Zobrazeno 1 - 10
of 317
pro vyhledávání: '"NUPR1"'
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 8813-8830 (2024)
Bowen Xu,1,2,* Hongye Li,1,2,* Hongping Chen,3 Da Teng,1,2 Lei Gong,2 Lin Zhong,2 Jun Yang2 1Qingdao Medical College of Qingdao University, Qingdao, Shandong, 266000, People’s Republic of China; 2Department of Cardiology, Yantai Yuhuangding
Externí odkaz:
https://doaj.org/article/2bf2e825a7044dd3b876417a4624cc7f
Autor:
Qiong Wu, Qiuhong Chen, Sisi Liang, Jinping Nie, Yingjie Wang, Chenlu Fan, Zhen Liu, Xuekang Zhang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-20 (2024)
Abstract Intestinal ischemia/reperfusion injury (I/R) is a common yet challenging-to-treat condition, presenting a significant clinical challenge. This study aims to investigate the protective mechanisms of Dexmedetomidine (Dex) against I/R injury, w
Externí odkaz:
https://doaj.org/article/d3f4a2e0da0440e8a10eab42537d4c78
Autor:
Yongliang Lu, Weihao Chen, Yundong Xuan, Xiubin Li, Shengpan Wu, Hanfeng Wang, Tao Guo, Chenfeng Wang, Shuo Tian, Huaikang Li, Dong Lai, Wenlei Zhao, Xing Huang, Xupeng Zhao, Baojun Wang, Xu Zhang, Hongzhao Li, Yan Huang, Xin Ma
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Cancer cells encounter unavoidable stress during tumor growth. The stress-induced transcription factor, activating transcription factor 4 (ATF4), has been reported to upregulate various adaptive genes involved in salvage pathways to alleviat
Externí odkaz:
https://doaj.org/article/b37adf6177d34bb09b6a9d976e38a2c2
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e38918- (2024)
Objective: This study aimed to investigate the role of Nuclear Protein 1 (NUPR1) in pulmonary embolism (PE) and its impact on the phenotypic transformation of pulmonary artery smooth muscle cells (PASMCs). Methods: A PE model was established via auto
Externí odkaz:
https://doaj.org/article/d31b97ebd0264410be341b8b23534146
Autor:
Xiao-Yu Zhang, Shan-Shan Li, Yu-Rong Gu, Le-Xin Xiao, Xin-Yi Ma, Xin-Ru Chen, Jia-Liang Wang, Chun-Hong Liao, Bing-Liang Lin, Yue-Hua Huang, Yi-Fan Lian
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background The role of circRNAs in hepatocellular carcinoma (HCC) progression remains unclear. CircPIAS1 (circBase ID: hsa_circ_0007088) was identified as overexpressed in HCC cases through bioinformatics analysis. This study aimed to invest
Externí odkaz:
https://doaj.org/article/ab3542d189c14f4382118dd603e564b4
Akademický článek
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Autor:
Patricia Santofimia-Castaño, Nicolas Fraunhoffer, Xi Liu, Ivan Fernandez Bessone, Marina Pasca di Magliano, Stephane Audebert, Luc Camoin, Matias Estaras, Manon Brenière, Mauro Modesti, Gwen Lomberk, Raul Urrutia, Philippe Soubeyran, Jose Luis Neira, Juan Iovanna
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 475-505 (2024)
Abstract We find that NUPR1, a stress-associated intrinsically disordered protein, induced droplet formation via liquid–liquid phase separation (LLPS). NUPR1-driven LLPS was crucial for the creation of NUPR1-dependent stress granules (SGs) in pancr
Externí odkaz:
https://doaj.org/article/d6378f109e874a1da4c8222d7dc3b37c
Publikováno v:
Open Medicine, Vol 18, Iss 1, Pp 1367-80 (2023)
The stress response molecule nuclear protein‑1 (NUPR1) is essential for the growth of multiple types of human malignant tumor cells. However, the significance of NUPR1 in lung cancer is still not entirely elucidated. Therefore, this study is aimed
Externí odkaz:
https://doaj.org/article/fe2e05a2021c418fa447beb12ac8cc79
Autor:
Lifeng Zhang, Shenglin Gao, Xiaokai Shi, Yin Chen, Shuzhang Wei, Yuanyuan Mi, Li Zuo, Chunjian Qi
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 7149-7163 (2023)
Abstract Background NUPR1, or p8, is a small chromatin protein that plays a central role in the resistance to treatment and progression of cancer. Nevertheless, the molecular mechanism of NUPR1 in bladder cancer (BLCA) remains unclear. Methods We use
Externí odkaz:
https://doaj.org/article/3fa7215846ae480e9f0b2dcffb6dc3dc
Autor:
Yizhi Zhan, Zhanqiao Zhang, Yuechen Liu, Yuan Fang, Yuwen Xie, Yilin Zheng, Guoxin Li, Li Liang, Yi Ding
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Radiotherapy (RT) is one of the major therapeutic approaches to hepatocellular carcinoma (HCC). Ionizing radiation (IR) inducing the generation of reactive oxygen species (ROS) leads to a promising antitumor effect. However, the d
Externí odkaz:
https://doaj.org/article/29125362ba9f4b8bb2a1eca32d39e083