Zobrazeno 1 - 10
of 60
pro vyhledávání: '"NaCl, sodium chloride"'
Autor:
Cong Luo, Bingjun Sun, Zhiqiang Kong, Xuanbo Zhang, Yuequan Wang, Jin Sun, Zhonggui He, Qin Chen, Shenwu Zhang, Han Yu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3636-3647 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Pure drug-assembled nanomedicines (PDANs) are currently under intensive investigation as promising nanoplatforms for cancer therapy. However, poor colloidal stability and less tumor-homing ability remain critical unresolved problems that impede their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9acead0b5e7eab216fb1cd974de302
https://doi.org/10.1016/j.apsb.2021.04.005
https://doi.org/10.1016/j.apsb.2021.04.005
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1117-1128 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1117-1128 (2021)
Hypertension is the largest risk factor for cardiovascular disease, the leading cause of mortality worldwide. As blood pressure regulation is influenced by multiple physiological systems, hypertension cannot be attributed to a single identifiable eti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cf89adceb9ad5521b4a16ae65dbf60
https://doi.org/10.1016/j.apsb.2020.09.009
https://doi.org/10.1016/j.apsb.2020.09.009
Publikováno v:
Journal of Traditional and Complementary Medicine
Journal of Traditional and Complementary Medicine, Vol 11, Iss 2, Pp 82-89 (2021)
Journal of Traditional and Complementary Medicine, Vol 11, Iss 2, Pp 82-89 (2021)
Background and aim Decoctions and infusions from the aerial parts of Portulaca oleracea Linn., especially the leaves and stems, are used by traditional medicine practitioners in Nigeria to enhance fertility in humans. The scarcity of literature on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d3805bfecc6fea2882291cb69fd022
http://europepmc.org/articles/PMC7936097
http://europepmc.org/articles/PMC7936097
Akademický článek
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Autor:
Pimchai Chaiyen, Jirawat Tantipisit, Asweena Binlaeh, Litavadee Chuaboon, Juthamas Jaroensuk, Somchart Maenpuen, Penchit Chitnumsub, Ruchanok Tinikul, Aritsara Jaruwat, Jittima Phonbuppha, Pratchaya Watthaisong, Narin Lawan
Publikováno v:
The Journal of Biological Chemistry
Aldolases catalyze the reversible reactions of aldol condensation and cleavage and have strong potential for the synthesis of chiral compounds, widely used in pharmaceuticals. Here, we investigated a new Class II metal aldolase from the p-hydroxyphen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ec40387511a3835e3f518a5fda0050
http://europepmc.org/articles/PMC8560999
http://europepmc.org/articles/PMC8560999
Autor:
Monika Dzieciatkowska, Lauren R. Schmitt, Toin H. van Kuppevelt, Willeke F. Daamen, Mark Maslanka, Ryan C. Hill, Maxwell C. McCabe, Kirk C. Hansen, Danique J. Hof
Publikováno v:
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics, 20
Molecular & Cellular Proteomics, 20
The extracellular matrix is a key component of tissues, yet it is underrepresented in proteomic datasets. Identification and evaluation of proteins in the extracellular matrix (ECM) has proved challenging due to the insolubility of many ECM proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2083f5875a9c4968507a0ff8208d5d
http://europepmc.org/articles/PMC8188056
http://europepmc.org/articles/PMC8188056
Autor:
Yuan, Xiong, Guang-Hao, Zhu, Ya-Ni, Zhang, Qing, Hu, Hao-Nan, Wang, Hao-Nan, Yu, Xiao-Ya, Qin, Xiao-Qing, Guan, Yan-Wei, Xiang, Hui, Tang, Guang-Bo, Ge
Publikováno v:
International Journal of Biological Macromolecules
Coronavirus 3C-like protease (3CLpro) is a crucial target for treating coronavirus diseases including COVID-19. Our preliminary screening showed that Ampelopsis grossedentata extract (AGE) displayed potent SARS-CoV-2-3CLpro inhibitory activity, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aade985145c08b4d833f2ce6ec1be30b
https://pubmed.ncbi.nlm.nih.gov/34333006
https://pubmed.ncbi.nlm.nih.gov/34333006
Autor:
Bruno Hagenbuch, Shipra Malhotra, Aron W. Fenton, Liskin Swint-Kruse, Melissa Ruggiero, John Karanicolas
Publikováno v:
The Journal of Biological Chemistry
Conventionally, most amino acid substitutions at "important" protein positions are expected to abolish function. However, in several soluble-globular proteins, we identified a class of nonconserved positions for which various substitutions produced p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1342959ef3eb7d12e979ca49a3687606
http://europepmc.org/articles/PMC7948949
http://europepmc.org/articles/PMC7948949
Autor:
Anna, Posod, Ira, Winkler, Karina, Wegleiter, Eva, Huber, Martina, Urbanek, Ursula, Kiechl-Kohlendorfer, Elke, Griesmaier
Publikováno v:
IBRO Reports
Highlights • Levomepromazine (LMP) does not induce cell death in the healthy developing brain. • Excitotoxic lesion size and apoptosis are unaffected by LMP. • Body weight gain is reduced in mouse pups receiving higher-dose LMP treatment. • F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14b91d243b86dcde25f5d5ac3dbd304a
https://pubmed.ncbi.nlm.nih.gov/33024879
https://pubmed.ncbi.nlm.nih.gov/33024879
Publikováno v:
The Journal of Biological Chemistry
Heterodimeric KIF3AC is a mammalian kinesin-2 that is highly expressed in the central nervous system and associated with vesicles in neurons. KIF3AC is an intriguing member of the kinesin-2 family because the intrinsic kinetics of KIF3A and KIF3C whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a791803a832d69e7a77c217fa0e07c7b
https://pubmed.ncbi.nlm.nih.gov/33144324
https://pubmed.ncbi.nlm.nih.gov/33144324