Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial

Autor: Belle-Isle, Jasmin, Nadeau, Jerome, Killorn, William, Francoeur, Bruno, Millaire, Emilie, Pek, Bonavuth, Ferguson, Murdo, Maltais, Francois, Killian, Kieran, Mazza, Giuseppe, Melenka, Lyle, Walker, Brandie, Bergeron, Celine, FitzGerald, John, Weinreich, Ulla Møller, Bendstrup, Elisabeth, Porsbjerg, Celeste, Ulrik, Charlotte, Titlestad, Ingrid, Meyer, Christian, Hilberg, Ole, Couturaud, Francis, Andrejak, Claire, Bourdin, Arnaud, Devouassoux, Gilles, Pepin, Jean-Louis, Chanez, Pascal, Cavailles, Arnaud, Eich, Andreas, Ludwig-Sengpiel, Andrea, Watz, Henrik, Schultz, Thomas, Bar-Shai, Amir, Wand, Ori, Adir, Yochai, Berkman, Neville, Fink, Gershon, Shitrit, David, Izbicki, Gabriel, Raviv, Yael, Wielders, Pascal, Goosens, Martijn, Heller-Baan, Roxane, in't Veen, Johannes, Custers, Frank, Oh, Yeon-Mok, Lee, YongChul, Kim, Jaeyeol, Yoo, Kwang-Ha, Park, Jung-Won, Lee, Sang Haak, Ahn, Joong Hyun, Lee, Sook Young, Kim, Jin Woo, Lee, Kwan Ho, Caballero, Luis Mateos, Naval Sendra, Elsa, Ramos Barbón, David, Velasco Garrido, José Luis, Alcázar Navarrete, Bernardino, Saralaya, Dinesh, Crooks, Michael, Shah, Pallav, Chaudhuri, Rekha, de Soyza, Anthony, Nordstrom, Monica, Dwarakanath, Akshay, Weinstein, Steven, Pham, David, Mitchell, John, Spangenthal, Selwyn, Surdulescu, Sever, Denenberg, Michael, Alpizar, Sady, Maybee, David, Moriarty, Timothy, Fakih, Faisal, Beasley, Richard, Heuer, Marvin, Patel, Amit, Dorf, Jeffrey, Martinez, Rafael, Kureishy, Shahrukh, Klein, Ryan, Hewitt, Mitzie, Cole, Jeremy, Robinette, Emory, Cordasco, Edward, Garver, Robert, Criner, Gerard, Sciurba, Frank, Kerwin, Edward, Lucksinger, Gregg, Delgado, John, Russian, David, Chupp, Geoffrey, Singh, Dave ^a, Brightling, Christopher E ^b, Rabe, Klaus F ^{c, d, e}, Han, MeiLan K ^f, Christenson, Stephanie A ^g, Drummond, M Bradley ^h, Papi, Alberto ⁱ, Pavord, Ian D ^j, Molfino, Nestor A ^k, Almqvist, Gun ^l, Kotalik, Ales ^m, Hellqvist, Åsa ⁿ, Gołąbek, Monika ^o, Sindhwani, Navreet S ^p, Ponnarambil, Sandhia S ^{q, *}

Publikováno v: In The Lancet Respiratory Medicine January 2025 13(1):47-58