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Hydroxyurea Therapy for Neurological and Cognitive Protection in Pediatric Sickle Cell Anemia in Uganda (BRAIN SAFE II): Protocol for a single-arm open label trial.

Autor: Mboizi V; Global Health Uganda, Kampala, Uganda., Nabaggala C; Global Health Uganda, Kampala, Uganda., Munube D; Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda., Ssenkusu JM; Department of Epidemiology and Biostatistics, Makerere University School of Public Health, Kampala, Uganda., Kasirye P; Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda., Kamya S; Ernest Cook Ultrasound Research and Education Institute (ECUREI), Mengo Hospital, Kampala, Uganda., Kawooya MG; Ernest Cook Ultrasound Research and Education Institute (ECUREI), Mengo Hospital, Kampala, Uganda., Boehme A; Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA., Minja F; Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia, USA., Mupere E; Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda., Opoka R; Global Health Uganda, Kampala, Uganda.; Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda., Rosano C; Department of Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA., Green NS; Department of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA., Idro R; Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Jan 13. Date of Electronic Publication: 2024 Jan 13.