Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nada Al Eisa"'
Autor:
David Smith, Nada Al Eisa, Isabelle Williams, Wolfram Haller, Sumeet Pandey, Alicia Chan, Hien Quoc Huynh, Holm H. Uhlig, Ruth Bettels, Gesche Düeker, Chinenye R. Dike, Laurent Peyrin-Biroulet, Thorsten Marquardt, Catherine DeGeeter, Frances M. Platt, Nick Platt, Tobias Schwerd
Publikováno v:
Wellcome Open Research, Vol 7 (2022)
Background: Blockade of tumour necrosis factor (anti-TNF) is effective in patients with Crohn’s Disease but has been associated with infection risk and neurological complications such as demyelination. Niemann-Pick disease Type C1 (NPC1) is a lysos
Externí odkaz:
https://doaj.org/article/d818f29e0e294020a0531d205c8fdb93
Autor:
Paul Fineran, Emyr Lloyd-Evans, Nathan A. Lack, Nick Platt, Lianne C. Davis, Anthony J. Morgan, Doris Höglinger, Raju Venkata V. Tatituri, Simon Clark, Ian M. Williams, Patricia Tynan, Nada Al Eisa, Evgeniya Nazarova, Ann Williams, Antony Galione, Daniel S. Ory, Gurdyal S. Besra, David G. Russell, Michael B. Brenner, Edith Sim, Frances M. Platt
Publikováno v:
Wellcome Open Research, Vol 1 (2017)
Background. Tuberculosis remains a major global health concern. The ability to prevent phagosome-lysosome fusion is a key mechanism by which intracellular mycobacteria, including Mycobacterium tuberculosis, achieve long-term persistence within host c
Externí odkaz:
https://doaj.org/article/14691c8505704db9a2e77b48b84d36f2
Autor:
Ian M. Williams, Kerri-Lee Wallom, David A. Smith, Nada Al Eisa, Claire Smith, Frances M. Platt
Publikováno v:
Neurobiology of Disease, Vol 67, Iss , Pp 9-17 (2014)
Objectives: Niemann–Pick disease type C (NPC) is a neurodegenerative lysosomal storage disorder characterised by the storage of multiple lipids, reduced lysosomal calcium levels, impaired late endosome:lysosome fusion and neuroinflammation. NPC is
Externí odkaz:
https://doaj.org/article/8fac83bf8d48468e83cd69767942c630
Autor:
Paul Fineran, Emyr Lloyd-Evans, Nathan A. Lack, Nick Platt, Lianne C. Davis, Anthony J. Morgan, Doris Höglinger, Raju Venkata V. Tatituri, Simon Clark, Ian M. Williams, Patricia Tynan, Nada Al Eisa, Evgeniya Nazarova, Ann Williams, Antony Galione, Daniel S. Ory, Gurdyal S. Besra, David G. Russell, Michael B. Brenner, Edith Sim, Frances M. Platt
Publikováno v:
Wellcome Open Research, Vol 1 (2016)
Background. Tuberculosis remains a major global health concern. The ability to prevent phagosome-lysosome fusion is a key mechanism by which intracellular mycobacteria, including Mycobacterium tuberculosis, achieve long-term persistence within host c
Externí odkaz:
https://doaj.org/article/6b137bbdd4a0445c9a31d3854f892721
Autor:
Elena-Raluca Nicoli, Nada Al Eisa, Celine V M Cluzeau, Christopher A Wassif, James Gray, Kathryn R Burkert, David A Smith, Lauren Morris, Stephanie M Cologna, Cody J Peer, Tristan M Sissung, Constantin-Daniel Uscatu, William D Figg, William J Pavan, Charles H Vite, Forbes D Porter, Frances M Platt
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152007 (2016)
Niemann-Pick type C (NPC) disease is a neurodegenerative lysosomal storage disease caused by mutations in either the NPC1 or NPC2 gene. NPC is characterised by storage of multiple lipids in the late endosomal/lysosomal compartment, resulting in cellu
Externí odkaz:
https://doaj.org/article/a33ecbb75c804f209699d9546d139a51
Autor:
Isabelle Williams, Sumeet Pandey, Wolfram Haller, Hien Quoc Huynh, Alicia Chan, Gesche Düeker, Ruth Bettels, Laurent Peyrin-Biroulet, Chinenye R. Dike, Catherine DeGeeter, David Smith, Nada Al Eisa, Nick Platt, Thorsten Marquardt, Tobias Schwerd, Frances M. Platt, Holm H. Uhlig
Publikováno v:
Wellcome Open Research. 7:11
Background: Blockade of tumour necrosis factor (anti-TNF) is effective in patients with Crohn’s Disease but has been associated with infection risk and neurological complications such as demyelination. Niemann-Pick disease Type C1 (NPC1) is a lysos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac3852b90c03115c7e77eb6fd63b584
https://doi.org/10.12688/wellcomeopenres.16986.1
https://doi.org/10.12688/wellcomeopenres.16986.1
Autor:
Simon Clark, Anthony J. Morgan, Raju V. V. Tatituri, Emyr Lloyd-Evans, Lianne C. Davis, Frances M. Platt, Edith Sim, Nick Platt, David G. Russell, Doris Höglinger, Nathan A. Lack, Evgeniya V. Nazarova, Ann Williams, Paul Fineran, Nada Al Eisa, Patricia W. Tynan, Gurdyal S. Besra, Daniel S. Ory, Antony Galione, Ian M. Williams, Michael B. Brenner
Publikováno v:
Turkish Journal of Urology
Wellcome Open Research
Wellcome Open Research
Background. Tuberculosis remains a major global health concern. The ability to prevent phagosome-lysosome fusion is a key mechanism by which intracellular mycobacteria, including Mycobacterium tuberculosis, achieve long-term persistence within host c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b936f9b841946ac13015e400844a45e2
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/2903
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/2903
Autor:
William J. Pavan, Tristan M. Sissung, Stephanie M. Cologna, William D. Figg, Kathryn R. Burkert, David Smith, Lauren Morris, C D Uscatu, Christopher A. Wassif, Nada Al Eisa, Charles H. Vite, Frances M. Platt, Cody J. Peer, Elena-Raluca Nicoli, James Gray, Céline Cluzeau, Forbes D. Porter
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152007 (2016)
PLoS ONE
PLoS ONE
Niemann-Pick type C (NPC) disease is a neurodegenerative lysosomal storage disease caused by mutations in either the NPC1 or NPC2 gene. NPC is characterised by storage of multiple lipids in the late endosomal/lysosomal compartment, resulting in cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbc9cf8eb84ba50b21e1269e7e8ddd2
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Arndt Rolfs, Guido Kramp, Hermann Mascher, Anne-Katrin Giese, Sabrina Eichler, Nada Al Eisa, Jan Lukas, Ulrike Grittner, Danielle te Vruchte, Forbes D. Porter, Mario Cortina-Borja, Frances M. Platt
Publikováno v:
Orphanet Journal of Rare Diseases
Background Lysosomal storage disorders (LSDs), are a heterogeneous group of rare disorders caused by defects in genes encoding for proteins involved in the lysosomal degradation of macromolecules. They occur at a frequency of about 1 in 5,000 live bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877168cb745a14421544a305a8608a34
Autor:
Kate Riddick, Clare Taylor, Yasmina Amraoui, Uma Ramaswami, Frances M. Platt, Xuntian Jiang, Daniel S. Ory, David Smith, Robin H. Lachmann, Daniel J. Sillence, Heiko Runz, Rohini Sidhu, Florian Rimmele, Caroline A. Hastings, Naomi Wright, Begona Arias, Anneliese O. Speak, Alison Cousins, Kerri L. Wallom, Michael Beck, Mylvaganam Jeyakumar, Louise Simmons, R. Hartung, Eugen Mengel, Christopher A. Wassif, Timothy M. Cox, Nicole M. Yanjanin, Danielle te Vruchte, Jackie Imrie, Christian J. Hendriksz, Nada Al Eisa, James E. Wraith, Arndt Rolfs, Mario Cortina-Borja, Elizabeth Jacklin, Forbes D. Porter
Lysosomal storage disorders (LSDs) occur at a frequency of 1 in every 5,000 live births and are a common cause of pediatric neurodegenerative disease. The relatively small number of patients with LSDs and lack of validated biomarkers are substantial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5488da15647e4ba656436a6876745a
http://hdl.handle.net/2086/9855
http://hdl.handle.net/2086/9855