Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Nadejda, Sigal"'
Autor:
Moran Brenner, Sivan Friedman, Adi Haber, Nurit Livnat-Levanon, Ilya Borovok, Nadejda Sigal, Oded Lewinson, Anat A. Herskovits
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Listeria monocytogenes is a saprophyte and a human intracellular pathogen. Upon invasion into mammalian cells, it senses multiple metabolic and environmental signals that collectively trigger its transition to the pathogenic state. One of th
Externí odkaz:
https://doaj.org/article/0fa22f51cb364dc68255151b8b560907
Autor:
Tal Argov, Shai Ran Sapir, Anna Pasechnek, Gil Azulay, Olga Stadnyuk, Lev Rabinovich, Nadejda Sigal, Ilya Borovok, Anat A. Herskovits
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Bacterial pathogens often carry multiple phage-derived elements within their genome. Here, the authors show that two phage elements are co-regulated in Listeria monocytogenes, the first one controlling the induction of the second one, which in turn r
Externí odkaz:
https://doaj.org/article/90351ba3242b490ea07d73b8b9a04d61
Autor:
Anna Pasechnek, Lev Rabinovich, Olga Stadnyuk, Gil Azulay, Jessica Mioduser, Tal Argov, Ilya Borovok, Nadejda Sigal, Anat A. Herskovits
Publikováno v:
Cell Reports, Vol 32, Iss 4, Pp 107956- (2020)
Summary: Some Listeria monocytogenes (Lm) strains harbor a prophage within the comK gene, which renders it inactive. During Lm infection of macrophage cells, the prophage turns into a molecular switch, promoting comK gene expression and therefore Lm
Externí odkaz:
https://doaj.org/article/a0e96ccc0c0c41a8a648c012d4ad2073
Publikováno v:
Microorganisms, Vol 9, Iss 6, p 1323 (2021)
Infection of mammalian cells by Listeria monocytogenes (Lm) was shown to be facilitated by its phage elements. In a search for additional phage remnants that play a role in Lm’s lifecycle, we identified a conserved locus containing two XRE regulato
Externí odkaz:
https://doaj.org/article/96343b87875b48dcb879bfa0be6141f6
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007283 (2018)
Listeria monocytogenes (Lm) is a saprophyte and intracellular pathogen. Transition to the pathogenic state relies on sensing of host-derived metabolites, yet it remains unclear how these are recognized and how they mediate virulence gene regulation.
Externí odkaz:
https://doaj.org/article/ca273cf3755243a59e38422052e6d75d
Autor:
Adi Haber, Sivan Friedman, Lior Lobel, Tamar Burg-Golani, Nadejda Sigal, Jessica Rose, Nurit Livnat-Levanon, Oded Lewinson, Anat A Herskovits
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006161 (2017)
The high environmental adaptability of bacteria is contingent upon their ability to sense changes in their surroundings. Bacterial pathogen entry into host poses an abrupt and dramatic environmental change, during which successful pathogens gauge mul
Externí odkaz:
https://doaj.org/article/9520c67bc0ce429cb15117587b7ada60
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-9 (2010)
Abstract Gene expression varies widely between closely related species and strains, yet the genetic basis of most differences is still unknown. Several studies suggested that chromatin regulators have a key role in generating expression diversity, pr
Externí odkaz:
https://doaj.org/article/c021fdebcfd14c8088b2ba972f0d4c8e
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-10 (2010)
Abstract Gene regulation differs greatly between related species, constituting a major source of phenotypic diversity. Recent studies characterized extensive differences in the gene expression programs of closely related species. In contrast, virtual
Externí odkaz:
https://doaj.org/article/156705b3f86144b784f9fbc9305f29f6
Publikováno v:
Bio-Protocol, Vol 5, Iss 22 (2015)
Studying the transcriptome of bacterial pathogens during infection is a very informative and effective tool for discovering genes that contribute to successful infection. However, isolating bacterial RNA from infected cells or tissues is a challengin
Externí odkaz:
https://doaj.org/article/f048672dadf84ea48ffbb96a43e5e54b
Publikováno v:
Microorganisms
Volume 9
Issue 6
Microorganisms, Vol 9, Iss 1323, p 1323 (2021)
Volume 9
Issue 6
Microorganisms, Vol 9, Iss 1323, p 1323 (2021)
Infection of mammalian cells by Listeria monocytogenes (Lm) was shown to be facilitated by its phage elements. In a search for additional phage remnants that play a role in Lm’s lifecycle, we identified a conserved locus containing two XRE regulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95c761935f83e84658391c572a98564
https://pubmed.ncbi.nlm.nih.gov/34207021
https://pubmed.ncbi.nlm.nih.gov/34207021