Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nadav Ben Haim"'
Autor:
Sandrine Soubes, Pamela Ellis, Sarah Burbridge, Kyoji Ohyama, Daniel B. Constam, Canhe Chen, Kim Dale, Marysia Placzek, Nadav Ben-Haim, Michael M. Shen
Publikováno v:
Development (Cambridge, England)
The secreted glycoprotein sonic hedgehog (Shh) is expressed in the prechordal mesoderm, where it plays a crucial role in induction and patterning of the ventral forebrain. Currently little is known about how Shh is regulated in prechordal tissue. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90b2735e0ebd1a0f2713c195e680ef1
https://eprints.whiterose.ac.uk/106404/1/3821.full.pdf
https://eprints.whiterose.ac.uk/106404/1/3821.full.pdf
Autor:
Daniel Mesnard, Luca Pescatore, Nadav Ben-Haim, Cindy C. Lu, Daniel B. Constam, Elizabeth J. Robertson, Felix Naef, Mirko Bischofberger, Marcela Guzman-Ayala
Publikováno v:
Developmental Cell. 11(3):313-323
During early mouse development, the subtilisin-like proprotein convertases (SPC) Furin and PACE4 pattern the primitive ectoderm and visceral endoderm, presumably by activating the TGFss-related Nodal precursor. Here, mutation of the SPC motif provide
Autor:
Nadav Ben-Haim, Inna Berman, Bella Kalderon, Rachel Hertz, Jacob Bar-Tana, Friedhelm Schroeder, Naama Eldad, Anca D. Petrescu
Publikováno v:
Journal of Biological Chemistry. 278:22578-22585
Missense mutations of the ligand binding domain of hepatocyte nuclear factor (HNF)-4alpha result in maturity onset diabetes of the young (MODY)-1. We show here that MODY-1 as well as Gln-185 missense mutants of the ligand binding domain of HNF-4alpha
Autor:
Karine Roy, Daniel B. Constam, Nadav Ben Haim, J. Ann Le Good, Marcela Guzman, Séverine Beck, Friedrich Beermann
Publikováno v:
Nature Cell Biology. 4:981-985
During gastrulation, a cascade of inductive tissue interactions converts pre-existing polarity in the mammalian embryo into antero-posterior pattern. This process is triggered by Nodal, a protein related to transforming growth factor-beta (TFG-beta)
Autor:
Nadav Ben-Haim, Klaus Scheffler, Pavel Broz, Francesco Santini, Wolfgang Meier, Patrick Hunziker, Stephan Marsch
Publikováno v:
European Journal of Nanomedicine
Gadolinium-based contrast agents for imaging of cellular or subcellular compartments by clinical magnetic resonance imaging (MRI) currently lack a satisfying signal-to-noise ratio and acceptable target specificity. Water-soluble enzyme nanoreactors b
Publikováno v:
Nano letters. 8(5)
Cell organelles are subcellular structures characterized by specific functionalities. They often consist of membrane-delineated microcompartments with a unique set of enzymes. Here we report the design of synthetic organelles based on nanometer-sized
Autor:
Stephan Marsch, Wolfgang Meier, Nadav Ben-Haim, Patrick Hunziker, Pavel Broz, Mariusz Grzelakowski
Publikováno v:
Journal of cardiovascular pharmacology. 51(3)
Ruptures of macrophage-rich atherosclerotic plaques in the coronary arteries are the main reason for heart attack. Targeted therapeutic interventions with an inhibitory effect on the macrophages promise to be beneficial, but currently available drugs
Autor:
Patrick Hunziker, Nadav Ben-Haim, Wolfgang Meier, Stephan Marsch, Joerg Ziegler, Sergey Driamov, Pavel Broz
Publikováno v:
Nano letters. 6(10)
To develop an intelligent sensor-effector functionality on the nanoscale, a pH-switchable, controlled nanoreactor based on amphiphilic copolymer membranes was built. The nanovesicles were equipped with bacterial transmembrane ompF pore proteins and t
Publikováno v:
Nano Letters; Apr2008, Vol. 8 Issue 5, p1368-1373, 6p
Autor:
Nadav Ben-Haim, Séverine Beck, Antonio J. Giraldez, Daniel B. Constam, Yu Chen, Katherine Joubin, Alexander F. Schier, J. Ann Le Good
Publikováno v:
Current Biology. (1):31-36
Secreted TGFβ proteins of the Nodal family pattern the vertebrate body axes and induce mesoderm and endoderm [1]. Nodal proteins can act as morphogens [2], but the mechanisms regulating their activity and signaling range are poorly understood. In pa