Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Nadezhda I, Fedotcheva"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1272 (2024)
Background: Research has shown the multiple actions of curcumin on different cell systems, including enzymes and mitochondria. The detected effects of curcumin on mitochondria are diverse, ranging from protective to toxic. Objectives: In this present
Externí odkaz:
https://doaj.org/article/e5136268d86243ac9170b6a60102859d
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1299 (2022)
The specific regulation of inflammatory processes by steroid hormones has been actively studied in recent years, especially by progesterone (P4) and progestins. The mechanisms of the anti-inflammatory and immunomodulatory P4 action are not fully clea
Externí odkaz:
https://doaj.org/article/e904594f643d4cdfb0c082111eac6e04
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2089 (2021)
Agrimoniin is a polyphenol from the group of tannins with antioxidant and anticancer activities. It is assumed that the anticancer action of agrimoniin is associated with the activation of mitochondria-dependent apoptosis, but its mitochondrial targe
Externí odkaz:
https://doaj.org/article/a9b00fe6505e4ddc95e7f5641345b75a
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1616 (2021)
Progesterone and its synthetic analogues, progestins, participate in the regulation of cell differentiation, proliferation and cell cycle progression. Progestins are usually applied for contraception, maintenance of pregnancy, and hormone replacement
Externí odkaz:
https://doaj.org/article/2810353826c5460080a931c4894b709a
Publikováno v:
Current Cancer Drug Targets. 21:514-525
Aim: The study is aimed at examining of action of iron, DOX, and their complex on the Mitochondrial Permeability Transition Pore (MPTP) opening and detecting of possible protectors of MPTP in the conditions close to mitochondria-dependent ferroptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5edebfef17aaa97eb49fc29d0a527212
https://doi.org/10.2174/1568009621999210120192558
https://doi.org/10.2174/1568009621999210120192558
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 15:82-88
This study was focused on the mechanisms of the protective effects of L-arginine and the nitric oxide donor SNAP under the induction of cyclosporine A-dependent mitochondrial permeability transition pore (MPTP) by excess of Ca2+ or D,L-palmitoylcarni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d55d47f230df81b9268551b2f1a4f97
https://doi.org/10.1134/s1990747820050050
https://doi.org/10.1134/s1990747820050050
Autor:
Nadezhda I. Fedotcheva, Eduard E. Varpetyan, Anna A. Kirsanova, N. L. Shimanovskii, Mikhail N. Sokolov, Konstantin V. Kudryavtsev, T. A. Fedotcheva
Publikováno v:
ChemistrySelect. 5:11467-11470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bd8b3bd37a202011e173360923c8aa2
https://doi.org/10.1002/slct.202003345
https://doi.org/10.1002/slct.202003345
Autor:
N. I. Sheina, Nadezhda I. Fedotcheva, T. A. Fedotcheva, E. D. Sveshnikova, Mikhail N. Sokolov, Konstantin V. Kudryavtsev, N. L. Shimanovskii
Publikováno v:
Pharmaceutical Chemistry Journal. 54:119-125
New mepregenol 17-acetate derivatives with potential cytotoxicity were synthesized. Mepregenol 17-acetate 3-acrylate (III) was shown to exhibit potent cytotoxicity although the ester of N-benzylpyrrolidine-3-carboxylic acid (IV) had weaker activity t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f311518cdc77ef4cf6ea9942e7ac4c1
https://doi.org/10.1007/s11094-020-02167-1
https://doi.org/10.1007/s11094-020-02167-1
Autor:
V. I. Sheichenko, Nadezhda I. Fedotcheva, N. L. Shimanovskii, O. P. Sheichenko, T. A. Fedotcheva
Publikováno v:
Pharmaceutical Chemistry Journal. 53:57-64
Escin-containing horse chestnut extracts and various medicinal formulations are widely used as venotonic agents whose mechanisms of action and intracellular targets remain unknown. Escin is used as an active substance to increase membrane permeabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1b2bca746778766a6aabd7b4b8d5be8
https://doi.org/10.1007/s11094-019-01956-7
https://doi.org/10.1007/s11094-019-01956-7
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 13:130-137
Mitochondrial dysfunction is the main factor in the development of multiple organ failure in sepsis. The role of microbial metabolites in the induction of mitochondrial dysfunction was studied in this work. The effect of phenolic acids of microbial o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b93c548082743ec709b329c624bf75d
https://doi.org/10.1134/s199074781806003x
https://doi.org/10.1134/s199074781806003x