Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nabil Georges Seidah"'
Autor:
Emilie Wong Chong, France-Hélène Joncas, Pierre Douville, Dimcho Bachvarov, Caroline Diorio, Frédéric Calon, Ann-Charlotte Bergeron, Jonatan Blais, Shuk On Annie Leung, Nabil Georges Seidah, Anne Gangloff
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Cancer cells need constant supplies of lipids to survive and grow. Lipid dependence has been observed in various types of cancer, including high-grade serous ovarian carcinomas (HGSOC), which is a lethal form of gynecological malignancy. ANG
Externí odkaz:
https://doaj.org/article/3e08325700c543e7b2a228d6e9b32a33
Autor:
Ben M, Brumpton, Lars G, Fritsche, Jie, Zheng, Jonas Bille, Nielsen, Maria, Mannila, Ida, Surakka, Humaira, Rasheed, Gunnhild Åberge, Vie, Sarah E, Graham, Maiken Elvestad, Gabrielsen, Lars Erik, Laugsand, Pål, Aukrust, Lars Johan, Vatten, Jan Kristian, Damås, Thor, Ueland, Imre, Janszky, John-Anker, Zwart, Ferdinand M, Van't Hooft, Nabil Georges, Seidah, Kristian, Hveem, Cristen, Willer, George Davey, Smith, Bjørn Olav, Åsvold
PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors reduce serum LDL (low-density lipoprotein) cholesterol (LDL-C) by increasing uptake in the liver. Although some long-term trials have evaluated their safety, broad investigations of out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4dea09494aab2f7896df38ffef20e85d
https://hdl.handle.net/10037/17282
https://hdl.handle.net/10037/17282
Autor:
Humaira Rasheed, Lars E. Laugsand, Thor Ueland, Ida Surakka, George Davey Smith, Ferdinand M. van't Hooft, Pål Aukrust, Kristian Hveem, Sarah E. Graham, Jie Zheng, Bjørn Olav Åsvold, Jan Kristian Damås, Cristen J. Willer, Ben Michael Brumpton, Lars G. Fritsche, Maiken Elvestad Gabrielsen, Gunnhild Åberge Vie, Maria Nastase Mannila, John-Anker Zwart, Jonas B. Nielsen, Lars J. Vatten, Imre Janszky, Nabil Georges Seidah
Publikováno v:
Circulation: Genomic and Precision Medicine. 12
Publikováno v:
Biochemical Journal. 360:127-134
The Portland α1-antitrypsin variant (α1-PDX) inhibits gp160 cleavage into gp120 and gp41 by different prohormone convertases (PCs) including furin, PC5 and PC7. Jurkat cells stably transfected with this inhibitor (J-PDX cells) and, as controls, Jur