Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nada S. Daifalla"'
Publikováno v:
Redox Report, Vol 28, Iss 1 (2023)
ABSTRACTObjective: Methotrexate (MTX) is a drug used in the treatment of cancer and autoimmune disorders; however, its clinical use is limited because of serious side effects including renal toxicity. This study aimed to investigate the protective ef
Externí odkaz:
https://doaj.org/article/33b4bdb1fa6d49dc989395c5efbf6cae
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
We assessed the immune response against recombinant proteins of two related, albeit functionally different, peroxidoxins from Leishmania donovani: peroxidoxin 1 (LdPxn1) and peroxidoxin 2 (LdPxn2) in BALB/c mice. We also evaluated the effect of coadm
Externí odkaz:
https://doaj.org/article/f1d57d860f534619ba83202136b79011
Publikováno v:
BioMed Research International, Vol 2017 (2017)
BioMed Research International
BioMed Research International
Growing evidence shows that antioxidant proteins ofLeishmaniacould be used as vaccine candidates. In this study, we report the efficacy ofLeishmania donovaniiron superoxide dismutase B1 (LdFeSODB1) as a vaccine antigen in BALB/c mice in a DNA-protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c553a421bb8ece85591ae616e690fedb
https://doaj.org/article/2c81d02b00b143f484a2d3ef41a67791
https://doaj.org/article/2c81d02b00b143f484a2d3ef41a67791
Publikováno v:
Experimental Parasitology. 131:317-324
In this study, we tested the protective efficacy of recombinant Leishmania donovani iron superoxide dismutase B1 (SODB1) against Leishmania major infection in BALB/c mice. Mice were challenged with L. major 3 weeks after the second boost immunization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0426f7392d8d14a255e5031e5d65c35a
https://doi.org/10.1016/j.exppara.2012.05.002
https://doi.org/10.1016/j.exppara.2012.05.002
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2015 (2015)
Journal of Immunology Research, Vol 2015 (2015)
We assessed the immune response against recombinant proteins of two related, albeit functionally different, peroxidoxins fromLeishmania donovani: peroxidoxin 1 (LdPxn1) and peroxidoxin 2 (LdPxn2) in BALB/c mice. We also evaluated the effect of coadmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e878b83a137fe3f81a3c6b100c158c
http://europepmc.org/articles/PMC4562178
http://europepmc.org/articles/PMC4562178
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 12, p e3391 (2014)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background To date, no universally effective and safe vaccine has been developed for general human use. Leishmania donovani Peroxidoxin-1 (LdPxn-1) is a member of the antioxidant family of proteins and is predominantly expressed in the amastigote sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7aac4f643505f37d676bcc58862f4a
http://europepmc.org/articles/PMC4263403?pdf=render
http://europepmc.org/articles/PMC4263403?pdf=render
Autor:
Steven G. Reed, Yasir A. W. Skeiky, Ajay Bhatia, Nada S. Daifalla, Roberto Badaró, Shyian Jen
Publikováno v:
Molecular and biochemical parasitology. 102(2)
We report here the molecular cloning and characterization of two related hydrophilic antigens of Leishmania chagasi. These two antigens have predicted molecular weights of approximately 9 and 26 kDa and detect antibodies in sera of patients with kala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc18e8d74990760a05ff70558116b331
https://pubmed.ncbi.nlm.nih.gov/10498181
https://pubmed.ncbi.nlm.nih.gov/10498181
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 12, p e3391 (2014)
To date, no universally effective and safe vaccine has been developed for general human use. Leishmania donovani Peroxidoxin-1 (LdPxn-1) is a member of the antioxidant family of proteins and is predominantly expressed in the amastigote stage of the p
Externí odkaz:
https://doaj.org/article/c10000ce6fa643879365fd1f346df212