Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Nadeem O, Kaakoush"'
Autor:
Marwan E. Majzoub, Sudarshan Paramsothy, Craig Haifer, Rohit Parthasarathy, Thomas J. Borody, Rupert W. Leong, Michael A. Kamm, Nadeem O. Kaakoush
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Bacteriophages are influential within the human gut microbiota, yet they remain understudied relative to bacteria. This is a limitation of studies on fecal microbiota transplantation (FMT) where bacteriophages likely influence outcome. Here,
Externí odkaz:
https://doaj.org/article/6312f0fcd8a2407289631b357b8753cf
Autor:
Marwan E. Majzoub, Laurence D. W. Luu, Craig Haifer, Sudarshan Paramsothy, Thomas J. Borody, Rupert W. Leong, Torsten Thomas, Nadeem O. Kaakoush
Publikováno v:
mSystems, Vol 9, Iss 9 (2024)
ABSTRACT Characterization of microbial community metabolic output is crucial to understanding their functions. Construction of genome-scale metabolic models from metagenome-assembled genomes (MAG) has enabled prediction of metabolite production by mi
Externí odkaz:
https://doaj.org/article/465af0d3cac84b1698b9440a8509eab0
Autor:
Laurence D. W. Luu, Abhimanu Pandey, Sudarshan Paramsothy, Chinh Ngo, Natalia Castaño-Rodríguez, Cheng Liu, Michael A. Kamm, Thomas J. Borody, Si Ming Man, Nadeem O. Kaakoush
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Host molecular responses to fecal microbiota transplantation (FMT) in ulcerative colitis are not well understood. Here, we profile the human colonic mucosal transcriptome prior to and following FMT or placebo to identify molecules regulated
Externí odkaz:
https://doaj.org/article/8fb4cb1f0049425d9de3a9f287ea6c0f
Autor:
Kyoko Hasebe, Michael D. Kendig, Nadeem O. Kaakoush, Aynaz Tajaddini, R. Frederick Westbrook, Margaret J. Morris
Publikováno v:
Animal Microbiome, Vol 4, Iss 1, Pp 1-14 (2022)
Abstract Background Despite well-known effects of diet on gut microbiota diversity, relatively little is known about how maternal diet quality shapes the longitudinal maturation of gut microbiota in offspring. To investigate, we fed female rats stand
Externí odkaz:
https://doaj.org/article/f3af96bb5e364556b133a6770b33fdb6
Autor:
Valentina Rodriguez Paris, Xin Yi Denise Wong, Samantha M Solon-Biet, Melissa C Edwards, Ali Aflatounian, Robert B Gilchrist, Stephen J Simpson, David J Handelsman, Nadeem O Kaakoush, Kirsty A Walters
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The gut microbiome has been implicated in polycystic ovary syndrome (PCOS) pathophysiology. PCOS is a disorder with reproductive, endocrine and metabolic irregularities, and several studies report that PCOS is associated with a decrease in microbial
Externí odkaz:
https://doaj.org/article/b8726557763444eca5d070104fa8422e
Publikováno v:
Pathogens, Vol 12, Iss 9, p 1087 (2023)
Liver disease is a major global health problem leading to approximately two million deaths a year. This is the consequence of a number of aetiologies, including alcohol-related, metabolic-related, viral infection, cholestatic and immune disease, lead
Externí odkaz:
https://doaj.org/article/93775b3b503c411fad5de6b6bdd8392d
Autor:
Nandan P. Deshpande, Stephen M. Riordan, Claire J. Gorman, Shaun Nielsen, Tonia L. Russell, Carolina Correa-Ospina, Bentotage S. M. Fernando, Shafagh A. Waters, Natalia Castaño-Rodríguez, Si Ming Man, Nicodemus Tedla, Marc R. Wilkins, Nadeem O. Kaakoush
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-21 (2021)
Abstract Background The enrichment of Gram-negative bacteria of oral origin in the esophageal microbiome has been associated with the development of metaplasia. However, to date, no study has comprehensively assessed the relationships between the eso
Externí odkaz:
https://doaj.org/article/c61c2146d72f45c6ae5712c83199fd89
Autor:
Sarah-Jane Leigh, Nadeem O. Kaakoush, Rosa M. Escorihuela, R. Frederick Westbrook, Margaret J. Morris
Publikováno v:
Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background Exercise has been extensively utilised as an effective therapy for overweight- and obesity-associated changes that are linked to health complications. Several preclinical rodent studies have shown that treadmill exercise alongside
Externí odkaz:
https://doaj.org/article/08a887deddc24ec1a4164d48795fe003
Autor:
Daniel Fox, Anukriti Mathur, Yansong Xue, Yunqi Liu, Wei Hong Tan, Shouya Feng, Abhimanu Pandey, Chinh Ngo, Jenni A. Hayward, Ines I. Atmosukarto, Jason D. Price, Matthew D. Johnson, Nadja Jessberger, Avril A. B. Robertson, Gaetan Burgio, David C. Tscharke, Edward M. Fox, Denisse L. Leyton, Nadeem O. Kaakoush, Erwin Märtlbauer, Stephen H. Leppla, Si Ming Man
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The Bacillus haemolytic enterotoxin haemolysin BL has been shown to activate the NLRP3 inflammasome. Here the authors show that a non-haemolytic enterotoxin (NHE) from B. cereus can also activate the NLRP3 inflammasome with a similar mechanism of lyt
Externí odkaz:
https://doaj.org/article/a3d1c668fd514f4c9ccf1972f0c941e9
Autor:
Natalia Castaño-Rodríguez, Georgia L. Popple, Gloria Liliana Porras-Hurtado, José Luis Cardona-Deazza, Juan José Montoya-Martinez, Antonio Javier Cadavid-Velez, Héctor William Toro-Hidalgo, Alba Ruth Cobo-Alvarado, Ofelia del Socorro Hincapié-Rincón, Stephen M. Riordan, Nadeem O. Kaakoush
Publikováno v:
Biomarker Research, Vol 6, Iss 1, Pp 1-7 (2018)
Abstract OPCML hypermethylation is considered a promising cancer biomarker. We examined methylation levels in the first exon of OPCML in two patient cohorts within the esophageal adenocarcinoma and gastric adenocarcinoma cascades and in a range of ce
Externí odkaz:
https://doaj.org/article/450c677138a24efe9136cf49e6623f48