Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Nadeem, Moghal"'
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 5688-5702 (2023)
Abstract Background Lung squamous cell carcinoma (LUSC) currently has limited therapeutic options because of the relatively few validated targets and the lack of clinical drugs for some of these targets. Although NRF2/NFE2L2 pathway activation common
Externí odkaz:
https://doaj.org/article/43677a905b7b403981e1fc2c470aac97
Autor:
Shideh Mirhadi, Shirley Tam, Quan Li, Nadeem Moghal, Nhu-An Pham, Jiefei Tong, Brian J. Golbourn, Jonathan R. Krieger, Paul Taylor, Ming Li, Jessica Weiss, Sebastiao N. Martins-Filho, Vibha Raghavan, Yasin Mamatjan, Aafaque A. Khan, Michael Cabanero, Shingo Sakashita, Kugeng Huo, Sameer Agnihotri, Kota Ishizawa, Thomas K. Waddell, Gelareh Zadeh, Kazuhiro Yasufuku, Geoffrey Liu, Frances A. Shepherd, Michael F. Moran, Ming-Sound Tsao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
With non-small cell lung cancer (NSCLC) being the leading cause of cancer deaths worldwide, the development of targeted therapies remains crucial. Here, the generation and multi-omics characterization of 137 NSCLC patient-derived xenografts provides
Externí odkaz:
https://doaj.org/article/ca6f25a2b4ee419cb65ec4d91e659e4f
Autor:
Joshua C. Rosen, Jessica Weiss, Nhu-An Pham, Quan Li, Sebastiao N. Martins-Filho, Yuhui Wang, Ming-Sound Tsao, Nadeem Moghal
Publikováno v:
Translational Oncology, Vol 14, Iss 10, Pp 101179- (2021)
Gain-of-function Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations occur in 25% of lung adenocarcinomas, and these tumors are challenging to treat. Some preclinical work, largely based on cell lines, suggested KRASmut lung cancers are espec
Externí odkaz:
https://doaj.org/article/89a26fc9aa484300990da8508907c577
Autor:
Jing Hao, Cédric Zeltz, Melania Pintilie, Quan Li, Shingo Sakashita, Tao Wang, Michael Cabanero, Sebastiao N. Martins-Filho, Dennis Y. Wang, Elena Pasko, Kalpana Venkat, Joella Joseph, Vibha Raghavan, Chang-Qi Zhu, Yu-Hui Wang, Nadeem Moghal, Ming-Sound Tsao, Roya Navab
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 5, Pp 482-493 (2019)
Carcinoma-associated fibroblasts (CAFs) are abundant stromal cells in tumor microenvironment that are critically involved in cancer progression. Contrasting reports have shown that CAFs can have either pro- or antitumorigenic roles, indicating that C
Externí odkaz:
https://doaj.org/article/dee2915adb844c6bb8509c156a0669fc
Publikováno v:
Cancer Medicine. 12:5688-5702
Lung squamous cell carcinoma (LUSC) currently has limited therapeutic options because of the relatively few validated targets and the lack of clinical drugs for some of these targets. Although NRF2/NFE2L2 pathway activation commonly occurs in LUSC, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3dd9b7468f9ebeba81e906c78b38aea
https://doi.org/10.1002/cam4.5311
https://doi.org/10.1002/cam4.5311
Autor:
Ming Li, Quan Li, Ni Liu, Frances A. Shepherd, Teklab Gebregiworgis, Ming-Sound Tsao, Nadeem Moghal, Nhu-An Pham, Mitsuhiko Ikura, Ningdi Feng Liu, Zhenhao Fang, Hirotsugu Notsuda, Ku-Geng Huo, Christopher B. Marshall
Publikováno v:
Journal of Thoracic Oncology. 17:277-288
Introduction Mutations in BRAF occur in 2-4% of lung adenocarcinoma (LUAD) patients. Combination dabrafenib/trametinib or single-agent vemurafenib is approved only for patients with cancers driven by the V600E BRAF mutation. Targeted therapy is not c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01fccde292ddc9f80ca06196fd41dd14
https://doi.org/10.1016/j.jtho.2021.09.008
https://doi.org/10.1016/j.jtho.2021.09.008
Autor:
Ming-Sound Tsao, Nadeem Moghal, Geoffrey Liu, Benjamin Haibe-Kains, Nhu-An Pham, Laura Tamblyn, Yu-Hui Wang, Ming Li, Joshua C. Rosen, Arvind Singh Mer, Quan Li, Vibha Raghavan, Sebastiao N. Martins-Filho, Michael Cabanero, Hirotsugu Notsuda, Ni Liu, Christine Ng, Nikolina Radulovich, Ruoshi Shi
Supplementary Data Table S1, 3-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad664809adbc53e2b5a1f2cb59afe6a8
https://doi.org/10.1158/1078-0432.22474499.v1
https://doi.org/10.1158/1078-0432.22474499.v1
Autor:
Ming-Sound Tsao, Nadeem Moghal, Geoffrey Liu, Benjamin Haibe-Kains, Nhu-An Pham, Laura Tamblyn, Yu-Hui Wang, Ming Li, Joshua C. Rosen, Arvind Singh Mer, Quan Li, Vibha Raghavan, Sebastiao N. Martins-Filho, Michael Cabanero, Hirotsugu Notsuda, Ni Liu, Christine Ng, Nikolina Radulovich, Ruoshi Shi
Purpose:Non–small cell lung cancer (NSCLC) is the most common cause of cancer-related deaths worldwide. There is an unmet need to develop novel clinically relevant models of NSCLC to accelerate identification of drug targets and our understanding o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048c8862d3e9f390a18a9389b4defa6f
https://doi.org/10.1158/1078-0432.c.6528803
https://doi.org/10.1158/1078-0432.c.6528803
Autor:
Ming-Sound Tsao, Nadeem Moghal, Frances A. Shepherd, Nhu-An Pham, Michael Cabanero, Shirley Tam, Vibha Raghavan, Ming Li, Ruoshi Shi
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bffaed610eef3dc0693f1e775440b69
https://doi.org/10.1158/1078-0432.22469942
https://doi.org/10.1158/1078-0432.22469942
Autor:
Ming-Sound Tsao, Nadeem Moghal, Frances A. Shepherd, Nhu-An Pham, Michael Cabanero, Shirley Tam, Vibha Raghavan, Ming Li, Ruoshi Shi
Supplementary Figure S1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3075595148a70acc4ce8f1f08e1f20f
https://doi.org/10.1158/1078-0432.22469945.v1
https://doi.org/10.1158/1078-0432.22469945.v1