Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nadejda Lopatina"'
Autor:
Lucy G. Andrews, Mark A Pita, Nathaniel J. Hansen, Sabita N. Saldanha, Jason S Key, Joseph C Poole, Nadejda Lopatina, Trygve O. Tollefsbol
Publikováno v:
Biochemical and Biophysical Research Communications. 306:650-659
Telomerase is active in about 90% of cancers and contributes to the immortality of cancer cells by maintaining the lengths of the ends of chromosomes. Undifferentiated embryonic human teratocarcinoma (HT) cells were found to express high levels of hT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864a021d0daf24d30e023a46cd0e0e18
https://doi.org/10.1016/s0006-291x(03)01033-7
https://doi.org/10.1016/s0006-291x(03)01033-7
Autor:
Trygve O. Tollefsbol, Sabita N. Saldanha, Lucy G. Andrews, Joyce F. Haskell, Joseph C Poole, Nadejda Lopatina
Publikováno v:
Journal of Cellular Biochemistry. 84:324-334
Genomic methylation, which influences many cellular processes such as gene expression and chromatin organization, generally declines with cellular senescence although some genes undergo paradoxical hypermethylation during cellular aging and immortali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad32cee6d2db12789f1b40f1e2d4689
https://doi.org/10.1002/jcb.10015
https://doi.org/10.1002/jcb.10015
Publikováno v:
Molecular and cellular biochemistry. 252(1-2)
Although it has been known for quite some time that genomic methylation is significantly altered in aging and neoplastic tissues and cells, the underlying mechanisms responsible for these alterations are not yet known. Since DNA methylation affects m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fc33f871e4289289066333743881f68
https://pubmed.ncbi.nlm.nih.gov/14577574
https://pubmed.ncbi.nlm.nih.gov/14577574