Výsledky vyhledávání - "Nader, Zahedi Golpayegani"

Oxadiazole-substituted naphtho[2,3- b ]thiophene-4,9-diones as potent inhibitors of keratinocyte hyperproliferation. Structure−activity relationships of the tricyclic quinone skeleton and the oxadiazole substituent

Autor: Dominica Nowottnik, Atila Basoglu, Silke Vortherms, Roland Fröhlich, Helge Prinz, Klaus Müller, Simone Dirkmann, Jan Tentrop, Nader Zahedi Golpayegani

Publikováno v: European Journal of Medicinal Chemistry. 134:119-132

Novel analogues of oxadiazole-substituted naphtho[2,3-b]thiophene-4,9-diones were synthesized in which the tricyclic quinone skeleton was systematically replaced with simpler moieties, such as structures with fewer rings and open-chain forms, while t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e40301ceb4fddf012aa5623e417119a
https://doi.org/10.1016/j.ejmech.2017.03.084

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Synthesis and Structure–Activity Relationships of Lapacho Analogues. 2. Modification of the Basic Naphtho[2,3-b]furan-4,9-dione, Redox Activation, and Suppression of Human Keratinocyte Hyperproliferation by 8-Hydroxynaphtho[2,3-b]thiophene-4,9-diones

Autor: Cathrin Lindenschmidt, Helge Prinz, Sven Bannwitz, Tobias Kalin, Klaus Müller, Jan Tentrop, Silke Vortherms, Nader Zahedi Golpayegani, Dirk Krane

Publikováno v: Journal of Medicinal Chemistry. 57:6226-6239

The basic structure of linearly anellated lapacho quinones, naphtho[2,3-b]furan-4,9-dione (7), was modified in the search for novel agents against keratinocyte hyperproliferation. The synthesis and structure–activity relationships of several hetero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14765c3265ad33042f9bd01e462d2179
https://doi.org/10.1021/jm500754d

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Synthesis and structure-activity relationships of lapacho analogues. 2. Modification of the basic naphtho[2,3-b]furan-4,9-dione, redox activation, and suppression of human keratinocyte hyperproliferation by 8-hydroxynaphtho[2,3-b]thiophene-4,9-diones

Autor: Sven, Bannwitz, Dirk, Krane, Silke, Vortherms, Tobias, Kalin, Cathrin, Lindenschmidt, Nader, Zahedi Golpayegani, Jan, Tentrop, Helge, Prinz, Klaus, Müller

Publikováno v: Journal of medicinal chemistry. 57(14)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::39e7a404a202433fd088612cc14b0034
https://pubmed.ncbi.nlm.nih.gov/24964246

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