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pro vyhledávání: '"Nabila Bushra"'
Autor:
Kanchana Karunarathne, Nabila Bushra, Olivia Williams, Imad Raza, Laura Tirado, Diane Fakhre, Fadia Fakhre, Martin Muschol
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 230 (2023)
The deposition of dense fibril plaques represents the pathological hallmark for a multitude of human disorders, including many neurodegenerative diseases. Fibril plaques are predominately composed of amyloid fibrils, characterized by their underlying
Externí odkaz:
https://doaj.org/article/3eb5e53dd26a4c2abe22c79fd0ea7368
Publikováno v:
International Journal of Biological Macromolecules. 206:911-916
Conventional approaches to study ligand-receptor interactions using solution-state NMR often involve laborious sample preparation, isotopic labeling, and receptor reconstitution. Each of these steps remains challenging for membrane proteins such as G
Autor:
Chamani Niyangoda, Piyush Koria, Nabila Bushra, Kanchana Karunarathne, Fadia Fakhre, Jeremy Barton, Graham Strauss, Martin Muschol
Publikováno v:
RSC Chemical Biology
There is compelling evidence that small oligomeric aggregates, emerging during the assembly of amyloid fibrils and plaques, are important molecular pathogens in many amyloid diseases. While significant progress has been made in revealing the mechanis