Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nabila Boraie"'
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2717 (2022)
Oral tadalafil (TD) proved promising in treating pediatric pulmonary arterial hypertension (PAH). However, to ensure higher efficacy and reduce the systemic side effects, targeted delivery to the lungs through nebulization was proposed as an alternat
Externí odkaz:
https://doaj.org/article/e5797056d5dd49a1bf14c39a8b3b9e1b
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2527 (2022)
The study aim was to develop an intravesical delivery system of quercetin for bladder cancer management in order to improve drug efficacy, attain a controlled release profile and extend the residence time inside the bladder. Either uncoated or chitos
Externí odkaz:
https://doaj.org/article/f546ef0a4ff445abb720393cf4698138
Publikováno v:
Journal of Pharmaceutical Sciences. 110:2808-2822
Systemic rheumatoid arthritis (RA) regimens fail to attain effective drug level at the affected joints and are associated with serious side effects. Herein, an attempt made to improve therapeutic outcomes of both leflunomide (LEF) which is a disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b124e640c0e3a31471939a41f75684
https://doi.org/10.1016/j.xphs.2021.04.001
https://doi.org/10.1016/j.xphs.2021.04.001
Publikováno v:
Drug Delivery and Translational Research. 11:1037-1055
Despite the potent clinical efficacy of linezolid (LNZ) against drug-resistant tuberculosis, its safety and tolerability remain of major concern. Our objective is to develop antitubercular inhalable LNZ nano-embedded microparticles. In this context,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::461932501c12877a35ddf3e90138af84
https://doi.org/10.1007/s13346-020-00815-3
https://doi.org/10.1007/s13346-020-00815-3
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 1469, p 1469 (2021)
Volume 13
Issue 9
Pharmaceutics, Vol 13, Iss 1469, p 1469 (2021)
Volume 13
Issue 9
Skin restoration following full-thickness injury poses significant clinical challenges including inflammation and scarring. Medicated scaffolds formulated from natural bioactive polymers present an attractive platform for promoting wound healing. Gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b475b7455177229e3139273f92ac6d22
http://europepmc.org/articles/PMC8469322
http://europepmc.org/articles/PMC8469322
Publikováno v:
Pharmaceutical Development and Technology. 24:1083-1094
This study aims at improving the bioavailability of a poorly soluble phosphodiesterase-5 inhibitor; tadalafil (TD) via developing intranasal (IN) nanoemulsions (NEs). Optimum NE ingredients were selected based on solubility studies, emulsification te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09358fb34e47b78eb9c3a2c29f245b81
https://doi.org/10.1080/10837450.2019.1631846
https://doi.org/10.1080/10837450.2019.1631846
Publikováno v:
European Journal of Pharmaceutical Sciences. 125:151-162
With the non-selective vasodilating action, short half-life and first-pass metabolism of sildenafil (SC), local application in the lung for pulmonary arterial hypertension is of high demand. Although several nanosystems have been lately investigated,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e804bba987cedaa0b867cd6bd40fcb6
https://doi.org/10.1016/j.ejps.2018.10.003
https://doi.org/10.1016/j.ejps.2018.10.003
Publikováno v:
International journal of pharmaceutics. 567
Oral treatment of rheumatoid arthritis (RA) with the immunomodulator, leflunomide (LEF), is associated with systemic side effects namely immunosuppression and hepatotoxicity. Herein, attempts to improve LEF therapeutic outcomes via nanostructured lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260d5a56e4ee8f209909b9ba61fe1b07
https://pubmed.ncbi.nlm.nih.gov/31226475
https://pubmed.ncbi.nlm.nih.gov/31226475
Autor:
Ragwa M. Farid, Nancy Abdel Hamid Abou Youssef, Abeer Ahmed Kassem, Magda A. El-Massik, Nabila Boraie, Fatma Ahmed Ismail
Publikováno v:
International journal of pharmaceutics. 548(1)
This work aimed at designing efficient safe delivery system for intranasal (IN) brain targeting of the water soluble anti- migraine drug Almotriptan malate (ALM). Solid lipid nanoparticles (SLNs) were prepared by w/o/w double emulsion-solvent evapora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e020fce6a1884b470f8f90b7883ebeda
https://pubmed.ncbi.nlm.nih.gov/30033394
https://pubmed.ncbi.nlm.nih.gov/30033394
Publikováno v:
International Journal of Pharmaceutics. 486:297-305
The study demonstrates the feasibility of prolonging gastric residence time and release rate of metronidazole (Mz) by preparing floating raft system (FRS) using ion-sensitive in situ gel forming polymers. FRSs contained 3, 4, 5 and 0.5, 0.75, 1% w/v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba10e52e5322a8c75485123896b1ee35
https://doi.org/10.1016/j.ijpharm.2015.04.004
https://doi.org/10.1016/j.ijpharm.2015.04.004