Extracellular Vesicles and Their Convergence with Viral Pathways

Autor: Leonora Balaj, Balveen Kaur, Xandra O. Breakefield, Thomas Wurdinger, D. Michiel Pegtel, NaTosha N. Gatson

Publikováno v: Advances in Virology
Würdinger, T, Gatson, N N, Balaj, L, Kaur, B, Breakefield, X O & Pegtel, D M 2012, ' Extracellular vesicles and their convergence with viral pathways ', Advances in Virology, vol. 2012, 767694 . https://doi.org/10.1155/2012/767694
Advances in Virology, 2012:767694. Hindawi Publishing Corporation
Advances in Virology, Vol 2012 (2012)

Extracellular vesicles (microvesicles), such as exosomes and shed microvesicles, contain a variety of molecules including proteins, lipids, and nucleic acids. Microvesicles appear mostly to originate from multivesicular bodies or to bud from the plas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb53b0921836be943d7c23b844b3da8
https://doi.org/10.1155/2012/767694

Pregnancy suppresses experimental autoimmune encephalomyelitis through immunoregulatory cytokine production

Autor: Caroline C. Whitacre, Ingrid E. Gienapp, Nicole D. Powell, Tracey L. Papenfuss, Melanie A. McClain, Aaron P. Kithcart, Fei Song, NaTosha N. Gatson, Todd Shawler

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 179(12)

Women with multiple sclerosis (MS) often experience a decrease in relapse rate during pregnancy, most notably during the third trimester, with a flare of disease activity 3–6 mo postpartum. Studies in experimental autoimmune encephalomyelitis (EAE)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3877f4c2e89b6fe1bad1ab9fd708b41f
https://pubmed.ncbi.nlm.nih.gov/18056357

A distinct role for PI3Kgamma in suppressing the development and progression of experimental autoimmune encephalomyelitis (EAE) (129.30)

Autor: NaTosha N Gatson, H Ji, I E Gienapp, F Song, T L Papenfuss, M Camps, T Ruckle, J L Zimmerer, T M Shawler, B Lu, C Gerard, A P Kithcart, N Powell, A J Fischer, A Satoskar, C Rommel, C C Whitacre

Publikováno v: The Journal of Immunology. 178:S223-S223

Phosphoinositide 3-kinases (PI3K) are intracellular signaling proteins involved in cellular responses such as chemotaxis, proliferation and apoptosis. Selective inhibitors of the PI3Kγ-isoform have recently become available. This study explores the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c377e4d102930917446825b20601517
https://doi.org/10.4049/jimmunol.178.supp.129.30