Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Nabendu Pore"'
Autor:
Hemant K. Mishra, Kate J. Dixon, Nabendu Pore, Martin Felices, Jeffrey S. Miller, Bruce Walcheck
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer (NK) cells are innate cytotoxic lymphocytes that can recognize assorted determinants on tumor cells and rapidly kill these cells. Due to their anti-tumor effector functions and potential for allogeneic use, various NK cell platforms ar
Externí odkaz:
https://doaj.org/article/27002e9de420433699fba065559dac2a
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6688 (2020)
Sepsis is the culmination of hyperinflammation and immune suppression in response to severe infection. Neutrophils are critical early responders to bacterial infection but can become highly dysfunctional during sepsis and other inflammatory disorders
Externí odkaz:
https://doaj.org/article/0b0588aff54746819d9d0c366cdb3da6
Autor:
Nabendu Pore, Sanjoo Jalla, Zheng Liu, Brandon Higgs, Claudio Sorio, Aldo Scarpa, Robert Hollingsworth, David A. Tice, Emil Michelotti
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 6, Pp 473-480 (2015)
Reprogramming of energy metabolism is one of the emerging hallmarks of cancer. Up-regulation of energy metabolism pathways fuels cell growth and division, a key characteristic of neoplastic disease, and can lead to dependency on specific metabolic pa
Externí odkaz:
https://doaj.org/article/a83f7e43caf041d6865328ba74b733bc
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 11, Pp 889-895 (2006)
Glioblastomas are malignant brain tumors that are rarely curable, even with aggressive therapy (surgery, chemotherapy, radiation). Glioblastomas frequently display loss of PTEN and/or epidermal growth factor receptor activation, both of which activat
Externí odkaz:
https://doaj.org/article/bff242070e7e4d1589bf84f59965d45d
Autor:
George J Cerniglia, Nabendu Pore, Jeff H Tsai, Susan Schultz, Rosemarie Mick, Regine Choe, Xiaoman Xing, Turgut Durduran, Arjun G Yodh, Sydney M Evans, Cameron J Koch, Stephen M Hahn, Harry Quon, Chandra M Sehgal, William M F Lee, Amit Maity
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6539 (2009)
Epidermal growth factor receptor (EGFR) inhibitors have shown only modest clinical activity when used as single agents to treat cancers. They decrease tumor cell expression of hypoxia-inducible factor 1-alpha (HIF-1alpha) and vascular endothelial gro
Externí odkaz:
https://doaj.org/article/a6b2d0eb973c42e2be7da916ee22a4ed
Autor:
Jennifer M Curry, Tim D Eubank, Ryan D Roberts, Yijie Wang, Nabendu Pore, Amit Maity, Clay B Marsh
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3405 (2008)
BACKGROUND: M-CSF recruits mononuclear phagocytes which regulate processes such as angiogenesis and metastases in tumors. VEGF is a potent activator of angiogenesis as it promotes endothelial cell proliferation and new blood vessel formation. Previou
Externí odkaz:
https://doaj.org/article/255257ffd78c4a69a736bb7a88d76fad
Autor:
Michael D. Oberst, Maria Libera Ascierto, Phillip A. Dennis, J. Carl Barrett, Melanie M. Frigault, Rajiv Raja, Shaad E. Abdullah, Ashok Gupta, Ronald Herbst, Ricardo J. Miragaia, Theresa A. Proia, Ina Bisha, Matthew Griffin, John Meekin, Philip Martin, Stephen Blackmore, Kathy Mulgrew, Raymond Rothstein, Rebecca Halpin, Yashaswi Shrestha, Melissa de los Reyes, Maria Jure-Kunkel, Nathan Standifer, Song Wu, Nabendu Pore
Marker genes for the monocyte-macrophage-DC subpopulations identified in Supplementary Figure 5H. Only genes with adjusted p-value < 0.01 and average log fold-change > 0.3 were included. gene, gene name; p_val, p-value calculated based on Wilcoxon te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318ab2f876a4f6d65d1cc34e89e50b21
https://doi.org/10.1158/2159-8290.22540394
https://doi.org/10.1158/2159-8290.22540394
Autor:
Michael D. Oberst, Maria Libera Ascierto, Phillip A. Dennis, J. Carl Barrett, Melanie M. Frigault, Rajiv Raja, Shaad E. Abdullah, Ashok Gupta, Ronald Herbst, Ricardo J. Miragaia, Theresa A. Proia, Ina Bisha, Matthew Griffin, John Meekin, Philip Martin, Stephen Blackmore, Kathy Mulgrew, Raymond Rothstein, Rebecca Halpin, Yashaswi Shrestha, Melissa de los Reyes, Maria Jure-Kunkel, Nathan Standifer, Song Wu, Nabendu Pore
Pharmacodynamics of STAT3 ASO in CT26 STK11 KO model. (A) Percentage of CD45+ immune cells among live cells from untreated or drug-treated STK11 KO CT26 tumors as indicated. (B) Percentage of Ly6G+ granulocytic cells among live CD45+ cells. (C) Perce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c1f0437b345d54961ba0824610dcb6
https://doi.org/10.1158/2159-8290.22540439.v1
https://doi.org/10.1158/2159-8290.22540439.v1
Autor:
Michael D. Oberst, Maria Libera Ascierto, Phillip A. Dennis, J. Carl Barrett, Melanie M. Frigault, Rajiv Raja, Shaad E. Abdullah, Ashok Gupta, Ronald Herbst, Ricardo J. Miragaia, Theresa A. Proia, Ina Bisha, Matthew Griffin, John Meekin, Philip Martin, Stephen Blackmore, Kathy Mulgrew, Raymond Rothstein, Rebecca Halpin, Yashaswi Shrestha, Melissa de los Reyes, Maria Jure-Kunkel, Nathan Standifer, Song Wu, Nabendu Pore
Supplementary Appendix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ac7dc7f83ade0389ea5b8926dfead1
https://doi.org/10.1158/2159-8290.22540454.v1
https://doi.org/10.1158/2159-8290.22540454.v1
Autor:
Michael D. Oberst, Maria Libera Ascierto, Phillip A. Dennis, J. Carl Barrett, Melanie M. Frigault, Rajiv Raja, Shaad E. Abdullah, Ashok Gupta, Ronald Herbst, Ricardo J. Miragaia, Theresa A. Proia, Ina Bisha, Matthew Griffin, John Meekin, Philip Martin, Stephen Blackmore, Kathy Mulgrew, Raymond Rothstein, Rebecca Halpin, Yashaswi Shrestha, Melissa de los Reyes, Maria Jure-Kunkel, Nathan Standifer, Song Wu, Nabendu Pore
Mutations in the STK11 (LKB1) gene regulate resistance to PD-1/PD-L1 blockade. This study evaluated this association in patients with nonsquamous non–small cell lung cancer (NSCLC) enrolled in three phase I/II trials. STK11 mutations were associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99faa4f93ebec463e8a33a4c093c1abb
https://doi.org/10.1158/2159-8290.c.6549368.v1
https://doi.org/10.1158/2159-8290.c.6549368.v1