Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Nadeem Wajih"'
Autor:
Steven D. Forsythe, Richard A. Erali, Nicholas Edenhoffer, William Meeker, Nadeem Wajih, Cecilia R. Schaaf, Preston Laney, Cristian D. Vanezuela, Wencheng Li, Edward A. Levine, Shay Soker, Konstantinos I. Votanopoulos
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Peritoneal mesothelioma (PM) is a rare malignancy with poor prognosis, representing about 10–15% of all mesothelioma cases. Herein we apply PM patient-derived tumor organoids (PTOs) in elucidating personalized HIPEC responses to bypass rar
Externí odkaz:
https://doaj.org/article/b06ce63a27604f8892e9538a0600cbd8
Autor:
Nadeem Wajih, Swati Basu, Kamil B. Ucer, Fernando Rigal, Aryatara Shakya, Elaheh Rahbar, Vidula Vachharajani, Martin Guthold, Mark T. Gladwin, Lane M. Smith, Daniel B. Kim-Shapiro
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 442-450 (2019)
Background: Nitrite is reduced by heme-proteins and molybdenum-containing enzymes to form the important signaling molecule nitric oxide (NO), mediating NO signaling. Substantial evidence suggests that deoxygenated hemoglobin within red blood cells (R
Externí odkaz:
https://doaj.org/article/72b40045b28e4e4988bf3051e3111c48
Autor:
Nadeem Wajih, Swati Basu, Anuj Jailwala, Hee Won Kim, David Ostrowski, Andreas Perlegas, Crystal A. Bolden, Nancy L. Buechler, Mark T. Gladwin, David L. Caudell, Elaheh Rahbar, Martha A. Alexander-Miller, Vidula Vachharajani, Daniel B. Kim-Shapiro
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 1026-1039 (2017)
Sickle cell disease is caused by a mutant form of hemoglobin that polymerizes under hypoxic conditions, increasing rigidity, fragility, calcium influx-mediated dehydration, and adhesivity of red blood cells. Increased red cell fragility results in he
Externí odkaz:
https://doaj.org/article/6cbd35867bd04e4cafdee1f7691998b9
Autor:
Nadeem Wajih, Xiaohua Liu, Pragna Shetty, Swati Basu, Hanzhi Wu, Neil Hogg, Rakesh P. Patel, Cristina M. Furdui, Daniel B. Kim-Shapiro
Publikováno v:
Redox Biology, Vol 8, Iss C, Pp 415-421 (2016)
Previous work has shown that red blood cells (RBCs) reduce nitrite to NO under conditions of low oxygen. Strong support for the ability of red blood cells to promote nitrite bioactivation comes from using platelet activation as a NO-sensitive process
Externí odkaz:
https://doaj.org/article/78233787878647679ffcca1430b55d88
Publikováno v:
Cancer Research. 83:P3-09
Introduction: Breast cancer is one of the most frequently diagnosed cancer in women with a high mortality rate. More than 20 different subtypes of breast cancer are identified. Advancement in patient-derived organoid technology makes it possible to p
Autor:
Richard A. Erali, Steven D. Forsythe, Daniel J. Gironda, Cecilia R. Schaaf, Nadeem Wajih, Shay Soker, Konstantinos I. Votanopoulos
Publikováno v:
Journal of Gastrointestinal Cancer.
Autor:
Steven D. Forsythe, Hemamylammal Sivakumar, Richard A. Erali, Nadeem Wajih, Wencheng Li, Perry Shen, Edward A. Levine, Katherine E. Miller, Aleksander Skardal, Konstantinos I. Votanopoulos
Publikováno v:
Annals of surgical oncology. 29(12)
Autor:
Steven Donald Forsythe, Richard A. Erali, Preston Laney, William Meeker, Salomat Abdulkhuseynova, Nadeem Wajih, Nicholas Edenhoffer, Cecilia R. Schaaf, Hemamyammal Sivakumar, Aleksander Skardal, Roy E. Strowd, Stephen B. Tatter, Clancy J. Clark, Reese W. Randle, Perry Shen, Edward A. Levine, Ralph B. D'Agostino, Shay Soker, Konstantinos I. Votanopoulos
Publikováno v:
Cancer Research. 83:150-150
Introduction: Patient tumor organoids (PTOs) are a new and developing preclinical model in cancer research. However, there is variation in protocols between centers and lack of consistency in important variables, impacting PTO culture success. In thi
Publikováno v:
Cancer Research. 83:164-164
Introduction: Breast cancer is one of the most frequently diagnosed cancers among women, with a high mortality rate. More than 20 different subtypes of breast cancer are identified. Advancement in patient-derived organoid technology makes it possible
Autor:
Jiqing Zhu, Nadeem Wajih, Daniel B. Kim-Shapiro, Andreas Perlegas, Elmira Alipour, Fernando Rigal, David L. Caudell
Publikováno v:
Nitric Oxide
Nitric oxide, NO, has been explored as a therapeutic agent to treat thrombosis. In particular, NO has potential in treating mechanical device-associated thrombosis due to its ability to reduce platelet activation and due to the central role of platel