Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications

Autor: Olivier Maury, Sophie Brasselet, Raphaël Tripier, Jean-Christophe Mulatier, Nadir Bettache, Marie Maynadier, Magali Gary-Bobo, Maryline Beyler, Christophe Nguyen, Alexei Grichine, Nadège Hamon, Chantal Andraud, Alain Duperray, Amandine Roux

Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2020, ⟨10.1021/jacs.0c03496⟩
Journal of the American Chemical Society, 2020, ⟨10.1021/jacs.0c03496⟩

International audience; In addition to the already described ligand L4a, two pyclen-based lanthanide chelators, L4b and L4c, bearing two specific picolinate two-photon antennas (tailor-made for each targeted metal) and one acetate arm arranged in a d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de392b14cfe2e36b60c2c6794ade903d
https://doi.org/10.1021/jacs.0c03496

Design of Polyazamacrocyclic Gd3+ Theranostic Agent Combining MRI and Two-Photon PDT

Autor: Laura Abad Galan, Nadège Hamon, Christophe Nguyen, Enikő Molnár, János Kiss, Jonathan Mendy, Kamel Hadj-Kaddour, Mélanie Onofre, György Trencsényi, Cyrille Monnereau, Maryline Beyler, Gyula Tircso, Magali Gary-Bobo, Olivier MAURY, Raphael Tripier

New “all-in-one” theranostic systems, combining a magnetic resonance imaging (MRI) contrast agent with a biphotonic photodynamic therapy (2P-PDT) photosensitiser generating cytotoxic singlet oxygen, were envisaged and synthesised. They are based

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675371c83e252a1da8d78206ca8d6a54
https://doi.org/10.26434/chemrxiv.13244447

Pyclen-Based Ligands Bearing Pendant Picolinate Arms for Gadolinium Complexation

Autor: Olivier Rousseaux, Gyula Tircsó, Gwladys Nizou, David Esteban-Gómez, Maryline Beyler, Nadège Hamon, Ferenc K. Kálmán, Olivier Fougère, Carlos Platas-Iglesias, Raphaël Tripier, Enikő Molnár

Publikováno v: Inorganic Chemistry
Inorganic Chemistry, American Chemical Society, 2021, ⟨10.1021/acs.inorgchem.0c03277⟩

International audience; We report the synthesis of two pyclen-based regioisomer ligands (pyclen = 3,6,9,15-tetraazabicyclo[9.3.1]pentadeca-1(15),11,13-triene) functionalized with picolinic acid pendant arms either at positions 3,9-pc2pa (L5) or 3,6-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef9fba75f457ae06b540f00771aa235
https://doi.org/10.26434/chemrxiv.13204070

Pyclen Based Ln(III) Complexes as Highly Luminescent Bioprobes for in Vitro and in Vivo 1P and 2P Bioimaging Applications

Autor: Nadège Hamon, Amandine Roux, Maryline Beyler, Jean-Christophe Mulatier, Chantal Andraud, Christophe Nguyen, Marie Maynadier, Nadir Bettache, Alain Duperray, Alexei Grichine, Sophie Brasselet, Magali Gary-Bobo, Olivier MAURY, Raphael Tripier

Two pyclen based lanthanide chelators, L4b and L4c, bearing two specific picolinate 2P antennas (tailor-made for each targeted metal) and one acetate arm arranged in a dissymmetrical manner, have been synthesized to form, with the already described l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b8b546ddcdd2e8242cd654bc5b8b1e
https://doi.org/10.26434/chemrxiv.12047532

Efficient luminescence control in dithienylethene functionalized cyclen macrocyclic lanthanide complexes

Autor: Olivier Galangau, Raphaël Tripier, Nadège Hamon, Lucie Norel, Hassan Al Sabea, Stéphane Rigaut, François Riobé, Olivier Maury

Publikováno v: Inorganic Chemistry Frontiers
Inorganic Chemistry Frontiers, Royal Society of Chemistry, 2020, 7 (16), pp.2979-2989. ⟨10.1039/D0QI00354A⟩
Inorganic Chemistry Frontiers, 2020, 7 (16), pp.2979-2989. ⟨10.1039/D0QI00354A⟩

International audience; We report the synthesis of an original ligand scaffold and the corresponding yttrium(III), europium(III) and ytterbium(III) complexes. All three compounds show reversible photochromism with high photo-conversions. Photolumines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831173f9652989fbaaa6cbb8a8773a7d
https://hal.univ-brest.fr/hal-02903552/document