Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Nadeem O, Kaakoush"'
Autor:
Marwan E. Majzoub, Sudarshan Paramsothy, Craig Haifer, Rohit Parthasarathy, Thomas J. Borody, Rupert W. Leong, Michael A. Kamm, Nadeem O. Kaakoush
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Bacteriophages are influential within the human gut microbiota, yet they remain understudied relative to bacteria. This is a limitation of studies on fecal microbiota transplantation (FMT) where bacteriophages likely influence outcome. Here,
Externí odkaz:
https://doaj.org/article/6312f0fcd8a2407289631b357b8753cf
Autor:
Marwan E. Majzoub, Laurence D. W. Luu, Craig Haifer, Sudarshan Paramsothy, Thomas J. Borody, Rupert W. Leong, Torsten Thomas, Nadeem O. Kaakoush
Publikováno v:
mSystems, Vol 9, Iss 9 (2024)
ABSTRACT Characterization of microbial community metabolic output is crucial to understanding their functions. Construction of genome-scale metabolic models from metagenome-assembled genomes (MAG) has enabled prediction of metabolite production by mi
Externí odkaz:
https://doaj.org/article/465af0d3cac84b1698b9440a8509eab0
Autor:
Laurence D. W. Luu, Abhimanu Pandey, Sudarshan Paramsothy, Chinh Ngo, Natalia Castaño-Rodríguez, Cheng Liu, Michael A. Kamm, Thomas J. Borody, Si Ming Man, Nadeem O. Kaakoush
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Host molecular responses to fecal microbiota transplantation (FMT) in ulcerative colitis are not well understood. Here, we profile the human colonic mucosal transcriptome prior to and following FMT or placebo to identify molecules regulated
Externí odkaz:
https://doaj.org/article/8fb4cb1f0049425d9de3a9f287ea6c0f
Publikováno v:
Nutrients, Vol 16, Iss 19, p 3233 (2024)
Background: Diet has been linked to gut dysbiosis and the onset, course, and response to treatment of patients with IBD and metabolic disease. Methods: This single-centre prospective case-control study investigated the relationship between dietary in
Externí odkaz:
https://doaj.org/article/4abffc08dc4242f1bef97d6926f87da8
Autor:
Kyoko Hasebe, Michael D. Kendig, Nadeem O. Kaakoush, Aynaz Tajaddini, R. Frederick Westbrook, Margaret J. Morris
Publikováno v:
Animal Microbiome, Vol 4, Iss 1, Pp 1-14 (2022)
Abstract Background Despite well-known effects of diet on gut microbiota diversity, relatively little is known about how maternal diet quality shapes the longitudinal maturation of gut microbiota in offspring. To investigate, we fed female rats stand
Externí odkaz:
https://doaj.org/article/f3af96bb5e364556b133a6770b33fdb6
Autor:
Valentina Rodriguez Paris, Xin Yi Denise Wong, Samantha M Solon-Biet, Melissa C Edwards, Ali Aflatounian, Robert B Gilchrist, Stephen J Simpson, David J Handelsman, Nadeem O Kaakoush, Kirsty A Walters
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The gut microbiome has been implicated in polycystic ovary syndrome (PCOS) pathophysiology. PCOS is a disorder with reproductive, endocrine and metabolic irregularities, and several studies report that PCOS is associated with a decrease in microbial
Externí odkaz:
https://doaj.org/article/b8726557763444eca5d070104fa8422e
Publikováno v:
Pathogens, Vol 12, Iss 9, p 1087 (2023)
Liver disease is a major global health problem leading to approximately two million deaths a year. This is the consequence of a number of aetiologies, including alcohol-related, metabolic-related, viral infection, cholestatic and immune disease, lead
Externí odkaz:
https://doaj.org/article/93775b3b503c411fad5de6b6bdd8392d
Autor:
Nandan P. Deshpande, Stephen M. Riordan, Claire J. Gorman, Shaun Nielsen, Tonia L. Russell, Carolina Correa-Ospina, Bentotage S. M. Fernando, Shafagh A. Waters, Natalia Castaño-Rodríguez, Si Ming Man, Nicodemus Tedla, Marc R. Wilkins, Nadeem O. Kaakoush
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-21 (2021)
Abstract Background The enrichment of Gram-negative bacteria of oral origin in the esophageal microbiome has been associated with the development of metaplasia. However, to date, no study has comprehensively assessed the relationships between the eso
Externí odkaz:
https://doaj.org/article/c61c2146d72f45c6ae5712c83199fd89
Autor:
Briana K. Clifford, Nadia M. L. Amorim, Nadeem O. Kaakoush, Lykke Boysen, Nicodemus Tedla, David Goldstein, Edna C. Hardeman, David Simar
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5631 (2023)
The negative impact of irradiation or diet on the metabolic and immune profiles of cancer survivors have been previously demonstrated. The gut microbiota plays a critical role in regulating these functions and is highly sensitive to cancer therapies.
Externí odkaz:
https://doaj.org/article/c14d8b8b51474df5a219f95da01d9016
Autor:
Sarah-Jane Leigh, Nadeem O. Kaakoush, Rosa M. Escorihuela, R. Frederick Westbrook, Margaret J. Morris
Publikováno v:
Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background Exercise has been extensively utilised as an effective therapy for overweight- and obesity-associated changes that are linked to health complications. Several preclinical rodent studies have shown that treadmill exercise alongside
Externí odkaz:
https://doaj.org/article/08a887deddc24ec1a4164d48795fe003