Christian Anthon, Bartosz Pilecki, Cecilie A. S. Svane, Aashiq H. Mirza, Thomas Litman, Uffe Holmskov, Claus H. Bang-Berthelsen, Mogens Vilien, Lars J. Jensen, Jan Gorodkin, Flemming Pociot
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
Background: Ulcerative colitis (UC) is a disorder with unknown etiology, and animal models play an essential role in studying its molecular pathophysiology. Here, we aim to identify common conserved pathological UC-related gene expression signatures
Externí odkaz:
https://doaj.org/article/715c5209dfe143fea179b0e716c6022a
Autor:
Adrian S. Geissler, Line D. Poulsen, Nadezhda T. Doncheva, Christian Anthon, Stefan E. Seemann, Enrique González-Tortuero, Anne Breüner, Lars J. Jensen, Carsten Hjort, Jeppe Vinther, Jan Gorodkin
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The production of the alpha-amylase (AMY) enzyme in Bacillus subtilis at a high rate leads to the accumulation of unfolded AMY, which causes secretion stress. The over-expression of the PrsA chaperone aids enzyme folding and reduces stress. To identi
Externí odkaz:
https://doaj.org/article/a60d2c584eda4fc5adb17a7740bf7e63
Autor:
Reza Yarani, Ali Shojaeian, Oana Palasca, Nadezhda T. Doncheva, Lars Juhl Jensen, Jan Gorodkin, Flemming Pociot
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Differential microRNA (miRNA or miR) regulation is linked to the development and progress of many diseases, including inflammatory bowel disease (IBD). It is well-established that miRNAs are involved in the differentiation, maturation, and functional
Externí odkaz:
https://doaj.org/article/981e58615b4d4e998a483aaa98d7b0dd
Autor:
Christopher Ashwood, Wout Bittremieux, Eric W. Deutsch, Nadezhda T. Doncheva, Viktoria Dorfer, Ralf Gabriels, Vladimir Gorshkov, Surya Gupta, Andrew R. Jones, Lukas Käll, Dominik Kopczynski, Lydie Lane, Ludwig Lautenbacher, Marc Legeay, Marie Locard-Paulet, Bart Mesuere, Yasset Perez-Riverol, Eugen Netz, Julianus Pfeuffer, Timo Sachsenberg, Renee Salz, Patroklos Samaras, Henning Schiebenhoefer, Tobias Schmidt, Veit Schwämmle, Alessio Soggiu, Julian Uszkoreit, Tim Van Den Bossche, Bart Van Puyvelde, Joeri Van Strien, Pieter Verschaffelt, Henry Webel, Sander Willems
Publikováno v:
EuPA Open Proteomics, Vol 24, Iss , Pp 1-6 (2020)
The 2020 European Bioinformatics Community for Mass Spectrometry (EuBIC-MS) Developers’ meeting was held from January 13th to January 17th 2020 in Nyborg, Denmark. Among the participants were scientists as well as developers working in the field of
Externí odkaz:
https://doaj.org/article/89b6c3b9a90f4f73b2e9b77d5a0186f4
Autor:
Tomas Bastys, Vytautas Gapsys, Hauke Walter, Eva Heger, Nadezhda T. Doncheva, Rolf Kaiser, Bert L. de Groot, Olga V. Kalinina
Publikováno v:
Retrovirology, Vol 17, Iss 1, Pp 1-14 (2020)
Abstract Background HIV-1 can develop resistance to antiretroviral drugs, mainly through mutations within the target regions of the drugs. In HIV-1 protease, a majority of resistance-associated mutations that develop in response to therapy with prote
Externí odkaz:
https://doaj.org/article/7e14234516e447aa8834a2af7952a526
Publikováno v:
F1000Research, Vol 9 (2020)
Cytoscape is an open-source software used to analyze and visualize biological networks. In addition to being able to import networks from a variety of sources, Cytoscape allows users to import tabular node data and visualize it onto networks. Unfortu
Externí odkaz:
https://doaj.org/article/4edaef55cd0e4fa79d05f9fe022e9533
Publikováno v:
F1000Research, Vol 9 (2020)
Cytoscape is an open-source software used to analyze and visualize biological networks. In addition to being able to import networks from a variety of sources, Cytoscape allows users to import tabular node data and visualize it onto networks. Unfortu
Externí odkaz:
https://doaj.org/article/75ba6d1745e04862873fb8f775b6bd9c