Zobrazeno 1 - 10
of 1 813
pro vyhledávání: '"Nader G"'
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundAnti-PD1 antibodies have gained popularity in the treatment of skin cancers. These drugs have been FDA approved for treatment of cutaneous melanoma and unresectable/metastatic squamous cell carcinoma of the skin. However, the use of anti-PD
Externí odkaz:
https://doaj.org/article/528f1b031da34f1fa9ef836afd616e0f
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundMetabolic syndrome (MetS) is an independent risk factor for chronic kidney disease (CKD) through many mechanisms, including activation of the renin–angiotensin system. The deleterious effects of angiotensin II (Ang II) can be counterbalan
Externí odkaz:
https://doaj.org/article/57174f65a26f49b891f5a78995a4ea25
Autor:
Rebecca D. Pratt, Cameron Brickman, Athar Nawab, Cameron Cottrill, Brian Snoad, Hari Vishal Lakhani, Austin Jelcick, Brandon Henderson, Niharika N. Bhardwaj, Juan R. Sanabria, Jiang Liu, Zijian Xie, Nader G. Abraham, Joseph I. Shapiro, Komal Sodhi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/69ae86fbd4c34e6b848bd31fb4ebba53
Autor:
Komal Sodhi, Krithika Srikanthan, Perrine Goguet-Rubio, Alexandra Nichols, Amrita Mallick, Athar Nawab, Rebecca Martin, Preeya T. Shah, Muhammad Chaudhry, Saroj Sigdel, Mehiar El-Hamdani, Jiang Liu, Zijian Xie, Nader G. Abraham, Joseph I. Shapiro
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f3a83a5b31c849e4a7d771ea01fea48e
Autor:
Salvatore Santo Signorelli, Luca Vanella, Nader G. Abraham, Salvatore Scuto, Elisa Marino, Petra Rocic
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 11 (2020)
Peripheral arterial disease (PAD) affects individuals particularly over 65 years old in the more advanced countries. Hemodynamic, inflammatory, and oxidative mechanisms interact in the pathophysiological scenario of this chronic arterial disease. We
Externí odkaz:
https://doaj.org/article/d6eeda0d20ed4094903f57b1cf343654
Autor:
Maayan Waldman, Keren Cohen, Dor Yadin, Vadim Nudelman, Dan Gorfil, Michal Laniado-Schwartzman, Ran Kornwoski, Dan Aravot, Nader G. Abraham, Michael Arad, Edith Hochhauser
Publikováno v:
Cardiovascular Diabetology, Vol 17, Iss 1, Pp 1-12 (2018)
Abstract Background Metabolic disorders such as obesity, insulin resistance and type 2 diabetes mellitus (DM2) are all linked to diabetic cardiomyopathy that lead to heart failure. Cardiomyopathy is initially characterized by cardiomyocyte hypertroph
Externí odkaz:
https://doaj.org/article/c10b07663a4e4317bbd204004a5c0238
Autor:
Zeid Khitan, Anna P. Shapiro, Preeya T. Shah, Juan R. Sanabria, Prasanna Santhanam, Komal Sodhi, Nader G. Abraham, Joseph I. Shapiro
Publikováno v:
Marshall Journal of Medicine, Vol 3, Iss 4, Pp 68-80 (2017)
Background: Understanding factors which predict progression of renal failure is of great interest to clinicians. Objectives: We examined machine learning methods to predict the composite outcome of death, dialysis or doubling of serum creatinine u
Externí odkaz:
https://doaj.org/article/b63c84bccd664aadb68b34b8bfda4d92
Autor:
Komal Sodhi, Krithika Srikanthan, Perrine Goguet-Rubio, Alexandra Nichols, Amrita Mallick, Athar Nawab, Rebecca Martin, Preeya T. Shah, Muhammad Chaudhry, Saroj Sigdel, Mehiar El-Hamdani, Jiang Liu, Zijian Xie, Nader G. Abraham, Joseph I. Shapiro
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract We have previously reported that the α1 subunit of sodium potassium adenosine triphosphatase (Na/K-ATPase), acts as a receptor and an amplifier for reactive oxygen species, in addition to its distinct pumping function. On this background, w
Externí odkaz:
https://doaj.org/article/37deb63da1474626b04b09bb0d90ef59
Autor:
David E. Stec, Nader G. Abraham
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 854 (2021)
This Special Issue collates and updates the current knowledge of the pharmacology and clinical applications concerning the enzyme heme oxygenase (HO) [...]
Externí odkaz:
https://doaj.org/article/c3dd6359956042b18b0fb8629d734acf
Autor:
Zi-jian Xie, Joel Novograd, Yaakov Itzkowitz, Ariel Sher, Yosef D. Buchen, Komal Sodhi, Nader G. Abraham, Joseph I. Shapiro
Publikováno v:
Antioxidants, Vol 9, Iss 11, p 1129 (2020)
This review summarizes data from several laboratories that have demonstrated a role of the Na/K-ATPase, specifically its α1 subunit, in the generation of reactive oxygen species (ROS) via the negative regulator of Src. Together with Src and other si
Externí odkaz:
https://doaj.org/article/0c0cf6d1c53f4134bf93da0d0ee29b6d