Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Naama Kessler"'
Autor:
Naama Kessler, Lewis E. Kay, Suresh Kumar, Jacob Solanki, Leah S. Cohen, Sabine R. Akabayov, Fred Naider, Jacob Anglister
Publikováno v:
Journal of Biomolecular NMR. 74:681-693
Many proteins interact with their ligand proteins by recognition of short linear motifs that are often intrinsically disordered. These interactions are usually weak and are characterized by fast exchange. NMR spectroscopy is a powerful tool to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60629cda9ed6a2b8c0772cb0224fe786
https://doi.org/10.1007/s10858-020-00340-y
https://doi.org/10.1007/s10858-020-00340-y
Autor:
Lewis E. Kay, Jacob Anglister, Brandon Fridman, Naama Kessler, Fred Naider, Leah S. Cohen, Adi Moseri, Damir Sakhapov, David Bolton, Sabine R. Akabayov
Publikováno v:
The FEBS journalReferences. 288(5)
The N-terminal segment of the chemokine receptor Human CC chemokine receptor 5 (CCR5), Nt-CCR5, contains four tyrosine residues, Y3, Y10, Y14, and Y15. Sulfation of at least two of these tyrosine residues was found to be essential for high-affinity b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ad58b9be89d99a46f908ed3ae265e8
https://pubmed.ncbi.nlm.nih.gov/32814359
https://pubmed.ncbi.nlm.nih.gov/32814359
Publikováno v:
The FEBS Journal. 285:4296-4310
Infection by HIV-1 requires protein-protein interactions involving gp120, CD4 and CCR5. We have previously demonstrated that the transferred nuclear Overhauser effect (TRNOE), in combination with asymmetric deuteration of a protein and a peptide liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e6b8cb016949de4a10b8b0b08c1163
https://doi.org/10.1111/febs.14673
https://doi.org/10.1111/febs.14673
Autor:
Zippora Shakked, Itai Beno, Zhiqun Xi, Naama Kessler, Tali E. Haran, Varda Rotter, Dmitrij Golovenko, Pratik Vyas, Yan Stein
Publikováno v:
Proceedings of the National Academy of Sciences. 114:10624-10629
The tumor suppressor protein p53 acts as a transcription factor, binding sequence-specifically to defined DNA sites, thereby activating the expression of genes leading to diverse cellular outcomes. Canonical p53 response elements (REs) are made of tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6e8cc78cffee4a1a3e873fdf75db61
https://doi.org/10.1073/pnas.1618005114
https://doi.org/10.1073/pnas.1618005114
Autor:
Gautam Srivastava, Sabine R. Akabayov, Fred Naider, Naama Kessler, Jacob Anglister, Adi Moseri, Boris Arshava
Publikováno v:
The FEBS Journal. 283:4084-4096
Weak protein-protein and protein-ligand interactions play important roles in biological recognition. In many cases, simplification of structural studies of large protein complexes is achieved by investigation of the interaction between the protein an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe999a646e27d59f38d86ad3ac3568e
https://doi.org/10.1111/febs.13916
https://doi.org/10.1111/febs.13916
Publikováno v:
Biophysical Journal. 109(6):1157-1162
The Engrailed Homeodomain (EnHD) transcription factor of Drosophila melanogaster was fused to the enhanced green fluorescent protein (eGFP) either at its C- or N-terminus via three- or ten-residue flexible linkers. Here, we show that EnHD undergoes d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0275794be4bb1834ee844455e21c59b3
Autor:
Meital Abayev, Oren Tchaicheeyan, Jacob Anglister, Naama Kessler, Adi Moseri, Fred Naider, Tali Scherf, Boris Arshava
Publikováno v:
FEBS Journal. 282:1906-1921
C-C chemokine receptor 5 (CCR5) serves as a co-receptor for HIV-1. The CCR5 N-terminal segment, the second extracellular loop (ECL2) and the transmembrane helices have been implicated in binding the envelope glycoprotein gp120. Peptides corresponding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ac681435d098a29c6bcca5df00372d
https://doi.org/10.1111/febs.13243
https://doi.org/10.1111/febs.13243
Autor:
Fa-Xiang Ding, Naama Kessler, Hasmik Sargsyan, Tali Scherf, Eran Noah, Boris Arshava, Fred Naider, Tatsuya Inui, Inbal Ayzenshtat, Jacob Anglister, Einat Schnur, Yael Sagi, Rina Levy
Publikováno v:
Journal of Molecular Biology. 410:778-797
Interaction of CC chemokine receptor 5 (CCR5) with the human immunodeficiency virus type 1 (HIV-1) gp120/CD4 complex involves its amino-terminal domain (Nt-CCR5) and requires sulfation of two to four tyrosine residues in Nt-CCR5. The conformation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292d31f8574275855eb273e4fc4635e4
https://doi.org/10.1016/j.jmb.2011.04.023
https://doi.org/10.1016/j.jmb.2011.04.023
Publikováno v:
Protein Science. 20:160-167
The crystal structure of Phenylalanyl-tRNA synthetase from E. coli (EcPheRS), a class II aminoacyl-tRNA synthetase, complexed with phenylalanine and AMP was determined at 3.05 Aresolution. EcPheRS is a (ab)2 heterotetramer: the ab heterodimer of EcPh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cd308b4fcd614fa7e8dc771bffb066f
https://doi.org/10.1002/pro.549
https://doi.org/10.1002/pro.549
Publikováno v:
Structure. 18(3):343-353
The existence of three types of phenylalanyl-tRNA synthetase (PheRS), bacterial (alphabeta)(2), eukaryotic/archaeal cytosolic (alphabeta)(2), and mitochondrial alpha, is a prominent example of structural diversity within the aaRS family. PheRSs have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84895820c5e0c8afee8415fc10f6468d