Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Na Xian"'
Autor:
Li Hu, Ling Chen, Zexiu Xiao, Xu Zheng, Yuangui Chen, Na Xian, Christina Cho, Liqun Luo, Gangxiong Huang, Lieping Chen
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
Programmed death-1 homolog (PD-1H) is a coinhibitory molecule that negatively regulates T cell–mediated immune responses. In this study, we determined whether ablation of T cell–associated PD-1H could enhance adoptive T cell therapy in experiment
Externí odkaz:
https://doaj.org/article/2cd731fd40de49e68a8329ef38db7ce0
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Esophageal squamous cell carcinoma (ESCC) is the most common type of esophageal carcinoma (EC) in China. Although the PD-1 inhibitor pembrolizumab has been approved to treat patients with EC, its therapeutic efficacy is limited. Thus, additional immu
Externí odkaz:
https://doaj.org/article/2b4dbadc6f364d31a705c2a458fecff4
Autor:
Baozhu Huang, Liqun Luo, Jun Wang, Bailin He, Rui Feng, Na Xian, Qiong Zhang, Lieping Chen, Gangxiong Huang
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
The application of chimeric antigen receptor (CAR)-T cell therapy in patients with advanced solid tumors remains a significant challenge. Simultaneously targeting antigen and the solid tumor microenvironment are two major factors that greatly impact
Externí odkaz:
https://doaj.org/article/d823745600364301b6b7d89653804a05
Publikováno v:
Czech Journal of Food Sciences, Vol 36, Iss 4, Pp 349-356 (2018)
Effects of partial replacement of wheat flour with corn flour (2.93-17.07%) blended with xanthan gum (0.1172-0.6828%) on physical properties, textural and sensory characteristics of sponge cakes were evaluated by response surface methodology (RSM). T
Externí odkaz:
https://doaj.org/article/9994d83ad13441d993c1218f29cdf256
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 5, Pp 752-757 (2016)
In this study, we investigated the role of the TYRO3/Akt signaling pathway in hypoxic injury to hippocampal neurons. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay showed that hypoxia inhibited the proliferation and viability of h
Externí odkaz:
https://doaj.org/article/ad3967a7a0634162a10c24f06cea8c8c
Autor:
Jing Ren, Chao Wu, Mengxia Zeng, Mingqin Qu, Ge Gao, Ning Chen, Jingjing Yue, Yuwen Jiang, Tongfei Zhao, Na Xiang, Fangang Meng, Ling-ling Lu
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract To investigate physiological function of α-synuclein is important for understanding its pathophysiological mechanism in synucleinopathies including Parkinson’s disease. Employing knockout mice, we found that Snac/α-synuclein deletion ind
Externí odkaz:
https://doaj.org/article/280939f9b7474a71acff6b680305c693
Autor:
Li-Na Xian, Yuan-Zheng Yang
Publikováno v:
Journal of Hainan Medical University, Vol 27, Iss 13, Pp 29-33 (2021)
Objective: To explore the clinical value of dynamic ultrasound monitoring of optic nerve sheath diameter (ONSD) in the treatment of patients with moderate and severe head injury (CI). Methods: A total of 160 patients with moderate and severe CI admit
Publikováno v:
In Journal of Iron and Steel Research International 2007 14(6):14-21
Autor:
Xiongbin Lu, Lakshmi Reddy Bollu, Na Xian, Fei Su, James M. Briggs, Yunlu Xu, Zhang Weihua, Rintu Thomas, Bing Wu, Michael A. Rea, Rajasekhara Reddy Katreddy, Shivangi Srivastava, Qingyuan Zhang, Gangxiong Huang, Yubing Dai
Publikováno v:
Oncogenesis, Vol 7, Iss 1, Pp 1-13 (2018)
Oncogenesis
Oncogenesis
The oncogenic epidermal growth factor receptor (EGFR) is commonly overexpressed in solid cancers. The tyrosine kinase activity of EGFR has been a major therapeutic target for cancer; however, the efficacy of EGFR tyrosine kinase inhibitors to treat c
Autor:
Li-Na Xian, Ying Li, Jun-Yi Yao, Ying-Qing Li, Shao-Wen Cheng, Xiu-Ru Li, Chuan-Zhu Lyu, Wei-Cheng Wang, Yong-Yan Li, Zhi-Xing Lin, Xue Ao
Publikováno v:
Asian Pacific Journal of Tropical Medicine, Vol 11, Iss 3, Pp 251-254 (2018)
Objective: To detect the clinical relevance of mannose-binding lectin 2 (MBL2) gene polymorphism and sepsis in Chinese lived in Hainan island. Methods: Blood samples from 57 patients with sepsis and 69 patients without sepsis were collected in the IC