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pro vyhledávání: '"Nabel, G J"'
Autor:
Sarwar, U. N., Costner, P., Enama, M. E., Berkowitz, N., Hu, Z., Hendel, C. S., Sitar, S., Plummer, S., Mulangu, S., Bailer, R. T., Koup, R. A., Mascola, J. R., Nabel, G. J., Sullivan, N. J., Graham, B. S., Ledgerwood, J. E., Gordon, I., Holman, L., Mendoza, F., Novik, L., Saunders, J., Zephir, K., Desai, N., Young, S., Casazza, J., Larkin, B., Yamshchikov, G., Vasilenko, O., Gomez, P. L., Andrews, C., Conan-Cibotti, M., Wallace, K., Stein, J., Sheets, R., Decederfelt, H., Starling, J., Renehan, P.
Publikováno v:
Journal of Infectious Diseases
Background. Ebolavirus and Marburgvirus cause severe hemorrhagic fever with high mortality and are potential bioterrorism agents. There are no available vaccines or therapeutic agents. Previous clinical trials evaluated transmembrane-deleted and poin
Akademický článek
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Autor:
Nabel, G. J.
Haynes et al. discuss recent findings in Science and Nature Medicine about antibodies directed to the membrane-proximal region (MPR) of the HIV-1 envelope (ENV) glycoprotein and their possible therapeutic utility. Although these antibodies have the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::27fa48f1ecce506695b45d3b702d6485
https://zenodo.org/record/1230862
https://zenodo.org/record/1230862
Autor:
Nabel, G. J.
In many ways, Ebola virus infection provides a model for understanding the toxicity of viruses and their causal role in human disease. The highly aggressive course of Ebola virus infection provides a model for understanding the molecular mechanisms o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64f3ff14b1b1bea90767885d76a9a7e8
https://europepmc.org/articles/PMC2194412/
https://europepmc.org/articles/PMC2194412/
BACKGROUND: Gene transfer into vascular smooth muscle cells (vsmcs) holds promise for studying the pathogenesis of arterial disorders. However, a potential limitation of vectors with heterologous promoters is organ toxicity resulting from unrestricte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b788eed2fd21122bcc14a615e57a7916
https://europepmc.org/articles/PMC1949920/
https://europepmc.org/articles/PMC1949920/
Autor:
Simari, R. D., Yang, Z. Y., Ling, X., Stephan, D., Perkins, N. D., Nabel, G. J., Nabel, E. G.
BACKGROUND: The cytomegalovirus immediate early (CMV IE) promoter has been widely used for heterologous expression. Further enhancements of gene expression from this potent promoter may allow for the development of improved gene transfer strategies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d9c2800ba53bbfdc3046d74d19fb3d9
https://europepmc.org/articles/PMC2230344/
https://europepmc.org/articles/PMC2230344/
BACKGROUND: Balloon injury of the arterial wall induces increased vascular smooth cell proliferation, enhanced elastic recoil, and abnormalities in thrombosis, each of which contribute to regrowth of intima and the lesion of restenosis. Several gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5522ca1211d94a27e15b7faf534472a
https://europepmc.org/articles/PMC2230084/
https://europepmc.org/articles/PMC2230084/
BACKGROUND: Vascular smooth muscle cell (VSMC) proliferation following arterial injury plays a critical role in a variety of vascular proliferative disorders, including atherosclerosis and restenosis after balloon angioplasty. In this study, we teste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5951e8403df25f14ca785d9d1b102917
https://europepmc.org/articles/PMC2229941/
https://europepmc.org/articles/PMC2229941/
Inducible expression of human immunodeficiency virus (HIV) is regulated by a cellular transcription factor, nuclear factor kappa B (NF-kappa B). NF-kappa B is composed of distinct subunits; five independent genes, NFKB1(p105), NFKB2(p100), RelA(p65),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::757ff471f5a9e8147321a8d96ce5ac98