Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Nada Božina"'
Autor:
Tamara Božina, Lana Ganoci, Ena Karačić, Livija Šimičević, Majda Vrkić-Kirhmajer, Iva Klarica-Domjanović, Tena Križ, Zrinka Sertić, Nada Božina
Publikováno v:
Annals of Human Biology, Vol 49, Iss 7-8, Pp 323-331 (2022)
Background Organic anion-transporting polypeptide 1B1 (OATP1B1) and the ATP-binding cassette subfamily G member 2, ABCG2, are important transporters involved in the transport of endogenous substrates and xenobiotics, including drugs. Genetic polymorp
Externí odkaz:
https://doaj.org/article/ba302c8799c148b68bd254980828ad93
Publikováno v:
Liječnički vjesnik, Vol 145, Iss Supp 8, Pp 43-43 (2023)
Tardive dyskinesia is a neurological disorder characterized by involuntary, repetitive mo-vements of the face, tongue, and limbs, which may result from a long-term use of antip-sychotics.
Externí odkaz:
https://doaj.org/article/5747840d5f6f4ed99d7fd85366c238a6
Publikováno v:
Annals of Human Biology, Vol 44, Iss 3, Pp 287-294 (2017)
Background: Apolipoprotein E has an important role in lipid metabolism and adipocyte activity and apo E gene (APOE) might serve as a potential determinant of metabolic syndrome (MetS). Aim: The aim of the presented study was to investigate the associ
Externí odkaz:
https://doaj.org/article/38265fdd5b054fb1a84d052dbc8de37e
Autor:
Agata Ladić, Nada Božina, Vladimir Borzan, Marko Brinar, Boris Vucelić, Silvija Čuković-Čavka
Publikováno v:
Acta Clinica Croatica, Vol 55., Iss 1., Pp 16-22 (2016)
Thiopurine S-methyltransferase (TPMT) is an enzyme that converts thiopurine drugs into inactive metabolites. Over 20 variant TPMT-encoding alleles, which cause reduced enzymatic activity, have been discovered so far. Our aim was to investigate the fr
Externí odkaz:
https://doaj.org/article/1a0256dd96ae46f5b2858cc68e43c08d
Autor:
Tatjana Škarić-Jurić, Željka Tomas, Matea Zajc Petranović, Nada Božina, Nina Smolej Narančić, Branka Janićijević, Marijana Peričić Salihović
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207671 (2018)
The products of the polymorphic ADME genes are involved in Absorption, Distribution, Metabolism, and Excretion of drugs. The pharmacogenetic data have been studied extensively due to their clinical importance in the appropriate drug prescription, but
Externí odkaz:
https://doaj.org/article/ddc7a70d888b4cf3bbac9cf08b9aa028
Autor:
Lucija Lešnjaković, Lana Ganoci, Ivan Bilić, Livija Šimičević, Iva Mucalo, Stjepko Pleština, Nada Božina
Publikováno v:
Pharmacogenomics. 24:93-106
Fluoropyrimidines (FPs) are antineoplastic drugs widely used in the treatment of various solid tumors. Nearly 30% of patients treated with FP chemotherapy experience severe FP-related toxicity, and in some cases, toxicity can be fatal. Patients with
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 47:1461-1465
What is known and objective: Tacrolimus (TAC) is an immunosuppressant with large interpatient pharmacokinetic variability and a narrow therapeutic index. We report a case of acute cellular rejection (ACR) type IB with insufficient TAC blood concentra
Autor:
Ivana Šušak Sporiš, Nada Božina, Iva Klarica Domjanović, Davor Sporiš, Silvio Bašić, Ivana Marković, Mila Lovrić, Lana Ganoci, Vladimir Trkulja
To test the hypothesis that the effect of valproate on dose-adjusted lamotrigine troughs was moderated by the ABCG2 c.421C>A (rs2231142) polymorphism, we conducted two studies in adults with epilepsy. Since Study 2 replicated the findings of Study 1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a77ba0b07d64c9774d379d2eeabbcb6b
https://doi.org/10.22541/au.167146513.36768419/v1
https://doi.org/10.22541/au.167146513.36768419/v1
Autor:
Nada Božina, Ivana Šušak Sporiš, Iva Klarica Domjanović, Lana Ganoci, Livija Šimičević, Mila Lovrić, Zrinka Čolak Romić, Željka Petelin Gadže, Vladimir Trkulja
Purpose. To estimate whether epilepsy patients with variant UGT2B7 -161C>T(rs7668258) or UGT1A4*3 c.142T>G(rs2011425) alleles differ from their wild-type (wt) peers in exposure to lamotrigine. Methods. Consecutive adults on lamotrigine monotherapy or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7efc13c7e0c0437f2bca44b09af56a22
https://doi.org/10.21203/rs.3.rs-2297781/v1
https://doi.org/10.21203/rs.3.rs-2297781/v1
Autor:
Ana Borić-Bilušić, Nada Božina, Zdenka Lalić, Mila Lovrić, Sandra Nađ-Škegro, Luka Penezić, Karmela Barišić, Vladimir Trkulja
Introduction. Polymorphism ABCG2 c.421C > A (rs2231142) results in a reduced activity of the important drug efflux transporter breast cancer resistance protein (BCRP/ABCG2). One study suggested that it may affect enterohepatic recirculation of mycoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a2a0dff8d39ef89fb0f4c25d52449fb
https://doi.org/10.21203/rs.3.rs-2247771/v1
https://doi.org/10.21203/rs.3.rs-2247771/v1