Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nader D. Halim"'
Autor:
Nader D. Halim, John Doyle
Publikováno v:
Therapeutic Innovation & Regulatory Science. 47:306-311
Taking treatments from bench to bedside, or bench to community, requires a viable pathway connecting molecular science to global need through public and private research funding, clinical development, drug marketing, and policy making. In this paper,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1fa65178e83adc52cfc4452c775e755
https://doi.org/10.1177/2168479013482315
https://doi.org/10.1177/2168479013482315
Autor:
Robert A. Harris, Nader D. Halim, Peter Okagaki, Michael J. Schell, Lioubov G. Korotchkina, Ajay Verma, Thomas McFate, Mulchand S. Patel, Nam Ho Jeoung, Ahmed Mohyeldin
Publikováno v:
Glia. 58:1168-1176
Glucose metabolism in nervous tissue has been proposed to occur in a compartmentalized manner with astrocytes contributing largely to glycolysis and neurons being the primary site of glucose oxidation. However, mammalian astrocytes and neurons both c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1239c149167e0969036fca9c541178c3
https://doi.org/10.1002/glia.20996
https://doi.org/10.1002/glia.20996
Autor:
Mitsuyuki Matsumoto, Thomas M. Hyde, Jose A. Apud, Samer Melhem, Barbara K. Lipska, Quang D. Ma, Jingshan Chen, Mary M. Herman, Daniel R. Weinberger, Bhaskar Kolachana, Joel E. Kleinman, Nader D. Halim, Michael F. Egan
Publikováno v:
The American Journal of Human Genetics. 75:807-821
Catechol-O-methyltransferase (COMT) is a key enzyme in the elimination of dopamine in the prefrontal cortex of the human brain. Genetic variation in the COMT gene (MIM 116790) has been associated with altered prefrontal cortex function and higher ris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b284e366d77082093e7c5b1c9410ef71
https://doi.org/10.1086/425589
https://doi.org/10.1086/425589
Autor:
Benjamin W. McClintock, Daniel R. Weinberger, Cynthia Shannon Weickert, Nader D. Halim, Barbara K. Lipska
Publikováno v:
Neuropsychopharmacology. 29:1063-1069
It has been proposed that the therapeutic benefits of treatment with antidepressants and mood stabilizers may arise partially from their ability to stimulate neurogenesis. This study was designed to examine the effects of chronic antipsychotic treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c77e0317e30e9f33121012cae4d1ab
https://doi.org/10.1038/sj.npp.1300422
https://doi.org/10.1038/sj.npp.1300422
Publikováno v:
Behavioural Brain Research. 141:105-111
We examined in the rat, the effects of neonatal (postnatal Day 7) and adult excitotoxic lesions of the mediodorsal thalamus (MDT), a brain area innervating the prefrontal cortex and implicated as a site of neuropathology in schizophrenia. Previous st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c44744bcc4d9b695b3067400498b7a5
https://doi.org/10.1016/s0166-4328(03)00027-5
https://doi.org/10.1016/s0166-4328(03)00027-5
Publikováno v:
Brain Research. 898:195-203
Prepulse inhibition (PPI) of the startle reflex is a measure of sensorimotor gating that is reduced in humans with certain neuropsychiatric disorders, including schizophrenia, and in rats after manipulations of limbic cortico-striato-pallido-pontine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7097b82ee754d6b6d26a3ad636930de0
https://doi.org/10.1016/s0006-8993(01)02143-6
https://doi.org/10.1016/s0006-8993(01)02143-6
Autor:
Nader D Halim, Neal R. Swerdlow
Publikováno v:
Brain Research. 873:60-74
An enhanced sensitivity to the behavioral effects of dopamine (DA) agonists in adult rats occurs after cytotoxic lesions of the ventral hippocampus (vHPC). While some of these behavioral changes may model specific abnormalities in schizophrenia patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849d0494bd8a68d4bf1c02916a8691a4
https://doi.org/10.1016/s0006-8993(00)02497-5
https://doi.org/10.1016/s0006-8993(00)02497-5
Publikováno v:
Pharmacology Biochemistry and Behavior. 65:449-457
NMDA antagonists and dopamine (DA) agonists produce neuropathological and/or behavioral changes in rats that may model specific abnormalities in schizophrenia patients. In adult rats, NMDA antagonists and DA agonists disrupt sensorimotor gating-measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686f1124e3be24228fafa01da292484f
https://doi.org/10.1016/s0091-3057(99)00217-8
https://doi.org/10.1016/s0091-3057(99)00217-8
Publikováno v:
Neuroscience. 96:523-536
Prepulse inhibition of the startle reflex is an operational measure of sensorimotor gating that is impaired in schizophrenia patients and dopamine agonist-treated rats. Previous reports demonstrated an enhanced sensitivity to the prepulse inhibition-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0315bc9416880c80dc0d4ffe2be67b
https://doi.org/10.1016/s0306-4522(99)00528-x
https://doi.org/10.1016/s0306-4522(99)00528-x
Autor:
Nader D, Halim, Thomas, Mcfate, Ahmed, Mohyeldin, Peter, Okagaki, Lioubov G, Korotchkina, Mulchand S, Patel, Nam Ho, Jeoung, Robert A, Harris, Michael J, Schell, Ajay, Verma
Publikováno v:
Glia. 58(10)
Glucose metabolism in nervous tissue has been proposed to occur in a compartmentalized manner with astrocytes contributing largely to glycolysis and neurons being the primary site of glucose oxidation. However, mammalian astrocytes and neurons both c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fabeab2ab656d65e4ae560f8415b08c
https://pubmed.ncbi.nlm.nih.gov/20544852
https://pubmed.ncbi.nlm.nih.gov/20544852