Výsledky vyhledávání - "Nadège Touche"

Akademický článek

The Iron Maiden. Cytosolic Aconitase/IRP1 Conformational Transition in the Regulation of Ferritin Translation and Iron Hemostasis

Autor: Cécilia Hognon, Emmanuelle Bignon, Guillaume Harle, Nadège Touche, Stéphanie Grandemange, Antonio Monari

Publikováno v: Biomolecules, Vol 11, Iss 9, p 1329 (2021)

Maintaining iron homeostasis is fundamental for almost all living beings, and its deregulation correlates with severe and debilitating pathologies. The process is made more complicated by the omnipresence of iron and by its role as a fundamental comp

Externí odkaz: https://doaj.org/article/07f94792d1804e92a9a1487253e1647a

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Data from DDB2: A Novel Regulator of NF-κB and Breast Tumor Invasion

Autor: Philippe Becuwe, Stéphanie Grandemange, François Plénat, Joseph Abecassis, Lionel Domenjoud, Sonia Ledrappier, Alain C. Jung, Denise Thiebaut, Emilie Brunner, Vanessa Besancenot, Claire Barbieux, Sophie Pinel, Nadège Touche, Rémi Klotz, Marie Ennen

The DNA repair protein damaged DNA-binding 2 (DDB2) has been implicated in promoting cell-cycle progression by regulating gene expression. DDB2 is selectively overexpressed in breast tumor cells that are noninvasive, but not in those that are invasiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c44ef7f7a196f488779093148069200
https://doi.org/10.1158/0008-5472.c.6505925

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Supplementary Figures 1-5 from DDB2: A Novel Regulator of NF-κB and Breast Tumor Invasion

PDF - 636K, Supplementary Figure 1: DDB2 reduces migration abilities of the aggressive breast tumor MDA-MB231 cell line in wound healing-induced migration assay. Supplementary Figure 2: Knockdown of DDB2 expression induces migratory and invasive abil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5febfab0691993331d7a0bf2aaac5f
https://doi.org/10.1158/0008-5472.22401815

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Supplementary Tables 1-3 from DDB2: A Novel Regulator of NF-κB and Breast Tumor Invasion

PDF - 86K, Supplementary Table 1: Primers for RT-PCR, ChIP analysis and EMSA. Supplementary Table 2: Data from flow cytometry analysis showing the distribution of the quantified invasive cells in lungs from mice injected with MDA Neo or DDB2 cells. S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5cb11a51af719a9675fe3ce25698be
https://doi.org/10.1158/0008-5472.22401806

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Regulation of the high basal expression of the manganese superoxide dismutase gene in aggressive breast cancer cells

Autor: Jean-Louis Merlin, Stéphanie Grandemange, Philippe Becuwe, Emilie Brunner, Lionel Domenjoud, Marie Ennen, Vanessa Minig, Nadège Touche, Vanessa Besancenot

Publikováno v: Free Radical Biology and Medicine. 50:1771-1779

A high basal expression of manganese superoxide dismutase (MnSOD) has been reported in aggressive breast cancer cells, according to an unknown mechanism, and contributes to their invasive abilities. Here, we report the involvement of Sp1 and nuclear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb858c218bb949507589869a825969c
https://doi.org/10.1016/j.freeradbiomed.2011.03.013

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PO-164 Identification of the heterogeneous nuclear ribonucleoprotein K/J (hnRNP K/J) as a repressor of the inhibitor kappa B alpha (IκBα) gene in aggressive breast cancer cells

Autor: Nadège Touche, Philippe Becuwe, G. Drouot, Vanessa Besancenot, A. Taverniers, Stéphanie Grandemange

Publikováno v: ESMO Open. 3:A291

Introduction Advanced breast cancers do not respond well to therapies and represent a relevant focus for studying molecular mechanisms involved in the tumour progression and drug resistance. The transcription factor NF-κB is often activated constitu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e26026bdaa6d828b3b729a1e8ec163a
https://doi.org/10.1136/esmoopen-2018-eacr25.686

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Functional Characterization of the Human Platelet Glycoprotein V Gene Promoter: A Specific Marker of Late Megakaryocytic Differentiation

Autor: Adeline Lepage, Georges Uzan, Nadège Touche, Martine Morales, Jean-Pierre Cazenave, François Lanza, Corinne de la Salle

Publikováno v: Blood. 94:3366-3380

Glycoprotein V (GPV), a subunit of the platelet GPIb-V-IX receptor for von Willebrand factor and thrombin, is specifically found in platelets and mature megakaryocytes. Studies of the GPV gene can therefore provide insight into the mechanisms governi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f5d3799db522f480f3062a4313a473
https://doi.org/10.1182/blood.v94.10.3366.422k35_3366_3380

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DDB2: a novel regulator of NF-κB and breast tumor invasion

Autor: Vanessa Besancenot, Alain C. Jung, Joseph Abecassis, Emilie Brunner, Rémi Klotz, Stéphanie Grandemange, Sophie Pinel, Philippe Becuwe, Marie Ennen, Denise Thiebaut, François Plénat, Sonia Ledrappier, Claire Barbieux, Lionel Domenjoud, Nadège Touche

Publikováno v: Cancer Research
Cancer Research, American Association for Cancer Research, 2013, 73 (16), pp.5040-5052. ⟨10.1158/0008-5472.CAN-12-3655⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354ad3c461e20b020c8fe81064a7bb28
https://hal.archives-ouvertes.fr/hal-00921880

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Genetic analysis of peroxisome proliferator-activated receptor gamma1 splice variants in human colorectal cell lines

Autor: Cathy, Fiatte, Cécile, Huin, Isabelle, Bertin, Thécla, Lesuffleur, Arnaud, Pluvinet, Nadège, Touche, François, Plénat, Michel, Dauça, Lionel, Domenjoud, Hervé, Schohn

Publikováno v: International journal of oncology. 29(6)

Peroxisome proliferator-activated receptor gamma (PPARgamma) is a member of the nuclear hormone receptor family. In colon, this transcription factor is involved in differentiation of absorptive cells. PPARgamma participates also in colon carcinogenes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c2583edb6db8981aa61c4d568d454d6c
https://pubmed.ncbi.nlm.nih.gov/17089002

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