Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nachen Yang"'
Autor:
Nachen Yang, Satyam P. Srivastav, Reazur Rahman, Qicheng Ma, Gargi Dayama, Sizheng Li, Madoka Chinen, Elissa P. Lei, Michael Rosbash, Nelson C. Lau
Publikováno v:
PLoS Genetics, Vol 18, Iss 3 (2022)
Genetic mechanisms that repress transposable elements (TEs) in young animals decline during aging, as reflected by increased TE expression in aged animals. Does increased TE expression during aging lead to more genomic TE copies in older animals? To
Externí odkaz:
https://doaj.org/article/f4b285347b0e44c1b2ba99134bd2bbcb
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40632 (2012)
The environment through which cells migrate in vivo differs considerably from the in vitro environment where cell migration is often studied. In vivo many cells migrate in crowded and complex 3-dimensional tissues and may use other cells as the subst
Externí odkaz:
https://doaj.org/article/e3751e202d61432b86049b4b3e2cffb0
Autor:
Gargi Dayama, Reazur Rahman, Qicheng Ma, Nelson C. Lau, Satyam P Srivastav, Elissa P. Lei, Michael Rosbash, Nachen Yang, Madoka Chinen
Genetic mechanisms that repress transposable elements (TEs) in young animals decline during aging, as reflected by increased TE expression in aged animals. Does increased TE expression during aging lead to more genomic TE copies in older animals? To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e63510679511c4255b3e370c1b5c3ed9
https://doi.org/10.1101/2021.01.08.425853
https://doi.org/10.1101/2021.01.08.425853
Autor:
Nachen Yang, Satyam Srivastav, Qicheng Ma, Reazur Rahman, Chinen, Madoka, Lei, Elissa, Lau, Nelson C.
Genetic mechanisms that strongly repress transposable elements (TEs) in young animals decline during aging because TE transcripts become reactivated. Does TE transcriptional reactivation during aging then alter and damage the genome? To test this hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26db9b1f936a61516b3ca4fea08de56f
Autor:
Alexey Khodjakov, David Pellman, Mijung Kwon, Shiwei Liu, Nachen Yang, Mark Mannino, Fioranna Renda
Publikováno v:
Nature. 561:551-555
Defects in the architecture or integrity of the nuclear envelope are associated with a variety of human diseases1. Micronuclei, one common nuclear aberration, are an origin for chromothripsis2, a catastrophic mutational process that is commonly obser
Defects in the architecture or integrity of the nuclear envelope (NE) are associated with a variety of human diseases1. Micronuclei, one common nuclear aberration, are an origin for chromothripsis2,3, a catastrophic mutational process commonly observ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021f04a9b622f7dc2b955d57e5caa023
https://doi.org/10.1101/263392
https://doi.org/10.1101/263392
Autor:
Shiwei, Liu, Mijung, Kwon, Mark, Mannino, Nachen, Yang, Fioranna, Renda, Alexey, Khodjakov, David, Pellman
Publikováno v:
Nature. 561(7724)
Defects in the architecture or integrity of the nuclear envelope are associated with a variety of human diseases
Autor:
Jeffrey G. Ault, Valentin Magidson, Raja Paul, Christopher B. O'Connell, Alexey Khodjakov, Alex Mogilner, Nachen Yang, Irina Tikhonenko, Bruce F. McEwen
Publikováno v:
Nature cell biology
Mitotic spindle formation relies on the stochastic capture of microtubules at kinetochores. Kinetochore architecture affects the efficiency and fidelity of this process with large kinetochores expected to accelerate assembly at the expense of accurac
Autor:
Bruce F. McEwen, Jie He, Jeffrey G. Ault, Christopher B. O'Connell, Alexey Khodjakov, Haixin Sui, Nachen Yang, Irina Tikhonenko, Valentin Magidson
Publikováno v:
The Journal of Cell Biology
Taxol induces extensive structural reorganization of the mammalian kinetochore; however, this reorganization is not sufficient to maintain a long-term mitotic arrest unless some of the kinetochores completely lose their attachment to microtubules.
Publikováno v:
Current Biology. 27:2718-2726.e4
Summary To test the directness of factors in initiating PIWI-directed gene silencing, we employed a Piwi-interacting RNA (piRNA)-targeted reporter assay in Drosophila ovary somatic sheet (OSS) cells [1]. This assay confirmed direct silencing roles fo