Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Nadereh Jafari"'
Autor:
Juan Jose Carmona, Richard T. Barfield, Tommaso Panni, Jamaji C. Nwanaji-Enwerem, Allan C. Just, John N. Hutchinson, Elena Colicino, Stefan Karrasch, Simone Wahl, Sonja Kunze, Nadereh Jafari, Yinan Zheng, Lifang Hou, Dawn L. DeMeo, Augusto A. Litonjua, Pantel S. Vokonas, Annette Peters, Xihong Lin, Joel Schwartz, Holger Schulz, Andrea A. Baccarelli
Publikováno v:
Epigenetics, Vol 13, Iss 10-11, Pp 1039-1055 (2018)
DNA methylation is an epigenetic regulator of gene transcription, which has been found to be both metastable and variable within human cohort studies. Currently, few studies have been done to identify metastable DNA methylation biomarkers associated
Externí odkaz:
https://doaj.org/article/5d9982f725de4eee995fef75e29b36f8
Autor:
Yinan Zheng, Brian T. Joyce, Elena Colicino, Lei Liu, Wei Zhang, Qi Dai, Martha J. Shrubsole, Warren A. Kibbe, Tao Gao, Zhou Zhang, Nadereh Jafari, Pantel Vokonas, Joel Schwartz, Andrea A. Baccarelli, Lifang Hou
Publikováno v:
EBioMedicine, Vol 5, Iss C, Pp 68-73 (2016)
Biological measures of aging are important for understanding the health of an aging population, with epigenetics particularly promising. Previous studies found that tumor tissue is epigenetically older than its donors are chronologically. We examined
Externí odkaz:
https://doaj.org/article/168bef50f6ac4589811ad1b82e6dae04
Autor:
Diana Saleiro, Swarna Mehrotra, Barbara Kroczynska, Elspeth M. Beauchamp, Pawel Lisowski, Beata Majchrzak-Kita, Tushar D. Bhagat, Brady L. Stein, Brandon McMahon, Jessica K. Altman, Ewa M. Kosciuczuk, Darren P. Baker, Chunfa Jie, Nadereh Jafari, Craig B. Thompson, Ross L. Levine, Eleanor N. Fish, Amit K. Verma, Leonidas C. Platanias
Publikováno v:
Cell Reports, Vol 11, Iss 4, Pp 605-617 (2015)
We provide evidence that the Unc-51-like kinase 1 (ULK1) is activated during engagement of the type I interferon (IFN) receptor (IFNR). Our studies demonstrate that the function of ULK1 is required for gene transcription mediated via IFN-stimulated r
Externí odkaz:
https://doaj.org/article/634475be033c4f94ad88728b9a41870d
Autor:
Matthew T Dyson, Damian Roqueiro, Diana Monsivais, C Mutlu Ercan, Mary Ellen Pavone, David C Brooks, Toshiyuki Kakinuma, Masanori Ono, Nadereh Jafari, Yang Dai, Serdar E Bulun
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004158 (2014)
Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit spontaneous decidualization, and diseased cells are charact
Externí odkaz:
https://doaj.org/article/729a006ae3d94b1b8d8d9201cb320818
Autor:
Joao Trindade Marques, Ji-Ping Wang, Xiaohong Wang, Karla Pollyanna Vieira de Oliveira, Catherine Gao, Eric Roberto Guimaraes Rocha Aguiar, Nadereh Jafari, Richard W. Carthew
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/229d0339a81d438ba178203a9f7d2b1b
Autor:
Joao Trindade Marques, Ji-Ping Wang, Xiaohong Wang, Karla Pollyanna Vieira de Oliveira, Catherine Gao, Eric Roberto Guimaraes Rocha Aguiar, Nadereh Jafari, Richard W Carthew
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003579 (2013)
In Drosophila, post-transcriptional gene silencing occurs when exogenous or endogenous double stranded RNA (dsRNA) is processed into small interfering RNAs (siRNAs) by Dicer-2 (Dcr-2) in association with a dsRNA-binding protein (dsRBP) cofactor calle
Externí odkaz:
https://doaj.org/article/02dcde7e098749f5a519e21fab07a8d4
Autor:
Margrit Urbanek, M Geoffrey Hayes, Hoon Lee, Rachel M Freathy, Lynn P Lowe, Christine Ackerman, Nadereh Jafari, Alan R Dyer, Nancy J Cox, David B Dunger, Andrew T Hattersley, Boyd E Metzger, William L Lowe
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32958 (2012)
Since mediators of inflammation are associated with insulin resistance, and the risk of developing diabetes mellitus and gestational diabetes, we hypothesized that genetic variation in members of the inflammatory gene pathway impact glucose levels an
Externí odkaz:
https://doaj.org/article/312ea9c9afbd45fe926fb61a24a6f4fc
Autor:
Huixiao Hong, Lei Xu, Jie Liu, Wendell D Jones, Zhenqiang Su, Baitang Ning, Roger Perkins, Weigong Ge, Kelci Miclaus, Li Zhang, Kyunghee Park, Bridgett Green, Tao Han, Hong Fang, Christophe G Lambert, Silvia C Vega, Simon M Lin, Nadereh Jafari, Wendy Czika, Russell D Wolfinger, Federico Goodsaid, Weida Tong, Leming Shi
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44483 (2012)
During the last several years, high-density genotyping SNP arrays have facilitated genome-wide association studies (GWAS) that successfully identified common genetic variants associated with a variety of phenotypes. However, each of the identified ge
Externí odkaz:
https://doaj.org/article/f7b0abb5339e435fa63dd591f9847118
Autor:
Timothy B Lautz, Chunfa Jie, Sandra Clark, Jessica A Naiditch, Nadereh Jafari, Yi-Yong Qiu, Xin Zheng, Fei Chu, Mary Beth Madonna
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40816 (2012)
Histone deacetylase (HDAC) inhibitors, especially vorinostat, are currently under investigation as potential adjuncts in the treatment of neuroblastoma. The effect of vorinostat co-treatment on the development of resistance to other chemotherapeutic
Externí odkaz:
https://doaj.org/article/17a58affe10d4a95adc419d43b3cca6a
Autor:
Chiang-Ching Huang, Kiang Liu, Richard M Pope, Pan Du, Simon Lin, Nalini M Rajamannan, Qi-Quan Huang, Nadereh Jafari, Gregory L Burke, Wendy Post, Karol E Watson, Craig Johnson, Martha L Daviglus, Donald M Lloyd-Jones
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21067 (2011)
Atherosclerosis is the leading cause of cardiovascular disease (CVD). Traditional risk factors can be used to identify individuals at high risk for developing CVD and are generally associated with the extent of atherosclerosis; however, substantial n
Externí odkaz:
https://doaj.org/article/464cb70a249244c5918f2732486d493d