Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nabeela Majid"'
Autor:
Mohammad K. Siddiqi, Parvez Alam, Tabish Iqbal, Nabeela Majid, Sadia Malik, Saima Nusrat, Aftab Alam, Mohd R. Ajmal, Vladimir N. Uversky, Rizwan H. Khan
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Inhibition of fibrillation process and disaggregation of mature fibrils using small peptide are the promising remedial strategies to combat neurodegenerative diseases. However, designing peptide-based drugs to target β-sheet-rich amyloid has been a
Externí odkaz:
https://doaj.org/article/9e5de98b4e594f13b6cc49ac86c6f337
Autor:
Sadia Malik, Mohammad Khursheed Siddiqi, Nida Naseem, Faisal Nabi, Aiman Masroor, Nabeela Majid, Amiruddin Hashmi, Rizwan Hasan Khan
Publikováno v:
Biochimie. 211:110-121
Autor:
Nabeela Majid, Mohammad Khursheed Siddiqi, Md. Nadir Hassan, Sadia Malik, Seema Khan, Rizwan Hasan Khan
Publikováno v:
Biomaterials Advances. 151:213450
Autor:
Gopal N. Srivastava, Elaheh Hadi Zadeh, Hossein Ashrafian, Mahmood Tajbakhsh, Rizwan Hasan Khan, Nabeela Majid
Publikováno v:
International Journal of Biological Macromolecules. 183:1939-1947
Protein aggregation, such as amyloid fibril formation, is molecular hallmark of many neurodegenerative disorders including Alzheimer's, Parkinson's, and Prion disease. Indole alkaloids are well-known as the compounds having the ability to inhibit pro
Autor:
Nabeela Majid, Mohammad Khursheed Siddiqi, Rizwan Hasan Khan, Aiman Masroor, Syed Moasfar Ali, Sadia Malik
Publikováno v:
International Journal of Biological Macromolecules. 150:1258-1271
Protein misfolding and deposition of aggregated proteins inside as well as outside of the cells have been associated with several neurotoxic and neurodegenerative disorders like Alzheimer's, Parkinson's and familial amyloid polyneuropathy etc. that c
Autor:
Nabeela Majid, Mohammad Khursheed Siddiqi, Parvez Alam, Aftab Alam, Rizwan Hasan Khan, Mohd Rehan Ajmal, Sudeepa Rajan, Sadia Malik
Publikováno v:
International Journal of Biological Macromolecules. 143:102-111
For the first time, the effect of two novel designed pentapeptides on amyloid growth of human insulin using combined biophysical, microscopic, cell viability and computational approaches. Collective experimental data from ThT, ANS, and TEM demonstrat
Autor:
Nabeela Majid, Rizwan Hasan Khan, Fahad M. Almutairi, Mohammad Rehan Ajmal, Ali S. Abdelhameed, Adel I. Alalawy, Mohammad Khursheed Siddiqi
Publikováno v:
Journal of biomolecular structuredynamics. 39(5)
Interaction of levocabastine with human serum albumin (HSA) is investigated by applying fluorescence spectroscopy, circular dichroism spectroscopy and molecular docking methods. Levocabastine is an important drug in treatment of allergy and currently
Publikováno v:
Sub-cellular biochemistry. 93
Amyloid diseases are of major concern all over the world due to a number of factors including: (i) aging population, (ii) increasing life span and (iii) lack of effective pharmacotherapy options. The past decade has seen intense research in discoveri
Autor:
Ali S. Abdelhameed, Masihuz Zaman, Mohd Rehan Ajmal, Mohammad Khursheed Siddiqui, Yasser E. Shahein, Rizwan Hasan Khan, Mohd Ishtikhar, Mohsin Vahid Khan, Nabeela Majid, Tajalli Ilm Chandel
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 36:1261-1273
The aggregation phenomenon (amyloid and amorphous) is associated with several pathological complications in human, such as Alzheimer's, Parkinson's, Huntington, Cataract diseases, and Diabetes mellitus type 2. In the present study we are offering evi
Autor:
Sadia Malik, Rizwan Hasan Khan, Nabeela Majid, Asra Nasir Khan, Mohammad Khursheed Siddiqi, Vladimir N. Uversky, Shabnam Shabnam, Aftab Alam
Publikováno v:
ACS chemical neuroscience. 10(11)
Protein misfolding and its deviant self-assembly to converge into amyloid fibrils is associated with the perturbation of cellular functions and thus with debilitating neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, etc.