Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Nada Alaaeddine"'
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-11 (2022)
Abstract Background Living organisms are continuously exposed to multiple internal and external stimuli which may influence their emotional, psychological, and physical behaviors. Stress can modify brain structures, reduces functional memory and resu
Externí odkaz:
https://doaj.org/article/ae1725883b8e4c1a97d06db7768b7c7b
Autor:
Stephanie Antoun, David Atallah, Roula Tahtouh, Nada Alaaeddine, Malak Moubarak, Abir Khaddage, Eliane Nasr Ayoub, George Chahine, George Hilal
Publikováno v:
Cancer Cell International, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background p53 is a tumor suppressor and key regulator of glycolysis in cancer cells, however highly mutated in tumors. In ovarian cancer, studies concerning p53 mutations focus on the DNA binding domain since the majority of hotspot mutatio
Externí odkaz:
https://doaj.org/article/00521658b23741eca70c31bb9bbcae0f
Autor:
Souraya Sayegh, Oula El Atat, Katy Diallo, Benjamin Rauwel, Yannick Degboé, Etienne Cavaignac, Arnaud Constantin, Alain Cantagrel, Viviane Trak-Smayra, Nada Alaaeddine, Jean-Luc Davignon
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/7c69462cb68e4734b2466f294bd55561
Autor:
Souraya Sayegh, Oula El Atat, Katy Diallo, Benjamin Rauwel, Yannick Degboé, Etienne Cavaignac, Arnaud Constantin, Alain Cantagrel, Viviane Trak-Smayra, Nada Alaaeddine, Jean-Luc Davignon
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Introduction: Adipose-derived mesenchymal stem cells (ADSC) have been shown to have remarkable immune-modulating effects. However, their efficacy in clinical trials has yet to be fully demonstrated. This could be due to a lack of a proper inflammator
Externí odkaz:
https://doaj.org/article/a0651ad942244e82b52e5f860860007d
Autor:
Ammad Ahmad Farooqi, Rukset Attar, Uteuliyev Yerzhan Sabitaliyevich, Nada Alaaeddine, Damião Pergentino de Sousa, Baojun Xu, William C. Cho
Publikováno v:
Cancers, Vol 12, Iss 8, p 2159 (2020)
There has been a paradigm shift in our understanding about the multifaceted nature of cancer, and a wealth of information has revealed that single-target drugs are not good enough to provide satisfactory clinical outcomes and therapeutic effects for
Externí odkaz:
https://doaj.org/article/dfafd4d5e7314203880214909ccb9c9e
Autor:
Nadine Mahfouz, Roula Tahtouh, Nada Alaaeddine, Joelle El Hajj, Riad Sarkis, Ray Hachem, Issam Raad, George Hilal
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179202 (2017)
Targeting angiogenesis has been considered a promising treatment of choice for a large number of malignancies, including gastrointestinal cancers. Bevacizumab is an anti-vascular endothelial growth factor (anti-VEGF) being used for this purpose. Howe
Externí odkaz:
https://doaj.org/article/b00c87832ecc47bf8b9745bd140da1a4
Autor:
Meriem Bachsais, Nadim Naddaf, Daniel Yacoub, Suzanne Salti, Nada Alaaeddine, Fawzi Aoudjit, Ghada S Hassan, Walid Mourad
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158987 (2016)
CD154, a critical regulator of the immune response, is usually associated with chronic inflammatory, autoimmune diseases as well as malignant disorders. In addition to its classical receptor CD40, CD154 is capable of binding other receptors, members
Externí odkaz:
https://doaj.org/article/f62bd0ec895d460482607cf7326f0ea2
Autor:
Oula El Atat, Diane Antonios, George Hilal, Nabil Hokayem, Joelle Abou-Ghoch, Hussein Hashim, Rim Serhal, Clara Hebbo, Mayssam Moussa, Nada Alaaeddine
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162332 (2016)
The use of adipose-derived stem cells (ADSC) in regenerative medicine is rising due to their plasticity, capacity of differentiation and paracrine and trophic effects. Despite the large number of cells obtained from adipose tissue, it is usually not
Externí odkaz:
https://doaj.org/article/23c5c6ff08f349a2bda96459ae4a1a11
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1051 (2018)
Substantial fraction of high-quality information is continuously being added into the existing pool of knowledge related to the biology of telomeres. Based on the insights gleaned from decades of research, it is clear that chromosomal stability needs
Externí odkaz:
https://doaj.org/article/4719718e2b3d42f9b348965052c9f2fe
Autor:
Roula Tahtouh, Anne-Sophie Azzi, Nada Alaaeddine, Soulaima Chamat, Hasnaa Bouharoun-Tayoun, Layal Wardi, Issam Raad, Riad Sarkis, Najibe Abou Antoun, George Hilal
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119512 (2015)
Alpha-fetoprotein (AFP) is a diagnostic marker for hepatocellular carcinoma (HCC). A direct relationship between poor prognosis and the concentration of serum AFP has been observed. Telomerase, an enzyme that stabilizes the telomere length, is expres
Externí odkaz:
https://doaj.org/article/67d3c710a71641b59c8fb416b112d4cf