Pharmacokinetics and pharmacodynamics of Abelacimab (MAA868), a novel dual inhibitor of Factor XI and Factor XIa

Autor: Dan Bloomfield, Naab M. Al‐Saady, Debra Freedholm, Sara Coulter, Norman E. Lepor, Xiaohui Wang, Nancy Widener, Mark Lovern, Constance Cullen, Byungdoo Alexander Yi, Emilie Simard

Publikováno v: Journal of Thrombosis and Haemostasis. 20:307-315

Background Factor XI (FXI) inhibition offers the promise of hemostasis-sparing anticoagulation for the prevention and treatment of thromboembolic events. Abelacimab (MAA868) is a novel fully human monoclonal antibody that targets the catalytic domain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2022a6f5c2560d66f2ddc2a3e2cc7c
https://doi.org/10.1111/jth.15577

Software risk management in practice: Shed light on your software product

Autor: Knodel, J., Naab, M., Bouwers, E., Visser, J., Guéhéneuc, Y.-G.

Publikováno v: SANER
Guéhéneuc, Y.-G. (ed.), SANER 2015 : IEEE 22nd International Conference on Software Analysis, Evolution, and Reengineering. Proceedings. March 2-6, 2015, Montreal, Canada, 592-594. Piscataway : IEEE
STARTPAGE=592;ENDPAGE=594;TITLE=Guéhéneuc, Y.-G. (ed.), SANER 2015 : IEEE 22nd International Conference on Software Analysis, Evolution, and Reengineering. Proceedings. March 2-6, 2015, Montreal, Canada
Guéhéneuc, Y.-G. (ed.), SANER 2015 : IEEE 22nd International Conference on Software Analysis, Evolution, and Reengineering. Proceedings. March 2-6, 2015, Montreal, Canada, pp. 592-594

You can't control what you can't measure. And you can't decide if you are wandering around in the dark. Risk management in practice requires shedding light on the internals of the software product in order to make informed decisions. Thus, in practic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292d4440ac9f737a776b231dca11123a
https://hdl.handle.net/2066/141424

Case studies of static software architecture evaluations

Autor: Knodel, J., Lindvall, M., Muthig, D., Naab, M.

Architecture evaluations play an important role in the development and evolution of software systems since they determine how adequate the architecture is for its intended usage. This paper summarizes our practical experience with using static archit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::3a4de38d9420cb3b1e509ee3f64528ac
https://publica.fraunhofer.de/handle/publica/210575

Evaluation of graphical elements and their adequacy for the visualization of software architectures

Autor: Naab, M., Forster, T., Knodel, J., Muthig, D.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::386a3e0433f04b7df26832a6e1061846

A Method for Collaborative Development of Systems of Systems in the Office Domain.

Autor: Carbon, R., Johann, G., Muthig, D., Naab, M.

Publikováno v: 2008 12th International IEEE Enterprise Distributed Object Computing Conference; 2008, p339-345, 7p